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    OpenPayerBilling CodesEndoscopy Procedures on the KidneyCPT cpt-50557-endoscopic-renal-procedure-tissue-destruction-incision
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    CPT 50557: Percutaneous Nephroscopy With Tissue Destruction/Incision

    Medicare pays $448 on average nationally for this procedure.

    CPT code 50557 describes percutaneous nephroscopy through a previously established nephrostomy or renal pelvis opening in which an endoscope is inserted to inspect the kidney, renal pelvis, and ureter and to destroy or incise tissue; service type: percutaneous endoscopic kidney procedure; typical site of service: inpatient or outpatient hospital setting or ambulatory surgery center, performed through an existing external renal collecting-system access point.

    For related coverage guidance, see recent payer policy updates: Vafseo (vadadustat) for anemia in CKD on dialysis, Metabolic Disorders - Cysteamine (Oral) Products for Individual and Family Plans, Kerendia (finerenone) — Coverage Criteria.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is a 58-year-old with recurrent flank pain and hematuria found to have obstructing renal calculi within a previously created nephrostomy tract or percutaneous renal access. The patient presents to interventional urology/radiology for percutaneous nephroscopy via a previously established tract to visualize the renal collecting system, evaluate the renal pelvis and ureter, and perform tissue destruction or incision (for example, laser lithotripsy of stones, fulguration of tumor, or incision of strictures). The clinical workflow includes pre-procedure imaging review (CT urogram or renal ultrasound), informed consent, review of coagulation status and antibiotics, placement and confirmation of access through the existing nephrostomy or tract, endoscopic inspection of the kidney and pelvis, targeted destruction/incision of pathology using electrocautery or laser, retrieval of stone fragments or biopsy/tissue management as indicated, hemostasis confirmation, and post-procedure monitoring with plans for drainage catheter management or staged interventions as needed. Typical settings are hospital operating room, ambulatory surgical center, or interventional radiology suite when performed using a previously established percutaneous renal access.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    50390Nephrostomy, placement, percutaneous, with pyelography, with or without catheter or tube; initial placementOften performed before or in conjunction with establishing percutaneous access for later nephroscopy via a mature tract.
    50590Pyelotomy, with or without drainage, for removal of stone, with or without insertion of stent or tubeRelated open or percutaneous stone removal procedures that may be alternative or adjunctive to endoscopic destruction.
    52310Cystourethroscopy, with or without irrigation and instillation; diagnostic, with or without collection of specimen(s) by brushing or washingCystoscopic evaluation and ureteral catheterization may be performed before or after nephroscopy to manage ureteral components.
    52000Cystourethroscopy, with or without collection of specimen(s) by brushing or washing (separate diagnostic cystoscopy)Diagnostic lower tract endoscopy that can be part of the broader urologic workup.
    55866Laparoscopy, surgical, with cryoablation or other destruction of renal tumor, unilateralAlternative method for renal tumor destruction when percutaneous endoscopic approach is not appropriate.
    50700Nephrostomy, percutaneous, with placement of indwelling catheterOften part of initial drainage management and may be present as the previously established opening used for 50557.

    Related Modifiers

    11 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…
    81Modifier -81 indicates a physician served as a minimal assistant surgeon for part—not all—of an operative procedure. Use when a physician’s assisting role is limited and does not represent full…- Use CPT modifier -81 when a physician acts as a minimum assistant surgeon who assists during only part (a limited portion) of an operative procedure; append -81 to the primary surgical CPT code to…

    Showing 1–10 of 11

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    208100000X
    208D00000X
    174400000X
    363L00000X
    363A00000X
    207QH0002X
    251S00000X
    332BP3500X

    Related Payer Policy Updates

    Specialty: Nephrology1 / 2

    10 rows

    PolicyPayerEffective Date
    Vafseo (vadadustat) for anemia in CKD on dialysisCigna2026-08-15
    Metabolic Disorders - Cysteamine (Oral) Products for Individual and Family PlansCigna2026-08-15
    Kerendia (finerenone) — Coverage CriteriaBlue Cross Blue Shield - Iowa2026-08-05
    Voyxact (sibeprenlimab-szsl) — Prior authorization / medical necessity for primary IgA nephropathyColorado Rocky Mountain Health Plans2026-08-01
    Oxlumo (lumasiran) and Rivfloza (nedosiran) — Coverage Criteria (Ohio)Colorado Rocky Mountain Health Plans2026-08-01
    Korsuva (difelikefalin) — Medical Benefit Drug Coverage Criteria (Ohio)Colorado Rocky Mountain Health Plans2026-08-01
    Complement Inhibitors - EmpaveliCigna2026-08-01
    Tolvaptan (Jynarque)Cigna2026-08-01
    Nephrology - Filspari (sparsentan) coverageCigna2026-08-01
    Rivfloza (nedosiran) prior authorization for PH1UnitedHealthcare2026-08-01

    Related Codes

    CPT-50551-ENDOSCOPIC-EXAMINATION-KIDNEY-RENAL-PELVIS-URETER

    CPT 50551: Endoscopic Examination of Kidney via Existing Nephrostomy

    CPT-50553-ENDOSCOPIC-EXAMINATION-KIDNEY-RENAL-PELVIS-CATHETER

    CPT 50553: Nephroscopy Through Established Percutaneous/Pyelostomy Tract

    CPT-50555-RENAL-ENDOSCOPY-PYELOSCOPIC-BIOPSY

    CPT 50555: Nephroscopy with Biopsy via Established Access

    CPT-50561-PERCUTANEOUS-RENAL-ENDOSCOPY-STONE-FOREIGN-BODY-REMOVAL

    CPT 50561: Percutaneous Nephroscopy with Stone/Foreign Body Removal

    CPT-50562-ENDOSCOPIC-RENAL-TUMOR-REMOVAL

    CPT 50562: Nephroscopy With Tumor Removal

    CPT-50570-PERCUTANEOUS-ENDOSCOPIC-RENAL-VISUALIZATION

    CPT 50570: Nephrostomy with Endoscopic Evaluation

    CPT-50572-ENDOSCOPIC-EXAMINATION-KIDNEY-RENAL-PELVIS-URETER

    CPT 50572: Nephrostomy Endoscope Examination of Kidney and Renal Pelvis

    CPT-50574-PERCUTANEOUS-ENDOSCOPIC-RENAL-EVALUATION-BIOPSY

    CPT 50574: Endoscopic Examination of Kidney with Biopsy

    CPT-50575-ANTEGRADE-ENDOPYELOTOMY-UPJ-STRICTURE

    CPT 50575: Antegrade Endopyelotomy for UPJ Stricture

    CPT-50576-ENDOSCOPIC-RENAL-PELVIS-EVALUATION-BIOPSY-ABLATION

    CPT 50576: Percutaneous Nephroscopy with Biopsy and Ablation

    Showing 1–10 of 11

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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