CPT code 52400 represents cystourethroscopy, an endoscopic diagnostic procedure that inspects the bladder, urethra, prostatic urethra, and ureteric openings via a cystoscope passed through the urethra. As a brief, frequently performed urologic procedure, it is important across outpatient, ambulatory surgery center, and hospital outpatient settings for evaluation of hematuria, recurrent urinary tract infections, bladder cancer surveillance, and lower urinary tract symptoms. Nationally, CPT code 52400 matters because it underpins utilization, coding consistency, and payment across a wide range of outpatient urology services.

Key payers covered in this analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise clinical context for the procedure, typical sites of service, and an overview of payer coverage scope. The publication also outlines common modifiers and service-line considerations, summarizes typical procedure duration and clinical indications, and highlights where data is not available in the input. This material is intended to inform coding, billing reconciliation, and administrative planning for organizations that manage outpatient urology services.