CPT code 46607 captures an anoscopy performed with high-resolution magnification and chemical agent enhancement, with biopsy of affected anal tissue. This code represents a diagnostic endoscopic procedure used to improve lesion detection in the anal canal and to obtain tissue for histologic assessment. Nationally, accurate coding for this procedure influences clinical documentation, pathology follow-up, and appropriate payment for specialized diagnostic techniques.

Key payers considered in this analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find an overview of clinical context, typical sites of service (outpatient clinic, ambulatory surgery center, hospital outpatient department), and common billing practices tied to this procedure. The publication outlines benchmarks for utilization and reimbursement where available, notes policy or coverage considerations that affect billing, and highlights coding nuances relevant to documentation and claims submission.

This summary is intended for billing professionals, clinicians who perform anoscopy with biopsy, and policy analysts seeking a concise reference on CPT code 46607 and its place in outpatient diagnostic services.