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    v1.0.30
    OpenPayerBilling CodesPancreas Transplantation ProceduresCPT cpt-48551-pancreas-donor-preparation-for-transplantation
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    CPT 48551: Pancreas Preparation from Deceased Donor for Transplant

    CPT code 48551 describes preparation of a pancreas from a deceased donor for transplantation, including removal of nonessential tissue and ligation of vessels performed in a sterile separate work area prior to transfer to the transplant recipient; service type: organ procurement/preparation; typical site of service: operating room or designated organ-procurement suite within a hospital setting.

    For related coverage guidance, see recent payer policy updates: Dental Anesthesia Services, Anesthesia Services for Interventional Pain Management Procedures in an Adult, General Anesthesia and Conscious Sedation Services.

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    Clinical & Coding Specifications

    Clinical Context

    A 28-year-old male donor is brought to the hospital operating suite after confirmation of brain death and authorization for organ donation. The transplant surgical team prepares the recovered pancreas in a sterile back-table area for subsequent transplantation into a matched recipient. The donor pancreas is inspected, excess peripancreatic fat and connective tissue are removed, small arterial and venous branches and the pancreatic duct are ligated or oversewn, and the organ is flushed and packaged for transport to the recipient operating room or transplant center. The procedure is performed in a separate work area of the operating room by a transplant surgeon or designated procurement surgeon. Typical workflow includes donor evaluation and consent, organ recovery team coordination, pancreas procurement and back-table preparation, documentation of organ condition and ischemia times, and transfer of the prepared organ to the recipient team for implantation. Typical site of service is the operating room within a hospital during an organ procurement procedure; staff may include transplant surgeons, anesthesiologists for donor care, scrub and circulating nurses, and organ procurement coordinators.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    48551Preparation of pancreas for transplantation, from cadaver donor; removal of unneeded tissue and ligation of vessels in a separate work areaPrimary code describing the back-table preparation procedure.

    | 47135 | Pancreatectomy, total or subtotal, for transplantation (donor) | May be performed earlier in the donor operation to remove the pancreas before back-table preparation coded with 48551.

    | 33945 | Donor heart procurement, with cold preservation and transport; without cardiopulmonary bypass | Represents other organ procurement procedures that commonly occur during multiorgan donor operations coordinated with pancreas preparation.

    | 49568 | Preparation of abdominal wall for organ procurement (not otherwise classified) | Reflects additional donor abdominal preparation services sometimes performed during multiorgan recovery.

    | 99100 | Anesthesia for patient of extreme age, younger than 1 year and older than 70 years (example anesthesia add-on) | An example of anesthesia considerations during donor management; anesthesia codes and modifiers vary by payer and are part of the peri-procurement workflow.

    | 31500 | Intubation, endotracheal, emergency procedure (separate procedure) | Airway management procedures may occur during donor management prior to or during organ procurement and preparation.

    Related Modifiers

    10 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    56Modifier ‑56 indicates the reporting provider furnished only the preoperative management for a surgical procedure and did not perform the intraoperative or postoperative care. It is used in…- Use Modifier -56 when a provider performs only the preoperative management in a split‑care situation (one physician manages preop care while a different physician performs the intraoperative…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…
    81Modifier -81 indicates a physician served as a minimal assistant surgeon for part—not all—of an operative procedure. Use when a physician’s assisting role is limited and does not represent full…- Use CPT modifier -81 when a physician acts as a minimum assistant surgeon who assists during only part (a limited portion) of an operative procedure; append -81 to the primary surgical CPT code to…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207P00000X
    2080P0202X
    2084P0800X
    363L00000X
    2083T0002X
    207LP4000X
    204R00000X
    170100000X

    Related Payer Policy Updates

    Specialty: Anesthesiology1 / 3

    10 rows

    PolicyPayerEffective Date
    Dental Anesthesia ServicesProvidence Health Plan2026-10-01
    Anesthesia Services for Interventional Pain Management Procedures in an AdultCigna2026-09-15
    General Anesthesia and Conscious Sedation ServicesUnitedHealthcare2026-09-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Elective Inpatient Services (for Idaho Only)UnitedHealthcare2026-06-01
    Sites of Servicepriority health2026-06-01
    Coverage for Ambulatory Surgery Unit (ASU)/Outpatient Facility and Anesthesia for Dental Servicesuniverahealthcare2026-05-21

    Related Codes

    CPT-48550-PANCREAS-PROCUREMENT-DONOR-ORGAN-RECOVERY

    CPT 48550: Pancreas Retrieval from Deceased Donor

    CPT-48552-DONOR-PANCREAS-VEIN-RECONSTRUCTION-ORGAN-PREPARATION

    CPT 48552: Pancreas Vein Reconstruction for Donor Organ Preparation

    CPT-48554-PANCREAS-ALLOGRAFT-IMPLANTATION-EXTRACORPOREAL-DONOR

    CPT 48554: Cadaveric Pancreas Implantation, Native Pancreas Retained

    CPT-48556-DONOR-PANCREAS-EXPLANTATION

    CPT 48556: Explantation of Transplanted Pancreas

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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