CPT code 45307 denotes a physician-performed lower gastrointestinal proctosigmoidoscopy, an endoscopic examination of the rectum and sigmoid colon. This procedure is commonly used for diagnostic evaluation of lower GI symptoms, targeted biopsies, and limited therapeutic maneuvers. Nationally, proctosigmoidoscopy is a frequently used lower GI diagnostic tool that influences colorectal disease detection, follow-up care, and procedural coding and billing practices across outpatient and ambulatory surgical settings.

Key payers covered in this analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. The publication outlines coverage patterns and coding considerations relevant to these payers and highlights common clinical contexts in which CPT code 45307 is used.

Readers will find a concise clinical and billing primer on the procedure, typical sites of service, and the scope of services represented by the code. The report also summarizes available benchmarks and policy considerations that affect utilization and reimbursement, and provides context for clinicians, billing professionals, and policy analysts seeking a national perspective on coding, claims handling, and administrative practices for proctosigmoidoscopy. Data not available in the input is noted where applicable.