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    v1.0.30
    OpenPayerBilling CodesExcision Procedures on the Intestines (Except Rectum)CPT cpt-44121-additional-small-intestine-resection-anastomosis
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    CPT 44121: Additional Small Intestine Resection and Anastomosis

    CPT code 44121 describes resection of one or more additional affected segments of the small intestine performed during the same operative session as the initial small intestine resection with anastomosis; service type: additional small bowel resection with primary anastomosis; typical site of service: inpatient or ambulatory surgical center during the index abdominal operation.

    For related coverage guidance, see recent payer policy updates: Percutaneous Electrical Nerve Field Stimulation for Functional Abdominal Pain Disorders, Esophagogastroduodenoscopy (EGD) Coverage Policy, Radiofrequency Therapy for Fecal Incontinence.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 62-year-old male with a history of Crohn disease presents with progressive abdominal pain, low-grade fever, and obstructive symptoms. Imaging (CT abdomen/pelvis) demonstrates two noncontiguous strictured segments of mid and distal ileum with proximal dilation and focal inflammatory change. After resuscitation and appropriate preoperative evaluation, the patient is taken to the operating room for an exploratory laparotomy. The surgeon performs an initial small intestine resection and primary anastomosis for the most diseased segment. During the same operative session the surgeon identifies an additional affected segment of small intestine that is ischemic and nonviable; the surgeon resects this additional segment and creates a single primary anastomosis connecting the remaining intestinal ends. Intraoperative findings, procedure notes, and pathology specimens document the two separate resections performed at the same session.

    Typical workflow steps:

    • Preoperative evaluation, informed consent, and documentation of indications (e.g., obstructive Crohn disease, ischemia, tumor).

    • Intraoperative exploration and determination of segments requiring resection.

    • Performance of the initial small intestine resection with anastomosis.

    • Performance of one or more additional small intestine resections during the same session followed by reconstruction/anastomosis of the remaining bowel.

    • Operative report clearly describing number of resections, locations, lengths of bowel removed, type of anastomosis, and any complications.

    • Post-anesthesia and postoperative documentation, pathology correlation, and coding to reflect the additional resections performed at the same session using 44121 when applicable.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    44120Resection of small intestine; single resection and anastomosisOften coded for the initial single small intestine resection and anastomosis; 44121 is used when one or more additional segments are resected at the same session.
    44202Laparoscopy, surgical; colectomy, partial, with anastomosisMay be performed in the same operative episode if colonic disease is addressed laparoscopically in conjunction with small bowel resections.
    44204Laparoscopy, surgical; colectomy, partial, with anastomosis, for diverticulitis or other diseaseRelated when combined colonic and small bowel disease are managed in same operative setting.
    44125Enterectomy, resection of small intestine with end-to-end anastomosis, multiple resectionsUsed when coding multiple discrete small intestine resections in some coding conventions; verify payer guidance relative to .

    Related Modifiers

    13 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    63Modifier‑63 is appended to surgical CPT codes (20000–69990) when a procedure is performed on a neonate or infant weighing ≤ 4 kg (about 8.8 lbs). The AMA/AAPC definition specifies this use and notes…- Use modifier -63 only for surgical procedures in the CPT 20000–69990 series performed on a neonate or infant who weighs ≤ 4 kg at the time of the procedure; it indicates increased complexity due to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…

    Showing 1–10 of 13

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207L00000X
    207LP2900X
    2279P3800X
    282J00000X
    2470A2800X
    2085R0001X
    163WP0218X
    207ZP0105X

    Related ICD-10-CM Codes

    23 rows

    ICD-10-CM CodeDescription
    A09Infectious gastroenteritis and colitis, unspecified
    K25.9Gastric ulcer, unspecified as acute or chronic, without hemorrhage or perforation
    K31.9Disease of stomach and duodenum, unspecified
    K35.80Unspecified acute appendicitis
    K55.9Vascular disorder of intestine, unspecified
    K57.00Diverticulitis of small intestine with perforation and abscess without bleeding
    K57.10Diverticulosis of small intestine without perforation or abscess without bleeding
    K57.12Diverticulitis of small intestine without perforation or abscess without bleeding
    K57.20Diverticulitis of large intestine with perforation and abscess without bleeding
    K57.21Diverticulitis of large intestine with perforation and abscess with bleeding

    Showing 1–10 of 23

    Related Payer Policy Updates

    Specialty: Gastroenterology1 / 4

    10 rows

    PolicyPayerEffective Date
    Percutaneous Electrical Nerve Field Stimulation for Functional Abdominal Pain Disordersbcbsvermont2026-12-01
    Esophagogastroduodenoscopy (EGD) Coverage Policyevicore2026-11-05
    Radiofrequency Therapy for Fecal IncontinenceCigna2026-10-15
    Magnetic Sphincter Augmentation for the Treatment of Gastroesophageal Reflux Disease (GERD)univerahealthcare2026-10-15
    High-Resolution Anoscopy (HRA)Premera Bluecross2026-10-01
    Gastroesophageal and Gastrointestinal (GI) Services and ProceduresColorado Rocky Mountain Health Plans2026-10-01
    Fecal Analysis in the Diagnosis of Intestinal Dysbiosis and Fecal Microbiota Transplant TestingOscar Health2026-10-01
    Serum Testing for Hepatic Fibrosis in the Evaluation and Monitoring of Chronic Liver DiseaseOscar Health2026-10-01
    Pancreatic Enzyme Testing for Acute PancreatitisOscar Health2026-10-01
    Helicobacter pylori TestingOscar Health2026-10-01

    Related Codes

    CPT-44100-SMALL-INTESTINE-CAPSULE-BIOPSY

    CPT 44100: Small Intestine Biopsy via Oral Capsule

    CPT-44110-OPEN-EXCISION-INTESTINAL-LESION-SINGLE-INCISION

    CPT 44110: Excision of Lesion(s) From Small or Large Intestine

    CPT-44111-INTESTINAL-LESION-EXCISION-MULTIPLE-INCISIONS

    CPT 44111: Excision of Intestinal Lesions via Multiple Incisions

    CPT-44120-SMALL-INTESTINE-RESECTION-PRIMARY-ANASTOMOSIS

    CPT 44120: Small Bowel Resection with Primary Anastomosis

    CPT-44125-SMALL-INTESTINE-RESECTION-WITH-STOMA-CREATION

    CPT 44125: Small Bowel Resection with Enterostomy

    CPT-44126-SMALL-BOWEL-RESECTION-CONGENITAL-ATRESIA-END-TO-END-ANASTOMOSIS

    CPT 44126: Small Bowel Resection for Intestinal Atresia with Anastomosis

    CPT-44127-SMALL-BOWEL-RESECTION-ANASTOMOSIS-INTESTINAL-ATRESIA

    CPT 44127: Resection and Anastomosis for Congenital Small-Bowel Atresia

    CPT-44128-SMALL-BOWEL-RESECTION-ANASTOMOSIS-CONGENITAL-ATRESIA

    CPT 44128: Resection of Small Intestine for Congenital Atresia

    CPT-44130-INTESTINAL-ANASTOMOSIS-BOWEL-RESECTION-ANASTOMOSIS

    CPT 44130: Intestinal Anastomosis, With or Without Stoma

    CPT-44132-DONOR-SMALL-BOWEL-RESECTION-PRESERVATION-FOR-TRANSPLANT

    CPT 44132: Open Small Intestine Resection for Transplant Preservation

    Showing 1–10 of 29

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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    44121
    49560Incision and drainage, incarcerated or strangulated hernia, with resection of small intestinePerformed when bowel resection is required emergently for strangulated hernia in the same operative episode.