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    OpenPayerBilling CodesIncision Procedures on the KidneyCPT cpt-50075-open-nephrolithotomy-staghorn-calculus-removal
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    CPT 50075: Nephrolithotomy for Staghorn Renal Calculus

    Medicare pays $1318 on average nationally for this procedure.

    CPT code 50075 describes an open surgical nephrolithotomy for removal of a large staghorn renal calculus (struvite or branched kidney stone); the service is a surgical removal of a complex, branched stone via an incision in the kidney and is typically performed in an inpatient or operating room setting under general anesthesia as a urologic operative procedure.

    For related coverage guidance, see recent payer policy updates: Surgical Procedures, Outpatient Surgical Procedures - Site of Service, Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in Adults.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 52-year-old female presents with recurrent flank pain, gross hematuria, and recurrent urinary tract infections. Imaging with non-contrast CT demonstrates a large, branching staghorn calculus occupying the renal pelvis and calyces of the left kidney with associated hydronephrosis and evidence of infected urine. After urology evaluation and preoperative optimization, the patient is brought to the operating room for an open or minimally invasive surgical removal of the staghorn calculus via a direct incision into the renal pelvis or parenchyma. The procedure includes intraoperative stone removal, possible nephrotomy, hemostasis, placement of drains or ureteral stent as indicated, and specimen handling for stone analysis and culture.

    Typical workflow:

    • Preoperative evaluation: history, labs (CBC, BMP, coagulation), urine culture, imaging review, anesthesia assessment.

    • Informed consent documenting risks (bleeding, infection, renal injury), planned approach, and potential need for additional procedures.

    • Intraoperative: general anesthesia, incision to access kidney, nephrotomy or pyelotomy, extraction of branched stone fragments, irrigation, control of bleeding, possible placement of nephrostomy tube or ureteral stent, wound closure.

    • Postoperative: monitoring for bleeding and infection, pain control, antibiotics guided by culture, imaging follow-up, outpatient stone analysis and metabolic workup referral as indicated.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    50590Ureteral and/or renal stone removal, other than nephrolithotomy; which may include use of nephrostomy or ureteral catheterAlternative percutaneous approaches for stone removal when nephrolithotomy is performed percutaneously
    50080Renal pyelolithotomy or nephrotomy; with removal of calculus (other than staghorn)Closely related open renal stone procedures differing by indication or stone type
    52332Cystoureteroscopy, with lithotripsy (ureteral and/or renal); with ureteral catheterization, with/without stentEndoscopic approach used preoperatively or postoperatively for ureteral stones or stent placement
    50600Pyelolithotomy (open incision into renal pelvis)Procedure similar in approach when stone is localized to pelvis rather than large staghorn branching
    52000Cystourethroscopy, diagnosticCommon diagnostic/adjunctive procedure for evaluation of lower tract or stent placement

    Related Modifiers

    13 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    63Modifier‑63 is appended to surgical CPT codes (20000–69990) when a procedure is performed on a neonate or infant weighing ≤ 4 kg (about 8.8 lbs). The AMA/AAPC definition specifies this use and notes…- Use modifier -63 only for surgical procedures in the CPT 20000–69990 series performed on a neonate or infant who weighs ≤ 4 kg at the time of the procedure; it indicates increased complexity due to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…

    Showing 1–10 of 13

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    363A00000X
    207P00000X
    2082S0105X
    2085R0203X
    246X00000X
    283XC2000X
    225XM0800X
    207VG0400X

    Related ICD-10-CM Codes

    25 rows

    ICD-10-CM CodeDescription
    B96.0Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified elsewhere
    E87.1Hypo-osmolality and hyponatremia
    N10Acute pyelonephritis
    N11.0Nonobstructive reflux-associated chronic pyelonephritis
    N11.1Chronic obstructive pyelonephritis
    N13.2Hydronephrosis with renal and ureteral calculous obstruction
    N20.0Calculus of kidney
    N20.1Calculus of ureter
    N20.2Calculus of kidney with calculus of ureter
    N20.9Urinary calculus, unspecified

    Showing 1–10 of 25

    Related Payer Policy Updates

    Specialty: General Surgery1 / 2

    10 rows

    PolicyPayerEffective Date
    Surgical ProceduresUnitedHealthcare2026-09-01
    Outpatient Surgical Procedures - Site of ServiceUnitedHealthcare2026-09-01
    Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Site of Service for Ambulatory Surgical Procedures (ASC Select)Premera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Outpatient Surgical Procedures - Site of Servicesierra health and life2026-08-01
    Medical Necessity Guidelines — Inpatient Surgical CareMass General Brigham Health Plan2026-08-01
    Ambulatory Surgery Center (ASC) - Site of Care PolicyKaiser Permanente2026-08-01

    Related Codes

    CPT-50010-RENAL-DIAGNOSTIC-EXPLORATION-KIDNEY

    CPT 50010: Diagnostic Exploration of Kidney

    CPT-50020-OPEN-DRAINAGE-RENAL-PERIRENAL-ABSCESS

    CPT 50020: Open Drainage of Renal or Perirenal Abscess

    CPT-50040-CREATION-OF-RENAL-CUTANEOUS-FISTULA-NEPHROSTOMY

    CPT 50040: Open Nephrostomy for Urinary Obstruction

    CPT-50045-URINARY-OBSTRUCTION-RELIEF-SURGICAL-PROCEDURE

    CPT 50045: Surgical Relief of Urinary Tract Obstruction

    CPT-50060-SURGICAL-REMOVAL-KIDNEY-STONE

    CPT 50060: Surgical Removal of Kidney Stones (Nephrolithiasis)

    CPT-50065-NEPHROLITHOTOMY-SECONDARY-PROCEDURE-RENAL-STONE-REMOVAL

    CPT 50065: Nephrolithotomy for Kidney Stone Removal

    CPT-50070-KIDNEY-INCISION-STONE-REMOVAL-CONGENITAL-MALFORMATION

    CPT 50070: Nephrolithotomy for Renal Calculi with Kidney Malformation

    CPT-50080-PERCUTANEOUS-ANTEGRADE-RENAL-STONE-REMOVAL-SIMPLE

    CPT 50080: Percutaneous Nephrolithotomy, Antegrade Stone Removal (Simple)

    CPT-50081-PERCUTANEOUS-ANTEGRADE-RENAL-URETERAL-STONE-REMOVAL-COMPLEX

    CPT 50081: Percutaneous Antegrade Removal of Kidney/Ureteral Stones

    CPT-50100-UPJ-REPAIR-RENAL-VESSEL-REPOSITIONING

    CPT 50100: Reposition/Incision of Aberrant Renal Vessels for UPJ Obstruction

    Showing 1–10 of 13

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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