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    OpenPayerBilling CodesIncision Procedures on the KidneyCPT cpt-50065-nephrolithotomy-secondary-procedure-renal-stone-removal
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    CPT 50065: Nephrolithotomy for Kidney Stone Removal

    Medicare pays $1096 on average nationally for this procedure.

    CPT code 50065 describes a nephrolithotomy performed as a secondary procedure to remove renal calculus (kidney stone); the service is a surgical stone removal typically performed in an operative setting such as an operating room or surgical suite and involves direct removal of accumulated mineral deposits from the kidney to restore urinary function.

    For related coverage guidance, see recent payer policy updates: Surgical Procedures, Outpatient Surgical Procedures - Site of Service, Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in Adults.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 52-year-old male presents with severe right-sided flank pain, hematuria, and recurrent urinary tract infections. Imaging (non-contrast CT KUB) demonstrates a 2.8 cm staghorn calculus occupying the renal pelvis and extending into multiple calyces of the right kidney. Conservative measures and less invasive stone removal attempts (extracorporeal shock wave lithotripsy and ureteroscopy) were unsuccessful due to stone size and location. The patient is scheduled for a percutaneous nephrolithotomy as a secondary corrective procedure to remove the calculus. The typical clinical workflow includes preoperative evaluation (labs, coagulation status, urine culture), informed consent, placement of the patient in prone or supine position in the operating room, percutaneous access to the renal collecting system under fluoroscopic and/or ultrasound guidance, tract dilation, fragmentation and extraction of stone fragments, placement of nephrostomy tube or ureteral stent as indicated, and postoperative monitoring with imaging and pain control. Usual sites of service are the hospital inpatient or outpatient surgical suite, and an ambulatory surgery center when appropriate.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    50590Lithotripsy, extracorporeal shock wave (ESWL)Often attempted prior to 50065 for renal calculi that are smaller or favorably located; may precede nephrolithotomy when ESWL fails.
    52332Cystourethroscopy, with ureteroscopy, with ureteral or renal pelvic stone removalEndoscopic approach that may be used as an alternative or adjunct to 50065 for stones accessible via the ureter.
    50960Nephrostomy, percutaneous, including imaging guidance; initial placementMay be performed preoperatively or postoperatively for drainage or as access for staged stone removal with 50065.
    50586Lithotripsy, percutaneous nephrostolithotomy; with renal endoscopy, including fragmentation and extractionRelated percutaneous stone procedure codes for nephrolithotomy variants and fragment removal techniques.
    58999Unlisted procedure, hemic, pelvis/renal areaUsed rarely for novel or unlisted renal stone procedures when no precise CPT exists, billed with appropriate documentation.

    Related Modifiers

    13 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    54Modifier ‑54 (“Surgical care only”) is appended to a CPT surgical procedure when the reporting surgeon performs the intraoperative (surgical) component but does not furnish the preoperative and/or…- Use modifier -54 when the reporting surgeon provided only the intraoperative (surgical) component of a procedure and preoperative and/or postoperative management has been or will be provided by…
    55Modifier –55 indicates the billing provider furnished only postoperative management for a procedure that has a global surgical period. According to AAPC, this modifier is appended to the same CPT…- Use modifier -55 when billing the same CPT surgical code that has a 10- or 90-day global period and you, as a provider other than the original surgeon, furnished ONLY postoperative management (no…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…
    73Modifier 73 indicates a facility-level outpatient hospital or ASC procedure that was discontinued after the patient was prepared and taken to the procedure/operating room but before any anesthesia…- When to use: Apply CPT modifier 73 on the FACILITY (outpatient hospital or ASC) claim when the patient has been fully prepared and physically taken into the procedure/operating room but the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…
    81Modifier -81 indicates a physician served as a minimal assistant surgeon for part—not all—of an operative procedure. Use when a physician’s assisting role is limited and does not represent full…- Use CPT modifier -81 when a physician acts as a minimum assistant surgeon who assists during only part (a limited portion) of an operative procedure; append -81 to the primary surgical CPT code to…

    Showing 1–10 of 13

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    363A00000X
    208D00000X
    207P00000X
    367A00000X
    332900000X
    207VC0200X
    207XX0005X
    246XS1301X

    Related Payer Policy Updates

    Specialty: General Surgery1 / 2

    10 rows

    PolicyPayerEffective Date
    Surgical ProceduresUnitedHealthcare2026-09-01
    Outpatient Surgical Procedures - Site of ServiceUnitedHealthcare2026-09-01
    Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Site of Service for Ambulatory Surgical Procedures (ASC Select)Premera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Outpatient Surgical Procedures - Site of Servicesierra health and life2026-08-01
    Medical Necessity Guidelines — Inpatient Surgical CareMass General Brigham Health Plan2026-08-01
    Ambulatory Surgery Center (ASC) - Site of Care PolicyKaiser Permanente2026-08-01

    Related Codes

    CPT-50010-RENAL-DIAGNOSTIC-EXPLORATION-KIDNEY

    CPT 50010: Diagnostic Exploration of Kidney

    CPT-50020-OPEN-DRAINAGE-RENAL-PERIRENAL-ABSCESS

    CPT 50020: Open Drainage of Renal or Perirenal Abscess

    CPT-50040-CREATION-OF-RENAL-CUTANEOUS-FISTULA-NEPHROSTOMY

    CPT 50040: Open Nephrostomy for Urinary Obstruction

    CPT-50045-URINARY-OBSTRUCTION-RELIEF-SURGICAL-PROCEDURE

    CPT 50045: Surgical Relief of Urinary Tract Obstruction

    CPT-50060-SURGICAL-REMOVAL-KIDNEY-STONE

    CPT 50060: Surgical Removal of Kidney Stones (Nephrolithiasis)

    CPT-50070-KIDNEY-INCISION-STONE-REMOVAL-CONGENITAL-MALFORMATION

    CPT 50070: Nephrolithotomy for Renal Calculi with Kidney Malformation

    CPT-50075-OPEN-NEPHROLITHOTOMY-STAGHORN-CALCULUS-REMOVAL

    CPT 50075: Nephrolithotomy for Staghorn Renal Calculus

    CPT-50080-PERCUTANEOUS-ANTEGRADE-RENAL-STONE-REMOVAL-SIMPLE

    CPT 50080: Percutaneous Nephrolithotomy, Antegrade Stone Removal (Simple)

    CPT-50081-PERCUTANEOUS-ANTEGRADE-RENAL-URETERAL-STONE-REMOVAL-COMPLEX

    CPT 50081: Percutaneous Antegrade Removal of Kidney/Ureteral Stones

    CPT-50100-UPJ-REPAIR-RENAL-VESSEL-REPOSITIONING

    CPT 50100: Reposition/Incision of Aberrant Renal Vessels for UPJ Obstruction

    Showing 1–10 of 13

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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