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    v1.0.30
    OpenPayerBilling CodesEndoscopy Procedures on the UreterCPT cpt-50955-endoscopic-ureteral-biopsy-via-established-tract
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    CPT 50955: Endoscopic Biopsy of Ureter via Established Tract

    Medicare pays $455 on average nationally for this procedure.

    CPT code 50955 describes an endoscopic biopsy of the kidney, renal pelvis, and ureter performed through an established skin-to-ureter tract for diagnosis of ureteral lesions; this procedure is a endoscopic urologic biopsy typically performed as an operative/interventional service in an ambulatory surgery center or hospital operating room using a ureteroscope passed via a preexisting percutaneous or cutaneous-ureteral access tract to obtain tissue for pathologic evaluation.

    For related coverage guidance, see recent payer policy updates: Diabetic Supplies, Radiofrequency Ablation for Thyroid Nodules, Continuous Glucose Monitoring and Insulin Delivery for Managing Diabetes (for Idaho Only).

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    Table of contents

    Progress1 / 7

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    Clinical & Coding Specifications

    Clinical Context

    A 62-year-old patient with a history of intermittent, painless gross hematuria and an indwelling ureteral stent presents for evaluation of a suspicious ureteral lesion identified on CT urogram. The urologist performs a ureteroscopy through a previously created percutaneous nephrostomy-to-ureter tract to visualize the renal pelvis and ureter and obtain targeted biopsies of the lesion under endoscopic guidance. The patient is brought to an ambulatory surgical center or hospital procedure suite, placed under general or regional anesthesia, and positioned for endoscopic access. The provider inspects the kidney, renal pelvis, and ureter through the existing skin-to-ureter tract, identifies the lesion, obtains tissue with biopsy forceps, and submits specimens for pathology. Hemostasis is confirmed and the nephrostomy or stent is managed per intraoperative findings. Typical documentation includes preoperative diagnosis, indication for biopsy, description of the established tract, anesthesia type, findings, number and site of biopsies, specimen labeling, complications (if any), and disposition.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    50080Insertion of non-tunneled external drainage catheter (e.g., nephrostomy)Often performed prior to or in conjunction with procedures that create or maintain a skin-to-ureter tract used for access.

    52000 | Cystourethroscopy, diagnostic; with or without collection of specimen(s) by brushing or washing | May be performed as an initial diagnostic endoscopic evaluation of the bladder and ureteral orifices before ureteroscopic biopsy.

    52332 | Cystourethroscopy with ureteroscopy, with or without irrigation, diagnostic | Frequently used when endoscopic inspection of the ureter is performed retrograde prior to percutaneous or through-tract biopsy.

    50590 | Lithotripsy, extracorporeal shock wave (ESWL) or percutaneous nephrolithotomy CPT-coded alternative procedures | Included when stone disease management and access to the renal collecting system overlap with procedures using an established tract.

    52315 | Cystourethroscopy with ureteroscopy and removal of foreign body, calculus or stent | May be performed before or after biopsy to manage stents or obstructing material encountered during the procedure.

    Related Modifiers

    10 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    56Modifier ‑56 indicates the reporting provider furnished only the preoperative management for a surgical procedure and did not perform the intraoperative or postoperative care. It is used in…- Use Modifier -56 when a provider performs only the preoperative management in a split‑care situation (one physician manages preop care while a different physician performs the intraoperative…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    208000000X
    363L00000X
    207L00000X
    207K00000X
    207PP0204X
    225XL0004X
    1223P0106X
    3416L0300X

    Related ICD-10-CM Codes

    27 rows

    ICD-10-CM CodeDescription
    C65.9Malignant neoplasm of unspecified renal pelvis
    C66.9Malignant neoplasm of unspecified ureter
    C67.9Malignant neoplasm of bladder, unspecified
    D41.4Neoplasm of uncertain behavior of bladder
    D41.9Neoplasm of uncertain behavior of unspecified urinary organ
    N12Tubulo-interstitial nephritis, not specified as acute or chronic
    N13.30Unspecified hydronephrosis
    N13.6Pyonephrosis
    N13.8Other obstructive and reflux uropathy
    N20.0Calculus of kidney

    Showing 1–10 of 27

    Related Payer Policy Updates

    Specialty: Endocrinology1 / 3

    10 rows

    PolicyPayerEffective Date
    Diabetic SuppliesCigna2026-10-15
    Radiofrequency Ablation for Thyroid NodulesCigna2026-10-15
    Continuous Glucose Monitoring and Insulin Delivery for Managing Diabetes (for Idaho Only)UnitedHealthcare2026-10-01
    Tzield (teplizumab-mzwv) CoverageUnitedHealthcare2026-10-01
    Continuous Glucose Monitoring and Insulin Delivery for Managing Diabetes (for Indiana Only)UnitedHealthcare2026-10-01
    Medical Necessity Guidelines Insulin PumpsMass General Brigham Health Plan2026-10-01
    Medical Necessity Guidelines: Continuous Glucose MonitorsMass General Brigham Health Plan2026-10-01
    Continuous Glucose MonitoringAmbetter Nevada2026-10-01
    Salivary Hormone TestingOscar Health2026-10-01
    Bone Turnover Markers TestingOscar Health2026-10-01

    Related Codes

    CPT-50951-PERCUTANEOUS-URETEROSCOPY-URETERAL-STONE-REMOVAL

    CPT 50951: Percutaneous Nephroscopy/Ureteroscopy for Stone Evaluation and Removal

    CPT-50953-PERCUTANEOUS-URETEROSCOPIC-EXAMINATION-CATHETERIZATION

    CPT 50953: Endoscopic Exam via Cutaneous Ureteral Tract

    CPT-50957-PERCUTANEOUS-ENDOSCOPIC-RENAL-URETEROSCOPIC-PROCEDURE-MALIGNANCY

    CPT 50957: Endoscopic Exam via Cutaneous Ureterostomy for Biopsy/Destruction

    CPT-50961-PERCUTANEOUS-ENDOSCOPIC-URETERAL-STONE-REMOVAL

    CPT 50961: Percutaneous Ureteroscopy via Existing Skin-Ureter Tract

    CPT-50970-URETEROSCOPIC-EXAMINATION-AND-STONE-REMOVAL

    CPT 50970: Ureteroscopy with Ureterotomy for Ureteral Stone Removal

    CPT-50972-URETEROSCOPY-URETEROTOMY-FOR-STONE-REMOVAL

    CPT 50972: Ureteroscopy with Ureteral Endoscopy for Stone Removal

    CPT-50974-URETEROSCOPIC-KIDNEY-RENAL-PELVIS-URETER-BIOPSY-STONE-REMOVAL

    CPT 50974: Ureteroscopy with Biopsy and Ureteral Stone Removal

    CPT-50976-URETEROSCOPIC-EXAMINATION-BIOPSY-FULGURATION

    CPT 50976: Ureteroscopy with Biopsy and Tissue Destruction

    CPT-50980-URETEROSCOPY-WITH-URETEROTOMY-AND-STONE-REMOVAL

    CPT 50980: Ureteroscopy with Inspection and Stone Removal

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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