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    OpenPayerBilling CodesIncision Procedures on the KidneyCPT cpt-50080-percutaneous-antegrade-renal-stone-removal-simple
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    CPT 50080: Percutaneous Nephrolithotomy, Antegrade Stone Removal (Simple)

    Medicare pays $640 on average nationally for this procedure.

    CPT code 50080 describes a simple percutaneous nephrolithotomy: removal of one or more stones from the kidney or renal pelvis using an antegrade percutaneous ("downhill") approach with imaging guidance, often performed with placement of a stent and/or nephrostomy tube; service type: procedural stone removal; typical site of service: hospital operating room or interventional radiology suite.

    For related coverage guidance, see recent payer policy updates: Surgical Procedures, Outpatient Surgical Procedures - Site of Service, Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in Adults.

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    Table of contents

    Progress1 / 7

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    Clinical & Coding Specifications

    Clinical Context

    A 54-year-old male presents with acute flank pain, hematuria, and imaging demonstrating a 1.8 cm obstructing renal pelvic stone in the right kidney with hydronephrosis. Conservative measures and extracorporeal shockwave lithotripsy were either contraindicated or unsuccessful. The urology team schedules a percutaneous antegrade stone removal under fluoroscopic and ultrasound guidance. In the procedural workflow the patient undergoes pre-procedure anesthesia evaluation (typically general or monitored anesthesia care), sterile percutaneous access to the renal collecting system is obtained, dilators and sheaths are placed, and the stone(s) are fragmented and removed through an antegrade tract. A ureteral stent and/or percutaneous nephrostomy tube may be placed at the conclusion for drainage. Post-procedure recovery includes monitoring for bleeding, infection, and urine output; analgesia; and an imaging or follow-up visit to assess stent or tube removal.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    50430Renal cortical biopsy, percutaneous, with imaging guidanceMay be performed for diagnostic evaluation in complex renal disease or prior to interventions affecting renal parenchyma; not routine with stone extraction.
    50590Lithotripsy, extracorporeal shock wave (ESWL)Often attempted prior to percutaneous approaches for suitable stones; alternative treatment modality.
    50960Nephrostomy, percutaneous or open, with closed drainage systemPlacement of a nephrostomy tube can occur before, during, or after percutaneous stone removal for drainage.
    52332Cystourethroscopy, with ureteroscopy and/or pyeloscopy, with removal of ureteral stone(s) intramural and/or ureteralAntegrade procedures may be combined or followed by retrograde ureteroscopy when fragments migrate or for staged management.
    50436Pyelolithotomy, percutaneous or open, with nephrolithotomyOpen or more complex percutaneous removals may use related codes when the procedure is more extensive than a simple antegrade removal.

    Related Modifiers

    13 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    58Modifier 58 (Staged or related procedure/service by the same physician during the postoperative period) indicates that a subsequent procedure performed by the same provider during the…- Use modifier 58 when the same physician/QHP performs a procedure during the postoperative/global period of an earlier procedure and the subsequent procedure is either planned or anticipated…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    63Modifier‑63 is appended to surgical CPT codes (20000–69990) when a procedure is performed on a neonate or infant weighing ≤ 4 kg (about 8.8 lbs). The AMA/AAPC definition specifies this use and notes…- Use modifier -63 only for surgical procedures in the CPT 20000–69990 series performed on a neonate or infant who weighs ≤ 4 kg at the time of the procedure; it indicates increased complexity due to…

    Showing 1–10 of 13

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    208U00000X
    208D00000X
    207R00000X
    363L00000X
    1835I0206X
    2278P3900X
    227800000X
    363LN0005X

    Related ICD-10-CM Codes

    26 rows

    ICD-10-CM CodeDescription
    E87.0Hyperosmolality and hypernatremia
    E87.1Hypo-osmolality and hyponatremia
    I12.9Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease
    N10Acute pyelonephritis
    N11.0Nonobstructive reflux-associated chronic pyelonephritis
    N11.1Chronic obstructive pyelonephritis
    N11.8Other chronic tubulo-interstitial nephritis
    N12Tubulo-interstitial nephritis, not specified as acute or chronic
    N13.2Hydronephrosis with renal and ureteral calculous obstruction
    N20.0Calculus of kidney

    Showing 1–10 of 26

    Related Payer Policy Updates

    Specialty: General Surgery1 / 2

    10 rows

    PolicyPayerEffective Date
    Surgical ProceduresUnitedHealthcare2026-09-01
    Outpatient Surgical Procedures - Site of ServiceUnitedHealthcare2026-09-01
    Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Site of Service for Ambulatory Surgical Procedures (ASC Select)Premera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Outpatient Surgical Procedures - Site of Servicesierra health and life2026-08-01
    Medical Necessity Guidelines — Inpatient Surgical CareMass General Brigham Health Plan2026-08-01
    Ambulatory Surgery Center (ASC) - Site of Care PolicyKaiser Permanente2026-08-01

    Related Codes

    CPT-50010-RENAL-DIAGNOSTIC-EXPLORATION-KIDNEY

    CPT 50010: Diagnostic Exploration of Kidney

    CPT-50020-OPEN-DRAINAGE-RENAL-PERIRENAL-ABSCESS

    CPT 50020: Open Drainage of Renal or Perirenal Abscess

    CPT-50040-CREATION-OF-RENAL-CUTANEOUS-FISTULA-NEPHROSTOMY

    CPT 50040: Open Nephrostomy for Urinary Obstruction

    CPT-50045-URINARY-OBSTRUCTION-RELIEF-SURGICAL-PROCEDURE

    CPT 50045: Surgical Relief of Urinary Tract Obstruction

    CPT-50060-SURGICAL-REMOVAL-KIDNEY-STONE

    CPT 50060: Surgical Removal of Kidney Stones (Nephrolithiasis)

    CPT-50065-NEPHROLITHOTOMY-SECONDARY-PROCEDURE-RENAL-STONE-REMOVAL

    CPT 50065: Nephrolithotomy for Kidney Stone Removal

    CPT-50070-KIDNEY-INCISION-STONE-REMOVAL-CONGENITAL-MALFORMATION

    CPT 50070: Nephrolithotomy for Renal Calculi with Kidney Malformation

    CPT-50075-OPEN-NEPHROLITHOTOMY-STAGHORN-CALCULUS-REMOVAL

    CPT 50075: Nephrolithotomy for Staghorn Renal Calculus

    CPT-50081-PERCUTANEOUS-ANTEGRADE-RENAL-URETERAL-STONE-REMOVAL-COMPLEX

    CPT 50081: Percutaneous Antegrade Removal of Kidney/Ureteral Stones

    CPT-50100-UPJ-REPAIR-RENAL-VESSEL-REPOSITIONING

    CPT 50100: Reposition/Incision of Aberrant Renal Vessels for UPJ Obstruction

    Showing 1–10 of 13

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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