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    v1.0.30
    OpenPayerBilling CodesRepair Procedures on the KidneyCPT cpt-50435-percutaneous-nephrostomy-catheter-exchange-image-guidance
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    CPT 50435: Percutaneous Nephrostomy Catheter Exchange with Imaging

    Medicare pays $588 on average nationally for this procedure.

    CPT code 50435 describes percutaneous nephrostomy catheter exchange using real-time imaging (ultrasound and/or fluoroscopy) to replace or reposition a nephrostomy catheter and divert urine due to obstruction, with optional contrast injection for nephrostogram and ureterogram; service type: image-guided interventional radiology procedure; typical site of service: hospital outpatient radiology suite or interventional radiology lab, occasionally performed in ambulatory surgical centers when equipped for fluoroscopy/ultrasound and sterile percutaneous intervention.

    For related coverage guidance, see recent payer policy updates: Vafseo (vadadustat) for anemia in CKD on dialysis, Metabolic Disorders - Cysteamine (Oral) Products for Individual and Family Plans, Kerendia (finerenone) — Coverage Criteria.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 67-year-old male with a left-sided obstructing proximal ureteral stone presents with rising creatinine and flank pain. An interventional radiology consult is obtained for urgent urinary decompression. Under conscious sedation in the IR suite, the interventional radiologist uses ultrasound guidance to access the renal collecting system and places a percutaneous nephrostomy catheter. Fluoroscopy is used to exchange the existing nephrostomy catheter for a new catheter and to perform a nephrostogram with contrast to confirm catheter position and assess ureteral patency. The procedure includes real-time imaging, injection of contrast for nephrostogram/ureterogram, catheter manipulation and securement, and radiological supervision and interpretation.

    Typical clinical workflow:

    • Pre-procedure: History, anticoagulation review, informed consent, basic labs and coagulation status confirmed.

    • Procedure: Patient positioned in IR suite or procedure room; sterile technique; ultrasound and fluoroscopy used for access and catheter exchange; contrast injected for nephrostogram/ureterogram; catheter secured and dressing applied.

    • Post-procedure: Immediate fluoroscopic images reviewed; nephrostomy output monitored; post-procedure instructions provided; documentation includes image interpretation and procedural details.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    50432Percutaneous nephrostomy with catheter placement (initial placement)Often performed prior to or instead of an exchange when no existing catheter is in place; initial decompression procedure.
    50390Pyelostomy or nephrostomy, percutaneous, including injection for nephrostogram when performedRelated diagnostic/decompression procedure; may overlap in clinical scenarios involving nephrostomy placement and imaging.
    77002Fluoroscopic guidance for catheter placement (real-time)Represents the imaging guidance component frequently used during exchange procedures; technical component often bundled in primary code.
    74425Radiologic supervision and interpretation, retrograde or antegrade pyelographyUsed when detailed radiologic imaging of the collecting system or ureter is documented; nephrostogram/ureterogram interpretations may map here.
    50392Nephrostomy catheter removal, with or without contrast nephrostogramMay be performed during catheter exchange or removal events in the same episode of care.

    Related Modifiers

    10 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    77Modifier 77 indicates that a previously performed procedure or service was legitimately repeated by a different physician or other qualified health care professional. The AMA’s CPT definition…- Use modifier 77 when a basic procedure or service already performed is repeated by a different physician or other qualified health care professional (for example, a second provider independently…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207K00000X
    208D00000X
    207RP1001X
    364SR0400X
    1223D0004X
    163WN0800X
    207QG0300X
    261QG0250X

    Related ICD-10-CM Codes

    26 rows

    ICD-10-CM CodeDescription
    I12.9Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease
    I13.0Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease
    N10Acute pyelonephritis
    N11.1Chronic obstructive pyelonephritis
    N11.8Other chronic tubulo-interstitial nephritis
    N12Tubulo-interstitial nephritis, not specified as acute or chronic
    N13.30Unspecified hydronephrosis
    N13.6Pyonephrosis
    N13.8Other obstructive and reflux uropathy
    N13.9Obstructive and reflux uropathy, unspecified

    Showing 1–10 of 26

    Related Payer Policy Updates

    Specialty: Nephrology1 / 3

    10 rows

    PolicyPayerEffective Date
    Vafseo (vadadustat) for anemia in CKD on dialysisCigna2026-08-15
    Metabolic Disorders - Cysteamine (Oral) Products for Individual and Family PlansCigna2026-08-15
    Kerendia (finerenone) — Coverage CriteriaBlue Cross Blue Shield - Iowa2026-08-05
    Voyxact (sibeprenlimab-szsl) — Prior authorization / medical necessity for primary IgA nephropathyColorado Rocky Mountain Health Plans2026-08-01
    Oxlumo (lumasiran) and Rivfloza (nedosiran) — Coverage Criteria (Ohio)Colorado Rocky Mountain Health Plans2026-08-01
    Korsuva (difelikefalin) — Medical Benefit Drug Coverage Criteria (Ohio)Colorado Rocky Mountain Health Plans2026-08-01
    Complement Inhibitors - EmpaveliCigna2026-08-01
    Tolvaptan (Jynarque)Cigna2026-08-01
    Nephrology - Filspari (sparsentan) coverageCigna2026-08-01
    Rivfloza (nedosiran) prior authorization for PH1UnitedHealthcare2026-08-01

    Related Codes

    CPT-50400-PYELOPLASTY-URETEROPELVIC-JUNCTION-REPAIR

    CPT 50400: Pyeloplasty, Ureteropelvic Junction Reconstruction

    CPT-50405-PYELOPLASTY-URETEROPELVIC-JUNCTION-RECONSTRUCTION

    CPT 50405: Pyeloplasty to Reconstruct Ureteropelvic Junction

    CPT-50430-PERCUTANEOUS-URETEROGRAM-NEPHROSTOGRAM-DIAGNOSTIC

    CPT 50430: Percutaneous Ureterogram/Nephrostogram with Contrast

    CPT-50431-NEPHROSTOGRAM-URETEROGRAM-CONTRAST-STUDY

    CPT 50431: Contrast Injection for Nephrostogram or Ureterogram

    CPT-50432-PERCUTANEOUS-NEPHROSTOMY-WITH-IMAGING-GUIDANCE

    CPT 50432: Percutaneous Nephrostomy Catheter Placement with Imaging

    CPT-50433-PERCUTANEOUS-NEPHROSTOMY-IMAGE-GUIDED-RENAL-DRAINAGE

    CPT 50433: Percutaneous Nephrostomy Catheter Placement

    CPT-50434-PERCUTANEOUS-NEPHROSTOMY-TO-NEPHROURETERAL-CONVERSION

    CPT 50434: Image-Guided Nephrostomy to Nephroureteral Catheter Conversion

    CPT-50500-KIDNEY-WOUND-SUTURE-REPAIR

    CPT 50500: Kidney Wound Suture

    CPT-50520-NEPHROCUTANEOUS-PYELOCUTANEOUS-FISTULA-CLOSURE

    CPT 50520: Nephrocutaneous and Pyelocutaneous Fistula Closure

    CPT-50525-RENAL-FISTULA-CLOSURE-ABDOMINAL-APPROACH

    CPT 50525: Closure of Renal Fistula, Abdominal Approach

    Showing 1–10 of 12

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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