CPT code 52240 designates a diagnostic cystoscopy combined with destructive treatment (fulguration or ablation) of bladder or urethral lesions larger than 5.0 cm using electrosurgery, cryotherapy, or laser. This code captures a bundled endoscopic inspection plus active lesion destruction and is relevant nationally because it affects billing for urologic tumor and lesion management in outpatient surgical settings. Proper use of the code influences reporting, reimbursement, and quality measurement for procedures addressing large bladder lesions.

Key payers covered in this analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. The publication outlines how CPT code 52240 is defined, typical clinical scenarios for its use, and the usual sites of service where it is performed. Readers will find a concise clinical context describing the procedure, benchmarking considerations for common payers, and notes on coding boundaries and related service definitions. Where payer‑specific policies or coverage rules apply, readers will receive an overview of the common commercial and federal payer perspectives. Data not available in the input are noted where applicable.