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    v1.0.30
    OpenPayerBilling CodesLaparoscopic Procedures on the EsophagusCPT cpt-43289-unlisted-esophageal-procedure
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    CPT 43289: Unlisted Procedure, Esophagus

    CPT code 43289 is used to report an esophageal procedure that does not have a more specific CPT code; it represents an unlisted or unspecified procedure of the esophagus, typically performed as a diagnostic or therapeutic endoscopic/surgical service in settings such as an endoscopy suite, ambulatory surgery center, or hospital operating room.

    For related coverage guidance, see recent payer policy updates: Dental Anesthesia Services, Anesthesia Services for Interventional Pain Management Procedures in an Adult, General Anesthesia and Conscious Sedation Services.

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    Table of contents

    Progress1 / 7

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    Clinical & Coding Specifications

    Clinical Context

    A 62-year-old male with progressive dysphagia and unintentional weight loss is referred to gastroenterology. Diagnostic endoscopy identifies an esophageal lesion not amenable to removal with standard, specifically coded techniques; the endoscopist performs a non-routine esophageal procedure (for example, an unusual endoscopic mucosal resection variant, complex foreign-body extraction using atypical tools, or a novel repair of an iatrogenic esophageal perforation) that is not described by a specific CPT code. The patient is treated in an ambulatory endoscopy suite or inpatient operating room depending on comorbidities and complexity. The workflow includes pre-procedure consent and evaluation, endoscopic anesthesia (moderate sedation or general anesthesia with anesthesia professional documentation), performance of the unlisted esophageal procedure, intra-procedural documentation of technique and findings, and post-procedure recovery with discharge instructions or admission if needed. Operative report details the indication, steps, equipment, duration, complications, and estimated blood loss to support use of 43289 and any applicable modifiers and to enable payer review for medical necessity and reimbursement.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    43239Esophagoscopy, rigid or flexible, with removal of foreign bodyMay be performed before or instead of 43289 for standard foreign-body removals; used when a specific code applies.
    43247Upper gastrointestinal endoscopy including esophagus, stomach and either diagnostic or therapeutic interventions (EGD)Commonly performed for diagnostic evaluation prior to using an unlisted esophageal procedure code when complex therapy is needed.
    43254Esophagogastroduodenoscopy, diagnostic, with directed submucosal injection(s) and/or mucosal markingPerformed as part of staging or marking lesions when planning complex unlisted esophageal procedures.
    43282Esophagoscopy, flexible, with endoscopic mucosal resection when performed; single lesionMay be used when a standard EMR code applies; if the technique differs substantially, 43289 may be used instead.
    43287Esophagoscopy, flexible, with ablation of tumor; e.g., photodynamic therapy, laserAblative therapies for esophageal lesions that have specific codes; if an atypical ablation is performed without a specific code, 43289 might be reported.
    51701Insertion of temporary indwelling urethral catheterData not available in the input.

    Related Modifiers

    12 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    58Modifier 58 (Staged or related procedure/service by the same physician during the postoperative period) indicates that a subsequent procedure performed by the same provider during the…- Use modifier 58 when the same physician/QHP performs a procedure during the postoperative/global period of an earlier procedure and the subsequent procedure is either planned or anticipated…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…

    Showing 1–10 of 12

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207RG0300X
    2084P0800X
    363LS0200X
    2083P0011X
    2080P0205X
    332H00000X
    261QR0405X
    125J00000X

    Related ICD-10-CM Codes

    24 rows

    ICD-10-CM CodeDescription
    C15.3Malignant neoplasm of upper third of esophagus
    C15.4Malignant neoplasm of middle third of esophagus
    C15.9Malignant neoplasm of esophagus, unspecified
    I95.1Orthostatic hypotension
    K20.0Eosinophilic esophagitis
    K21.9Gastro-esophageal reflux disease without esophagitis
    K22.0Achalasia of cardia
    K22.2Esophageal obstruction
    K22.4Dyskinesia of esophagus
    K25.9Gastric ulcer, unspecified as acute or chronic, without hemorrhage or perforation

    Showing 1–10 of 24

    Related Payer Policy Updates

    Specialty: Anesthesiology1 / 3

    10 rows

    PolicyPayerEffective Date
    Dental Anesthesia ServicesProvidence Health Plan2026-10-01
    Anesthesia Services for Interventional Pain Management Procedures in an AdultCigna2026-09-15
    General Anesthesia and Conscious Sedation ServicesUnitedHealthcare2026-09-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Elective Inpatient Services (for Idaho Only)UnitedHealthcare2026-06-01
    Sites of Servicepriority health2026-06-01
    Coverage for Ambulatory Surgery Unit (ASU)/Outpatient Facility and Anesthesia for Dental Servicesuniverahealthcare2026-05-21

    Related Codes

    CPT-43279-LAPAROSCOPIC-ESOPHAGOMYOTOMY-WITH-OR-WITHOUT-FUNDOPLASTY

    CPT 43279: Laparoscopic Esophagomyotomy With or Without Fundoplasty

    CPT-43280-LAPAROSCOPIC-ESOPHAGOGASTRIC-FUNDOPLASTY-ANTIREFLUX-SURGERY

    CPT 43280: Laparoscopic Esophagogastric Fundoplasty

    CPT-43281-LAPAROSCOPIC-PARAESOPHAGEAL-HERNIA-REPAIR-FUNDOPLICATION

    CPT 43281: Laparoscopic Repair of Paraesophageal Hernia

    CPT-43282-LAPAROSCOPIC-PARAESOPHAGEAL-HERNIA-REPAIR-WITH-MESH

    CPT 43282: Laparoscopic Paraesophageal Hernia Repair with Fundoplication

    CPT-43283-LAPAROSCOPIC-ESOPHAGEAL-LENGTHENING-WITH-FUNDOPLASTY

    CPT 43283: Laparoscopic Esophageal Lengthening with Fundoplasty/Hernia Repair

    CPT-43284-LAPAROSCOPIC-MAGNETIC-SPHINCTER-AUGMENTATION-ANTI-REFLUX

    CPT 43284: Laparoscopic Magnetic Sphincter Augmentation for GERD

    CPT-43285-REMOVAL-MAGNETIC-BAND-ESOPHAGOGASTRIC-JUNCTION

    CPT 43285: Removal of Magnetic Anti-Reflux Band at Esophagogastric Junction

    CPT-43286-ESOPHAGECTOMY-LAPAROSCOPIC-WITH-CERVICAL-RECONSTRUCTION

    CPT 43286: Esophagectomy with Pharyngogastrostomy or Esophagogastrostomy

    CPT-43287-LAPAROSCOPIC-THORACOSCOPIC-ESOPHAGECTOMY-ESOPHAGOGASTROSTOMY

    CPT 43287: Laparoscopic-Thoracoscopic Subtotal Esophagectomy with Esophagogastrostomy

    CPT-43288-THORACOSCOPIC-LAPAROSCOPIC-ESOPHAGECTOMY-CERVICAL-ANASTOMOSIS

    CPT 43288: Thoracoscopic/Laparoscopic Esophagectomy with Cervical Reconstruction

    Showing 1–10 of 11

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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