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    v1.0.30
    OpenPayerBilling CodesDestruction Procedures on the PenisCPT cpt-54057-laser-destruction-penile-skin-lesion
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    CPT 54057: Laser Destruction of Penile Skin Lesion

    Medicare pays $149 on average nationally for this procedure.

    CPT code 54057 describes destruction of a skin lesion of the penis (for example, condyloma, papilloma, molluscum contagiosum, or herpetic vesicle) using application of a laser beam; the service is a dermatologic/surgical lesion destruction procedure and the typical site of service is an outpatient clinic, dermatology office, or ambulatory surgery center where laser ablation is performed to eradicate the lesion and relieve symptoms.

    For related coverage guidance, see recent payer policy updates: Mohs Micrographic Surgery, Mohs Micrographic Surgery, Mohs Micrographic Surgery.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 34-year-old male presents to a dermatology clinic with multiple painless verrucous papules on the glans and shaft of the penis, clinically consistent with condyloma acuminata. The provider performs a targeted procedure using a laser to ablate visible lesions after topical or local anesthetic application to improve comfort. The clinical workflow includes history and focused genital exam, informed consent documenting lesion location, size, and number, application of local anesthesia or topical analgesic as indicated, laser ablation of each lesion using CPT 54057, hemostasis as needed, and post-procedure wound care instructions. Follow-up arrangements for wound assessment and evaluation for additional lesions or topical antiviral/imiquimod therapy are documented in the medical record. Billing is submitted with the primary procedure code 54057 and appropriate modifiers to reflect professional component, bilateral or multiple site considerations, and any unusual circumstances affecting the service.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    57061Biopsy of vulva; single or multiplePre-procedure biopsy when lesion appearance is atypical and histologic diagnosis is needed.
    11100Biopsy of skin, subcutaneous tissue and/or mucous membrane (single lesion)Diagnostic biopsy of a penile lesion prior to definitive ablation when malignancy is a concern.
    54150Partial excision of penis, simple; lesion excision or removalSurgical excision alternative when lesion size or depth requires operative removal rather than laser ablation.
    99070Supplies and materials (e.g., bandages, dressings)Supplies used during and after the procedure that may be separately billable per payer rules.
    99024Postoperative follow-up visit global period unrelated servicePostoperative visits related to the procedure if billed separately under specific circumstances.

    Related Modifiers

    8 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    2084P0800X
    207P00000X
    207L00000X
    261QR0400X
    224900000X
    261QM3000X
    363LC1500X
    364SS0200X

    Related ICD-10-CM Codes

    24 rows

    ICD-10-CM CodeDescription
    A60.01Herpesviral infection of penis
    A60.02Herpesviral infection of other male genital organs
    A60.03Herpesviral cervicitis
    A60.9Anogenital herpesviral infection, unspecified
    A63.0Anogenital (venereal) warts
    B00.2Herpesviral gingivostomatitis and pharyngotonsillitis
    B00.9Herpesviral infection, unspecified
    B07.9Viral wart, unspecified
    B08.1Molluscum contagiosum
    L08.9Local infection of the skin and subcutaneous tissue, unspecified

    Showing 1–10 of 24

    Related Payer Policy Updates

    Specialty: Dermatology1 / 3

    10 rows

    PolicyPayerEffective Date
    Mohs Micrographic Surgerypremerabluecrossofwashington2027-02-05
    Mohs Micrographic Surgerypremerabluecrossofwashington2027-02-05
    Mohs Micrographic Surgerypremerabluecrossofwashington2027-02-05
    FilsuvezCigna2026-11-01
    Destruction of Pre-Malignant Skin LesionsAnthem2026-10-01
    Onychomycosis diagnostic testing and coverageOscar Health2026-10-01
    Treatment of Capillary Malformations (Port Wine Stains)universityofutahhealthplans2026-09-28
    AnzupgoCigna2026-09-15
    Hyperhidrosispriority_health_medicare2026-09-01
    Zevaskyn Coverage for Recessive Dystrophic Epidermolysis BullosaCigna2026-09-01

    Related Codes

    CPT-54050-CHEMICAL-DESTRUCTION-PENILE-SKIN-LESION

    CPT 54050: Chemical Destruction of Penile Skin Lesion

    CPT-54055-PENILE-LESION-DESTRUCTION-ELECTROSURGERY

    CPT 54055: Destruction of Skin Lesion of Penis

    CPT-54056-PENILE-LESION-CRYOTHERAPY-DESTRUCTION-LIQUID-NITROGEN

    CPT 54056: Destruction of Penile Skin Lesion by Cryotherapy

    CPT-54060-PENILE-SKIN-LESION-EXCISION-DESTRUCTION

    CPT 54060: Excision/Destruction of Skin Lesion of Penis

    CPT-54065-PENILE-LESION-DESTRUCTION

    CPT 54065: Destruction of Extensive Penile Skin Lesions

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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