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    v1.0.30
    OpenPayerBilling CodesDestruction Procedures on the AnusCPT cpt-46922-anal-lesion-destruction-excision
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    CPT 46922: Anal Lesion Destruction by Excision

    Medicare pays $358 on average nationally for this procedure.

    CPT code 46922 describes surgical destruction by excision of an anal lesion (for example, condyloma, papilloma, molluscum contagiosum, or herpetic vesicle) and is billed as a minor surgical procedure; service type: surgical destruction/excision; typical site of service: outpatient surgery or procedure room in a clinic or ambulatory surgical center.

    For related coverage guidance, see recent payer policy updates: Percutaneous Electrical Nerve Field Stimulation for Functional Abdominal Pain Disorders, Esophagogastroduodenoscopy (EGD) Coverage Policy, Radiofrequency Therapy for Fecal Incontinence.

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    Clinical & Coding Specifications

    Clinical Context

    A 34-year-old patient presents to an outpatient colorectal clinic with a focal, symptomatic anal condyloma that has persisted despite topical therapy. The evaluation includes history, focused anorectal examination with anoscopy, and photographic documentation. Based on lesion size, location, and patient preference, the colorectal or general surgeon performs operative destruction by surgical excision under local anesthesia with monitored sedation or under general anesthesia if multiple lesions or patient tolerance requires it. The procedure room or ambulatory surgery center is the typical site of service. Routine steps include lesion marking, infiltration with local anesthetic, careful excision with electrocautery or scalpel, hemostasis, specimen handling if pathology indicated, and post-procedure wound care instructions. Peri-procedural documentation includes lesion size, method of destruction, anesthesia administered, specimen disposition, and any immediate complications. Coding uses 46922 for destruction by excision of an anal lesion when operative excision is performed.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    Data not available in the input.Data not available in the input.Data not available in the input.

    Related Modifiers

    8 rows

    ModifierDescriptionWhen to Use
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    2251C2600X
    163WN0003X
    2471B0102X
    2278P4000X
    251E00000X
    174MM1900X
    207R00000X
    207XX0801X

    Related ICD-10-CM Codes

    20 rows

    ICD-10-CM CodeDescription
    A60.9Anogenital herpesviral infection, unspecified
    A63.0Anogenital (venereal) warts
    B00.9Herpesviral infection, unspecified
    B07.8Other viral warts
    B07.9Viral wart, unspecified
    D01.2Carcinoma in situ of rectum
    D04.4Carcinoma in situ of skin of scalp and neck
    D23.5Other benign neoplasm of skin of trunk
    K62.5Hemorrhage of anus and rectum
    K62.6Ulcer of anus and rectum

    Showing 1–10 of 20

    Related Payer Policy Updates

    Specialty: Gastroenterology1 / 3

    10 rows

    PolicyPayerEffective Date
    Percutaneous Electrical Nerve Field Stimulation for Functional Abdominal Pain Disordersbcbsvermont2026-12-01
    Esophagogastroduodenoscopy (EGD) Coverage Policyevicore2026-11-05
    Radiofrequency Therapy for Fecal IncontinenceCigna2026-10-15
    Magnetic Sphincter Augmentation for the Treatment of Gastroesophageal Reflux Disease (GERD)univerahealthcare2026-10-15
    High-Resolution Anoscopy (HRA)Premera Bluecross2026-10-01
    Gastroesophageal and Gastrointestinal (GI) Services and ProceduresColorado Rocky Mountain Health Plans2026-10-01
    Fecal Analysis in the Diagnosis of Intestinal Dysbiosis and Fecal Microbiota Transplant TestingOscar Health2026-10-01
    Serum Testing for Hepatic Fibrosis in the Evaluation and Monitoring of Chronic Liver DiseaseOscar Health2026-10-01
    Pancreatic Enzyme Testing for Acute PancreatitisOscar Health2026-10-01
    Helicobacter pylori TestingOscar Health2026-10-01

    Related Codes

    CPT-46900-CHEMICAL-DESTRUCTION-ANAL-LESION

    CPT 46900: Chemical Destruction of Anal Lesion

    CPT-46910-ANAL-LESION-DESTRUCTION-CAUTERY

    CPT 46910: Destruction of Anal Lesion by Electrocautery

    CPT-46916-ANAL-LESION-DESTRUCTION-CRYOTHERAPY

    CPT 46916: Destruction of Anal Lesion by Cryotherapy

    CPT-46917-ANAL-LESION-DESTRUCTION-LASER

    CPT 46917: Laser Destruction of Anal Lesion

    CPT-46924-EXTENSIVE-ANAL-LESION-DESTRUCTION

    CPT 46924: Extensive Destruction of Anal Lesion

    CPT-46930-INTERNAL-HEMORRHOID-THERMAL-DESTRUCTION

    CPT 46930: Destruction of Internal Hemorrhoids by Thermal Techniques

    CPT-46940-ANAL-FISSURE-OTOMY-AND-SPHINCTER-DILATION

    CPT 46940: Anal Fissure Excision with Anal Sphincter Dilation

    CPT-46942-ANAL-FISSURE-DEBRIDEMENT-AND-SPHINCTER-DILATION-SUBSEQUENT

    CPT 46942: Anal Fissure Excision/Scraping with Sphincter Dilation, Subsequent

    CPT-46945-HEMORRHOIDECTOMY-SINGLE-HEMORRHOID-EXCISION-NON-RUBBER-BAND

    CPT 46945: Hemorrhoidectomy, Single Hemorrhoid (Non-Band Technique)

    CPT-46946-EXCISION-MULTIPLE-HEMORRHOIDS-NON-RUBBER-BAND-TECHNIQUES

    CPT 46946: Hemorrhoidectomy, Two or More (Non-Rubber Band)

    Showing 1–10 of 12

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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