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    v1.0.28
    OpenPayerBilling CodesUreter and Pelvis Transurethral Surgical ProceduresCPT cpt-52346-cystourethroscopy-and-intrarenal-stricture-treatment
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    CPT 52346: Cystourethroscopy with Ureteroscope and Intrarenal Stricture Treatment

    Medicare pays $397 on average nationally for this procedure.

    CPT code 52346 describes a cystourethroscopy with ureteroscope insertion into the ureters and treatment of an intrarenal stricture, a diagnostic and therapeutic endoscopic procedure performed via the urethra and bladder to inspect the urethra, prostatic urethra, bladder interior, ureteric orifices, and intrarenal collecting system; service type: endoscopic diagnostic and therapeutic procedure; typical site of service: operating room or procedure suite with cystoscopy/ureteroscopy capability.

    For related coverage guidance, see recent payer policy updates: Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use Disorders, Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use Disorders, Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use Disorders.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 58-year-old male presents with recurrent flank pain, intermittent gross hematuria, and imaging showing hydronephrosis with a suspected intrarenal collecting system stricture. The urologist schedules a combined cystourethroscopy with ureteroscopy and directed intrarenal stricture treatment. In the preoperative workflow the patient undergoes history and physical, informed consent, and preoperative anesthesia evaluation. In the operating room under general or regional anesthesia, the provider performs diagnostic cystourethroscopy using a rigid or flexible cystoscope to inspect the urethra, prostatic urethra, bladder mucosa, and ureteral orifices. A ureteral access sheath and ureteroscope are passed retrograde through the ureter into the renal pelvis and calyces to visualize the intrarenal stricture. Treatment options performed during the same session may include balloon dilation, cold knife incision, endoscopic incision with laser (e.g., holmium), or placement of a ureteral stent. Recovery includes short PACU observation, discharge with analgesia and stent care instructions when applicable, and follow-up imaging or cystoscopy to confirm resolution of the stricture and stent removal if placed.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    52353Cystourethroscopy, with ureteroscopy and/or pyeloscopy, with lithotripsy (ureteral/renal pelvis), when performedPerformed when intrarenal stone fragmentation is required during the same ureteroscopic session
    52320Cystourethroscopy, with ureteroscopy, with or without collection of specimen(s) by brushing or washingMay be used for diagnostic ureteroscopy without intrarenal stricture treatment
    52332Cystourethroscopy, with insertion of indwelling ureteral stent (eg, Gibbons or double-J), with or without dilationOften performed when a stent is placed after dilation or incision of an intrarenal stricture
    50590Lithotripsy, extracorporeal shock wave (ESWL)Alternative or adjunct treatment when stones are present; not performed endoscopically but may be part of overall care plan
    43235Endoscopic ultrasound or other unrelated GI endoscopy codesData not available in the input.

    Related Modifiers

    11 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    58Modifier 58 (Staged or related procedure/service by the same physician during the postoperative period) indicates that a subsequent procedure performed by the same provider during the…- Use modifier 58 when the same physician/QHP performs a procedure during the postoperative/global period of an earlier procedure and the subsequent procedure is either planned or anticipated…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    73Modifier 73 indicates a facility-level outpatient hospital or ASC procedure that was discontinued after the patient was prepared and taken to the procedure/operating room but before any anesthesia…- When to use: Apply CPT modifier 73 on the FACILITY (outpatient hospital or ASC) claim when the patient has been fully prepared and physically taken into the procedure/operating room but the…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…
    81Modifier -81 indicates a physician served as a minimal assistant surgeon for part—not all—of an operative procedure. Use when a physician’s assisting role is limited and does not represent full…- Use CPT modifier -81 when a physician acts as a minimum assistant surgeon who assists during only part (a limited portion) of an operative procedure; append -81 to the primary surgical CPT code to…

    Showing 1–10 of 11

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    207L00000XAnesthesiology PhysicianAn anesthesiologist is trained to provide pain relief and maintenance, or restoration, of a stable condition during and immediately following an opera…
    208D00000XGeneral Practice PhysicianA physician who specializes in the general practice of diagnosing, treating, and managing patients with a variety of illnesses and conditions.
    208000000XPediatrics PhysicianA pediatrician is concerned with the physical, emotional and social health of children from birth to young adulthood. Care encompasses a broad spectru…
    207K00000XAllergy & Immunology PhysicianAn allergist-immunologist is trained in evaluation, physical and laboratory diagnosis, and management of disorders involving the immune system. Select…
    363A00000XPhysician AssistantA physician assistant is a person who has successfully completed an accredited education program for physician assistant, is licensed by the state and…
    207RP1001XPulmonary Disease PhysicianAn internist who treats diseases of the lungs and airways. The pulmonologist diagnoses and treats cancer, pneumonia, pleurisy, asthma, occupational an…
    207LP3000XPediatric Anesthesiology PhysicianAn anesthesiologist who has had additional skill and experience in and is primarily concerned with the anesthesia, sedation, and pain management needs…
    133VN1501XSports Dietetics Nutrition Registered DietitianAn individual who is a Board Certified Specialist in Sports Dietetics and applies evidence-based nutrition knowledge in exercise and sports. RDNs spec…

    Related ICD-10-CM Codes

    26 rows

    ICD-10-CM CodeDescription
    C64.9Malignant neoplasm of unspecified kidney, except renal pelvis
    C67.9Malignant neoplasm of bladder, unspecified
    D41.4Neoplasm of uncertain behavior of bladder
    N13.2Hydronephrosis with renal and ureteral calculous obstruction
    N13.6Pyonephrosis
    N20.0Calculus of kidney
    N20.1Calculus of ureter
    N20.2Calculus of kidney with calculus of ureter
    N21.0Calculus in bladder
    N21.1Calculus in urethra

    Showing 1–10 of 26

    Related Payer Policy Updates

    Specialty: Anesthesiology1 / 3

    9 rows

    PolicyPayerEffective Date
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Elective Inpatient Services (for Idaho Only)UnitedHealthcare2026-06-01
    Sites of Servicepriority health2026-06-01
    Coverage for Ambulatory Surgery Unit (ASU)/Outpatient Facility and Anesthesia for Dental Servicesuniverahealthcare2026-05-21
    Mm_0579_Coveragepositioncriteria_Anesthesia_Services_Selected_Nerve_BlocksCigna2026-05-15
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric DisordersBlue Cross Blue Shield - North Carolina2026-04-01

    Related Codes

    CPT-52320-CYSTOURETHROSCOPY-URETERAL-STONE-REMOVAL

    CPT 52320: Cystourethroscopy with Ureteral Stone Removal

    CPT-52325-URETERAL-LITHOTRIPSY-CYSTOURETHROSCOPY

    CPT 52325: Cystourethroscopy with Ureteral Stone Fragmentation and Removal

    CPT-52327-CYSTOURETHROSCOPY-SUBURETERAL-IMPLANT-INJECTION-FOR-VUR

    CPT 52327: Cystourethroscopy with Ureteral Submucosal Injection

    CPT-52330-CYSTOURETHROSCOPY-URETERAL-STONE-MANIPULATION

    CPT 52330: Cystourethroscopy with Ureteral Stone Manipulation

    CPT-52332-CYSTOURETHROSCOPY-URETERAL-STENT-PLACEMENT

    CPT 52332: Cystourethroscopy with Ureteral Stent Placement

    CPT-52334-CYSTOURETHROSCOPY-PERCUTANEOUS-RETROGRADE-NEPHROSTOMY

    CPT 52334: Cystourethroscopy with Guidewire for Retrograde Nephrostomy

    CPT-52341-CYSTOURETHROSCOPY-URETERAL-STRICTURE-TREATMENT

    CPT 52341: Cystourethroscopy with Ureteral Stricture Treatment

    CPT-52342-CYSTOURETHROSCOPY-WITH-URETERAL-CATHETER-TO-UPJ-FOR-UPJ-STRICTURE-TREATMENT

    CPT 52342: Cystourethroscopy with Ureteral Catheterization and UPJ Stricture Treatment

    CPT-52343-CYSTOURETHROSCOPY-WITH-INTRARENAL-STRICTURE-TREATMENT

    CPT 52343: Cystourethroscopy with Intrarenal Stricture Treatment

    CPT-52344-CYSTOURETHROSCOPY-URETERAL-STRICTURE-TREATMENT-URETEROSCOPY

    CPT 52344: Cystourethroscopy with Ureteral Stricture Treatment and Ureteroscopy

    Showing 1–10 of 17

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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