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    OpenPayerBilling CodesPancreas Transplantation ProceduresCPT cpt-48550-pancreas-procurement-donor-organ-recovery
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    CPT 48550: Pancreas Retrieval from Deceased Donor

    CPT code 48550 describes surgical retrieval of a pancreas from a cadaveric (deceased) organ donor, which may include removal of a duodenal segment, with preservation of the organ in cold storage for subsequent transplantation; service type: organ procurement surgery, typical site of service: hospital operating room or organ procurement facility.

    For related coverage guidance, see recent payer policy updates: Dental Anesthesia Services, Anesthesia Services for Interventional Pain Management Procedures in an Adult, General Anesthesia and Conscious Sedation Services.

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient scenario involves a deceased organ donor in a hospital intensive care unit who has been declared brain dead after catastrophic neurologic injury (for example, traumatic brain injury or intracranial hemorrhage). The organ procurement organization (OPO) coordinates with the donor hospital, transplant surgeons, and the recipient transplant center. After donor evaluation and consent for pancreas donation, a transplant surgery team travels to the donor site or operates within the donor hospital sterile operating room. The team performs a donor pancreatectomy, which may include a segment of the duodenum, and preserves the pancreas in a cold, sterile preservation solution for transport. Clinical workflow steps include donor medical and infectious screening, organ allocation, operating room preparation, organ removal (donor pancreatectomy), back-table preparation and preservation in cold storage, documentation of organ condition and ischemia times, and transport to the recipient center for transplantation.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    48550Removal of pancreas for transplant (donor pancreatectomy)Primary procedure: donor organ procurement and preservation for transplant
    48600Donor splenectomy, when performed during multiorgan procurementPerformed during multiorgan procurements when spleen removal is required for exposure or allocation
    49650Laparoscopic donor nephrectomy, completeFrequently performed during multiorgan procurement operations when kidney retrieval is also needed (different code for open nephrectomy)
    44320Resection, small intestine; single resection and anastomosis, for duodenal segment inclusionMay relate when a duodenal segment is removed with the pancreas and requires separate coding for bowel resection if reportable
    37799Unlisted procedure, vascular surgeryUsed for unusual vascular reconstruction or procurement-related vascular procedures not described by standard codes

    Related Modifiers

    13 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    56Modifier ‑56 indicates the reporting provider furnished only the preoperative management for a surgical procedure and did not perform the intraoperative or postoperative care. It is used in…- Use Modifier -56 when a provider performs only the preoperative management in a split‑care situation (one physician manages preop care while a different physician performs the intraoperative…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…
    73Modifier 73 indicates a facility-level outpatient hospital or ASC procedure that was discontinued after the patient was prepared and taken to the procedure/operating room but before any anesthesia…- When to use: Apply CPT modifier 73 on the FACILITY (outpatient hospital or ASC) claim when the patient has been fully prepared and physically taken into the procedure/operating room but the…

    Showing 1–10 of 13

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    208000000X
    207P00000X
    207L00000X
    2278H0200X
    261QA0900X
    163WC1400X
    207XS0106X
    237700000X

    Related ICD-10-CM Codes

    22 rows

    ICD-10-CM CodeDescription
    C25.4Malignant neoplasm of endocrine pancreas
    C25.9Malignant neoplasm of pancreas, unspecified
    D50.9Iron deficiency anemia, unspecified
    D63.8Anemia in other chronic diseases classified elsewhere
    E08.65Diabetes mellitus due to underlying condition with hyperglycemia
    E08.9Diabetes mellitus due to underlying condition without complications
    E10.65Type 1 diabetes mellitus with hyperglycemia
    E10.9Type 1 diabetes mellitus without complications
    E11.65Type 2 diabetes mellitus with hyperglycemia
    E11.9Type 2 diabetes mellitus without complications

    Showing 1–10 of 22

    Related Payer Policy Updates

    Specialty: Anesthesiology1 / 3

    10 rows

    PolicyPayerEffective Date
    Dental Anesthesia ServicesProvidence Health Plan2026-10-01
    Anesthesia Services for Interventional Pain Management Procedures in an AdultCigna2026-09-15
    General Anesthesia and Conscious Sedation ServicesUnitedHealthcare2026-09-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Elective Inpatient Services (for Idaho Only)UnitedHealthcare2026-06-01
    Sites of Servicepriority health2026-06-01
    Coverage for Ambulatory Surgery Unit (ASU)/Outpatient Facility and Anesthesia for Dental Servicesuniverahealthcare2026-05-21

    Related Codes

    CPT-48551-PANCREAS-DONOR-PREPARATION-FOR-TRANSPLANTATION

    CPT 48551: Pancreas Preparation from Deceased Donor for Transplant

    CPT-48552-DONOR-PANCREAS-VEIN-RECONSTRUCTION-ORGAN-PREPARATION

    CPT 48552: Pancreas Vein Reconstruction for Donor Organ Preparation

    CPT-48554-PANCREAS-ALLOGRAFT-IMPLANTATION-EXTRACORPOREAL-DONOR

    CPT 48554: Cadaveric Pancreas Implantation, Native Pancreas Retained

    CPT-48556-DONOR-PANCREAS-EXPLANTATION

    CPT 48556: Explantation of Transplanted Pancreas

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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