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    v1.0.28
    OpenPayerBilling CodesUrethra and Bladder Transurethral Surgical ProceduresCPT cpt-52285-cystourethroscopy-bladder-urethra-ureteric-openings-female-urethral-syndrome
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    CPT 52285: Cystourethroscopy and Treatment for Female Urethral Syndrome

    Medicare pays $336 on average nationally for this procedure.

    CPT code 52285 describes cystourethroscopy with inspection of the bladder, urethra, and ureteric orifices using a cystoscope passed through the urethra and includes treatment for female urethral syndrome using a variety of endoscopic or local methods; service type: endoscopic diagnostic and therapeutic procedure; typical site of service: ambulatory surgery center or hospital outpatient department or urology clinic performing cystoscopic procedures.

    For related coverage guidance, see recent payer policy updates: Prolonged Services for Labor Management, Prolonged Services for Labor Management, Cervical Cancer Screening.

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    Table of contents

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    • Billing CodesCPT, HCPCS, DRG & more
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    Clinical & Coding Specifications

    Clinical Context

    A 46-year-old female presents to the urology clinic with a 6-month history of recurrent dysuria, urinary frequency, and episodic urethral pain unresponsive to empirical oral antibiotics. After initial evaluation including urinalysis, urine culture, pelvic exam, and conservative measures, the urologist recommends diagnostic and therapeutic cystourethroscopy with targeted treatment for suspected female urethral syndrome. The procedure is scheduled in an ambulatory surgery center. Under monitored anesthesia care, a rigid or flexible cystoscope is passed through the urethra into the bladder for direct visualization of the urethra, bladder trigone, and ureteric orifices. Findings may include urethral inflammation, mucosal webs, or periurethral diverticula; the provider may perform local urethral dilation, topical steroid injection, fulguration of small lesions, or mechanical disruption of mucosal abnormalities during the same session. Post-procedure, the patient is observed in PACU and discharged with bladder care instructions and short-term analgesia if needed.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    52000Cystourethroscopy, diagnostic; with or without collection of specimen(s) by brushing or washingBasic diagnostic cystourethroscopy often performed as an initial exam and may precede therapeutic maneuvers coded with 52285.
    52287Cystourethroscopy, with ureteroscopy and/or pyeloscopy, including endoscopic removal of ureteral calculusPerformed if ureteral involvement or ureteral stones are identified during cystoscopy and require endoscopic treatment.
    52224Cystourethroscopy with biopsy of bladder or urethral lesion(s)Performed when suspicious mucosal lesions are encountered requiring tissue diagnosis during the same session.
    51702Irrigation of bladder, simple; for postoperative bladder irrigationMay be used post-procedure if bladder irrigation is necessary for clot or debris management.
    52214Cystourethroscopy with urethral dilation (therapeutic)Used when formal dilation of urethral stricture is performed as a separate documented therapeutic procedure.

    Related Modifiers

    10 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    77Modifier 77 indicates that a previously performed procedure or service was legitimately repeated by a different physician or other qualified health care professional. The AMA’s CPT definition…- Use modifier 77 when a basic procedure or service already performed is repeated by a different physician or other qualified health care professional (for example, a second provider independently…
    73Modifier 73 indicates a facility-level outpatient hospital or ASC procedure that was discontinued after the patient was prepared and taken to the procedure/operating room but before any anesthesia…- When to use: Apply CPT modifier 73 on the FACILITY (outpatient hospital or ASC) claim when the patient has been fully prepared and physically taken into the procedure/operating room but the…

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    208800000XUrology PhysicianA urologist manages benign and malignant medical and surgical disorders of the genitourinary system and the adrenal gland. This specialist has compreh…
    207RC0000XCardiovascular Disease PhysicianAn internist who specializes in diseases of the heart and blood vessels and manages complex cardiac conditions such as heart attacks and life-threaten…
    363L00000XNurse Practitioner(1) A registered nurse provider with a graduate degree in nursing prepared for advanced practice involving independent and interdependent decision mak…
    364S00000XClinical Nurse SpecialistA registered nurse who, through a graduate degree program in nursing, or through a formal post-basic education program or continuing education courses…
    227800000XCertified Respiratory TherapistA Certified Respiratory Therapist (CRT) is a an entry level therapist who has passed a standardized written examination administered by the National B…
    2278P1006XPulmonary Function Technologist Certified Respiratory TherapistAn individual who is trained and qualified to perform pulmonary diagnostic tests. In the course of conducting these tests, the Pulmonary Function Tec…
    251C00000XDevelopmentally Disabled Services Day Training AgencyThese agencies are authorized to provide day habilitation services to developmentally disabled individuals who live in their homes. The function of d…
    364SP0809XAdult Psychiatric/Mental Health Clinical Nurse SpecialistPhysician Assistants & Advanced Practice Nursing Providers · Clinical Nurse Specialist

    Related ICD-10-CM Codes

    30 rows

    ICD-10-CM CodeDescription
    C67.9Malignant neoplasm of bladder, unspecified
    D72.829Elevated white blood cell count, unspecified
    N10Acute pyelonephritis
    N12Tubulo-interstitial nephritis, not specified as acute or chronic
    N13.30Unspecified hydronephrosis
    N13.6Pyonephrosis
    N20.0Calculus of kidney
    N20.1Calculus of ureter
    N30.00Acute cystitis without hematuria
    N30.01Acute cystitis with hematuria

    Showing 1–10 of 30

    Related Payer Policy Updates

    Specialty: Obstetrics/Gynecology1 / 2

    8 rows

    PolicyPayerEffective Date
    Prolonged Services for Labor ManagementPremera Bluecross2027-01-01
    Prolonged Services for Labor ManagementPremera Bluecross2027-01-01
    Cervical Cancer ScreeningOscar Health2026-10-01
    Prenatal Testing for Fetal AneuploidyOscar Health2026-10-01
    Diagnosis of VaginitisOscar Health2026-10-01
    Prenatal Screening (Nongenetic)Oscar Health2026-10-01
    View PDF of Maternal Serum Biomarkers for Prediction of Adverse Obstetric Outcomes, Effective 10/1/2026 in MedicalBlue Cross Blue Shield - Rhode Island2026-10-01
    Maternal Serum Testing for Prediction of Adverse Obstetric OutcomesBluecross Idaho2026-09-01

    Related Codes

    CPT-52204-CYSTOURETHROSCOPY-WITH-BIOPSY

    CPT 52204: Cystourethroscopy with Biopsy

    CPT-52214-TRANSURETHRAL-BLADDER-URETHRAL-TISSUE-DESTRUCTION

    CPT 52214: Endoscopic Destruction of Bladder/Urethral Tissue

    CPT-52224-CYSTOSCOPY-LESION-DESTRUCTION-MINOR

    CPT 52224: Cystoscopy with Destruction of Minor Bladder Lesion

    CPT-52234-CYSTOSCOPIC-DESTRUCTION-SMALL-BLADDER-LESION

    CPT 52234: Cystoscopy with Destruction of Small Bladder Lesion

    CPT-52235-CYSTOSCOPIC-DESTRUCTION-MEDIUM-BLADDER-LESION-2-5CM

    CPT 52235: Cystoscopy with Fulguration of Medium Bladder Lesion

    CPT-52240-CYSTOSCOPY-LESION-FULGURATION-ABLATION-GREATER-THAN-5CM

    CPT 52240: Cystoscopy with Destruction of Bladder Lesion (>5.0 cm)

    CPT-52250-CYSTOSCOPIC-INTRAVESICAL-RADIOACTIVE-THERAPY-FOR-BLADDER-CANCER

    CPT 52250: Cystoscopy with Intravesical Radioisotope Therapy

    CPT-52260-DIAGNOSTIC-CYSTOSCOPY-INTERSTITIAL-CYSTITIS-EVALUATION

    CPT 52260: Cystoscopic Inspection Under Anesthesia for Interstitial Cystitis

    CPT-52265-DIAGNOSTIC-CYSTOSCOPY-INTERSTITIAL-CYSTITIS-EVALUATION

    CPT 52265: Diagnostic Cystoscopy for Interstitial Cystitis

    CPT-52270-CYSTOSCOPIC-URETHROTOMY-INTERNAL-URETHRAL-STRICTURE

    CPT 52270: Cystoscopy with Incision of Internal Urethral Stricture (Female)

    Showing 1–10 of 26

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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