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    v1.0.30
    OpenPayerBilling CodesUreter and Pelvis Transurethral Surgical ProceduresCPT cpt-52334-cystourethroscopy-percutaneous-retrograde-nephrostomy
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    CPT 52334: Cystourethroscopy with Guidewire for Retrograde Nephrostomy

    Medicare pays $166 on average nationally for this procedure.

    CPT code 52334 describes a cystourethroscopy procedure in which a cystoscope is passed through the urethra to inspect the bladder, urethra, prostatic urethra, and ureteric orifices, and a guidewire is inserted through the ureter to establish a percutaneous retrograde nephrostomy (an artificial tract for renal pelvis drainage or stone removal); this service is a endoscopic cystourethroscopy with guidewire-assisted creation of a percutaneous retrograde nephrostomy typically performed in an operating room or procedure suite under appropriate anesthesia for urologic procedures involving the upper urinary tract.

    For related coverage guidance, see recent payer policy updates: Dental Anesthesia Services, Anesthesia Services for Interventional Pain Management Procedures in an Adult, General Anesthesia and Conscious Sedation Services.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is a 55-year-old male with recurrent obstructive nephrolithiasis and hydronephrosis refractory to conservative management who presents with flank pain and rising serum creatinine. Imaging (non-contrast CT or renal ultrasound) demonstrates a proximal ureteral stone with upstream dilation. The urology team elects to perform cystourethroscopy with retrograde ureteral access and placement of a guidewire to establish a percutaneous retrograde nephrostomy tract for drainage and/or staged stone removal.

    The clinical workflow: preoperative assessment includes history, focused genitourinary exam, coagulation review, and informed consent. In the OR or interventional suite under general or monitored anesthesia care, the surgeon performs a 52334 cystourethroscopy to inspect the urethra, prostatic urethra, bladder, and ureteral orifices. A guidewire is advanced through the ureteral orifice into the renal collecting system to facilitate percutaneous retrograde nephrostomy creation. The guidewire can be used by interventional radiology or urology to place a nephrostomy tube, facilitate antegrade/retrograde combined stone removal, or allow drainage in obstructive uropathy. Postprocedure includes imaging confirmation of access, dressing/nephrostomy management, pain control, and outpatient follow-up for definitive stone treatment or nephrostomy removal.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    52000Cystourethroscopy, with or without collection of specimen(s) by brushing or washing, with or without culture(s)Performed when diagnostic cystourethroscopy is done without ureteral instrumentation; may be billed when limited inspection and urine collection occur separate from retrograde nephrostomy access.
    52005Cystourethroscopy, with ureteroscopy and/or pyeloscopy; diagnosticMay be performed if diagnostic ureteroscopy of the ureter/renal pelvis is done in addition to cystoscopic inspection prior to guidewire placement.
    52010Cystourethroscopy, with ureteroscopy, with removal of small ureteral stone by basket or forcepsBilled when ureteroscopic stone removal is performed in the same session following retrograde access.
    50605Pyelostomy or nephrostomy, percutaneous, with dilatation and/or internal stent placement (indwelling)May be performed subsequently by interventional radiology or urology to place a nephrostomy tube after guidewire access is obtained via 52334.
    50080Percutaneous nephrostolithotomy; single access, including dilation and removal of stonesRepresents definitive percutaneous stone removal that may follow establishment of retrograde nephrostomy access via 52334.

    Related Modifiers

    11 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    63Modifier‑63 is appended to surgical CPT codes (20000–69990) when a procedure is performed on a neonate or infant weighing ≤ 4 kg (about 8.8 lbs). The AMA/AAPC definition specifies this use and notes…- Use modifier -63 only for surgical procedures in the CPT 20000–69990 series performed on a neonate or infant who weighs ≤ 4 kg at the time of the procedure; it indicates increased complexity due to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…

    Showing 1–10 of 11

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    208VP0000X
    208D00000X
    363L00000X
    283XC2000X
    225XF0002X
    2083A0300X
    246RM2200X
    163WN0300X

    Related ICD-10-CM Codes

    28 rows

    ICD-10-CM CodeDescription
    N10Acute pyelonephritis
    N11.0Nonobstructive reflux-associated chronic pyelonephritis
    N11.1Chronic obstructive pyelonephritis
    N11.9Chronic tubulo-interstitial nephritis, unspecified
    N12Tubulo-interstitial nephritis, not specified as acute or chronic
    N13.6Pyonephrosis
    N13.8Other obstructive and reflux uropathy
    N20.0Calculus of kidney
    N20.1Calculus of ureter
    N20.2Calculus of kidney with calculus of ureter

    Showing 1–10 of 28

    Related Payer Policy Updates

    Specialty: Anesthesiology1 / 3

    10 rows

    PolicyPayerEffective Date
    Dental Anesthesia ServicesProvidence Health Plan2026-10-01
    Anesthesia Services for Interventional Pain Management Procedures in an AdultCigna2026-09-15
    General Anesthesia and Conscious Sedation ServicesUnitedHealthcare2026-09-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Elective Inpatient Services (for Idaho Only)UnitedHealthcare2026-06-01
    Sites of Servicepriority health2026-06-01
    Coverage for Ambulatory Surgery Unit (ASU)/Outpatient Facility and Anesthesia for Dental Servicesuniverahealthcare2026-05-21

    Related Codes

    CPT-52320-CYSTOURETHROSCOPY-URETERAL-STONE-REMOVAL

    CPT 52320: Cystourethroscopy with Ureteral Stone Removal

    CPT-52325-URETERAL-LITHOTRIPSY-CYSTOURETHROSCOPY

    CPT 52325: Cystourethroscopy with Ureteral Stone Fragmentation and Removal

    CPT-52327-CYSTOURETHROSCOPY-SUBURETERAL-IMPLANT-INJECTION-FOR-VUR

    CPT 52327: Cystourethroscopy with Ureteral Submucosal Injection

    CPT-52330-CYSTOURETHROSCOPY-URETERAL-STONE-MANIPULATION

    CPT 52330: Cystourethroscopy with Ureteral Stone Manipulation

    CPT-52332-CYSTOURETHROSCOPY-URETERAL-STENT-PLACEMENT

    CPT 52332: Cystourethroscopy with Ureteral Stent Placement

    CPT-52341-CYSTOURETHROSCOPY-URETERAL-STRICTURE-TREATMENT

    CPT 52341: Cystourethroscopy with Ureteral Stricture Treatment

    CPT-52342-CYSTOURETHROSCOPY-WITH-URETERAL-CATHETER-TO-UPJ-FOR-UPJ-STRICTURE-TREATMENT

    CPT 52342: Cystourethroscopy with Ureteral Catheterization and UPJ Stricture Treatment

    CPT-52343-CYSTOURETHROSCOPY-WITH-INTRARENAL-STRICTURE-TREATMENT

    CPT 52343: Cystourethroscopy with Intrarenal Stricture Treatment

    CPT-52344-CYSTOURETHROSCOPY-URETERAL-STRICTURE-TREATMENT-URETEROSCOPY

    CPT 52344: Cystourethroscopy with Ureteral Stricture Treatment and Ureteroscopy

    CPT-52345-CYSTOURETHROSCOPY-URETEROSCOPIC-TREATMENT-UPJ-STRICTURE

    CPT 52345: Cystourethroscopy with Ureteroscopic UPJ Stricture Treatment

    Showing 1–10 of 17

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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