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    OpenPayerBilling CodesRepair Procedures on the KidneyCPT cpt-50405-pyeloplasty-ureteropelvic-junction-reconstruction
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    CPT 50405: Pyeloplasty to Reconstruct Ureteropelvic Junction

    Medicare pays $1264 on average nationally for this procedure.

    CPT code 50405 describes a pyeloplasty, a surgical reconstruction procedure to correct an obstruction between the renal pelvis and the ureter; the service is an open surgical reconstructive procedure typically performed in an operating room setting at an inpatient or outpatient surgical facility such as a hospital or ambulatory surgery center.

    For related coverage guidance, see recent payer policy updates: Vafseo (vadadustat) for anemia in CKD on dialysis, Metabolic Disorders - Cysteamine (Oral) Products for Individual and Family Plans, Kerendia (finerenone) — Coverage Criteria.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is a 28–45-year-old adult presenting with flank pain, recurrent urinary tract infections, and/or impaired renal function attributed to ureteropelvic junction (UPJ) obstruction. Workup includes renal ultrasound demonstrating hydronephrosis, diuretic renal scintigraphy showing diminished drainage or differential renal function, and cross-sectional imaging (CT urogram or MR urogram) to define anatomy. After conservative measures or endoscopic attempts fail or when anatomical obstruction is severe, the urologist schedules a 50405 pyeloplasty. The procedure is most often performed in an inpatient or ambulatory surgical center operating room under general anesthesia. Typical workflow: preoperative evaluation and informed consent; anesthesia induction and patient positioning; exposure of the renal pelvis and proximal ureter via an open or minimally invasive approach; excision of the obstructed segment and reconstruction of the ureteropelvic junction with or without transposition of a crossing vessel; placement of a ureteral stent as indicated; intraoperative assessment of urine drainage; postoperative monitoring in PACU with pain control, urinary stent management, and imaging follow-up (renal ultrasound or diuretic renogram) to confirm improved drainage. Common perioperative providers include urologists (pediatric or adult), anesthesiologists, surgical nurses, and radiology for pre/post imaging.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    50400Repair of ureteropelvic junction; pyeloplasty, open approachClosely related alternative code representing open pyeloplasty technique; may be used when documentation specifies open versus reconstructive approach.
    50590Lithotripsy, extracorporeal shock wave (ESWL)Performed preoperatively or postoperatively for concurrent renal calculi that may contribute to obstruction.
    52000Cystourethroscopy, diagnostic, with or without collection of specimen(s)Used for diagnostic endoscopic evaluation of the bladder and ureteral orifice preoperatively or intraoperatively for stent placement.
    52332Cystourethroscopy; with ureteral stent placement (with or without cystoscopic removal)Used when intraoperative or postoperative stent placement is required as part of the pyeloplasty procedure.
    77850Radioisotope renal imaging; renal cortical imaging, including renal scan (e.g., MAG3 diuretic renogram)Common preoperative and postoperative functional assessment to document obstruction and improved drainage after 50405.
    49010Drainage of renal or perinephric abscess, open or percutaneousMay be performed prior to definitive pyeloplasty if infection or abscess complicates the clinical course.

    Related Modifiers

    10 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    208800000X
    208D00000X
    207L00000X
    208200000X
    208600000X
    335U00000X
    333600000X
    1223D0001X

    Related Payer Policy Updates

    Specialty: Nephrology1 / 2

    10 rows

    PolicyPayerEffective Date
    Vafseo (vadadustat) for anemia in CKD on dialysisCigna2026-08-15
    Metabolic Disorders - Cysteamine (Oral) Products for Individual and Family PlansCigna2026-08-15
    Kerendia (finerenone) — Coverage CriteriaBlue Cross Blue Shield - Iowa2026-08-05
    Voyxact (sibeprenlimab-szsl) — Prior authorization / medical necessity for primary IgA nephropathyColorado Rocky Mountain Health Plans2026-08-01
    Oxlumo (lumasiran) and Rivfloza (nedosiran) — Coverage Criteria (Ohio)Colorado Rocky Mountain Health Plans2026-08-01
    Korsuva (difelikefalin) — Medical Benefit Drug Coverage Criteria (Ohio)Colorado Rocky Mountain Health Plans2026-08-01
    Complement Inhibitors - EmpaveliCigna2026-08-01
    Tolvaptan (Jynarque)Cigna2026-08-01
    Nephrology - Filspari (sparsentan) coverageCigna2026-08-01
    Rivfloza (nedosiran) prior authorization for PH1UnitedHealthcare2026-08-01

    Related Codes

    CPT-50400-PYELOPLASTY-URETEROPELVIC-JUNCTION-REPAIR

    CPT 50400: Pyeloplasty, Ureteropelvic Junction Reconstruction

    CPT-50430-PERCUTANEOUS-URETEROGRAM-NEPHROSTOGRAM-DIAGNOSTIC

    CPT 50430: Percutaneous Ureterogram/Nephrostogram with Contrast

    CPT-50431-NEPHROSTOGRAM-URETEROGRAM-CONTRAST-STUDY

    CPT 50431: Contrast Injection for Nephrostogram or Ureterogram

    CPT-50432-PERCUTANEOUS-NEPHROSTOMY-WITH-IMAGING-GUIDANCE

    CPT 50432: Percutaneous Nephrostomy Catheter Placement with Imaging

    CPT-50433-PERCUTANEOUS-NEPHROSTOMY-IMAGE-GUIDED-RENAL-DRAINAGE

    CPT 50433: Percutaneous Nephrostomy Catheter Placement

    CPT-50434-PERCUTANEOUS-NEPHROSTOMY-TO-NEPHROURETERAL-CONVERSION

    CPT 50434: Image-Guided Nephrostomy to Nephroureteral Catheter Conversion

    CPT-50435-PERCUTANEOUS-NEPHROSTOMY-CATHETER-EXCHANGE-IMAGE-GUIDANCE

    CPT 50435: Percutaneous Nephrostomy Catheter Exchange with Imaging

    CPT-50500-KIDNEY-WOUND-SUTURE-REPAIR

    CPT 50500: Kidney Wound Suture

    CPT-50520-NEPHROCUTANEOUS-PYELOCUTANEOUS-FISTULA-CLOSURE

    CPT 50520: Nephrocutaneous and Pyelocutaneous Fistula Closure

    CPT-50525-RENAL-FISTULA-CLOSURE-ABDOMINAL-APPROACH

    CPT 50525: Closure of Renal Fistula, Abdominal Approach

    Showing 1–10 of 12

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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