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    v1.0.30
    OpenPayerBilling CodesLaparoscopic Procedures on the EsophagusCPT cpt-43288-thoracoscopic-laparoscopic-esophagectomy-cervical-anastomosis
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    CPT 43288: Thoracoscopic/Laparoscopic Esophagectomy with Cervical Reconstruction

    Medicare pays $3479 on average nationally for this procedure.

    CPT code 43288 describes a combined thoracoscopic, laparoscopic, and open cervical procedure in which the surgeon performs a near-total or total esophagectomy with mobilization of the mediastinal esophagus, resects the upper stomach as needed, and creates a pharyngogastrostomy or esophagogastrostomy via an open cervical approach; service type: major surgical resection with reconstruction (esophagectomy with gastric conduit/repair) performed using thoracoscopic and laparoscopic access plus open cervical anastomosis; typical site of service: inpatient operating room with postoperative inpatient recovery and intensive or surgical ward care.

    For related coverage guidance, see recent payer policy updates: Dental Anesthesia Services, Anesthesia Services for Interventional Pain Management Procedures in an Adult, General Anesthesia and Conscious Sedation Services.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 62-year-old male with biopsy-proven distal esophageal adenocarcinoma involving the mid and proximal esophagus presents after staging that demonstrates localized disease without distant metastases. He has progressive dysphagia, weight loss, and reflux symptoms refractory to endoscopic therapies. After multidisciplinary tumor board review, the surgical plan is a transthoracic thoracoscopic esophagectomy with removal of the majority of the esophagus, partial gastrectomy to create a gastric conduit, possible pyloric drainage, and a cervical anastomosis (pharyngogastrostomy or esophagogastrostomy) via an open neck incision.

    Preoperative workflow includes optimization of nutrition, pulmonary evaluation, informed consent outlining thoracoscopic, laparoscopic, and open cervical components, and coordination with anesthesia for single-lung ventilation. Intraoperative steps typically include thoracoscopic mobilization of the upper, middle, and lower mediastinal esophagus; laparoscopic gastric mobilization with possible pyloric drainage; creation of a conduit; and an open cervical approach for the anastomosis. Postoperative care includes ICU or step-down monitoring, pain control, early ambulation, swallow study prior to oral intake, and discharge planning with enteral nutrition support as needed.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    43288Removal of all or most of the esophagus via thoracoscopic techniques with partial gastrectomy and open cervical anastomosis (pharyngogastrostomy or esophagogastrostomy).Primary procedure described; includes thoracoscopic esophageal mobilization, laparoscopic gastric mobilization, and open cervical reconstruction.
    43289Removal of all or most of the esophagus using thoracoscopic techniques with thoracoabdominal or cervical anastomosis (alternative approach).Closely related variant when anastomosis location or technique differs; may be reported when clinical circumstances align with that specific descriptor.
    43287Thoracoscopic mobilization of esophagus, with limited resection or bypass procedures.May be used for less extensive thoracoscopic esophageal procedures that do not include the full resection and reconstruction described in 43288.
    43246Laparoscopy, surgical; esophagogastric fundoplasty (e.g., Nissen)Not typically part of esophagectomy but may be billed when separate anti-reflux procedures are performed in different contexts; included here as a related upper GI laparoscopic code.
    49560Repair of recurrent ventral hernia (example adjunct abdominal procedure)Represents ancillary abdominal procedures that could be performed concurrently; use depends on intra-abdominal findings and payer rules.

    Related Modifiers

    13 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    63Modifier‑63 is appended to surgical CPT codes (20000–69990) when a procedure is performed on a neonate or infant weighing ≤ 4 kg (about 8.8 lbs). The AMA/AAPC definition specifies this use and notes…- Use modifier -63 only for surgical procedures in the CPT 20000–69990 series performed on a neonate or infant who weighs ≤ 4 kg at the time of the procedure; it indicates increased complexity due to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…

    Showing 1–10 of 13

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    2084P0800X
    207K00000X
    363L00000X
    1223P0221X
    222Q00000X
    163WC1500X
    207QB0505X
    367A00000X

    Related ICD-10-CM Codes

    22 rows

    ICD-10-CM CodeDescription
    C15.3Malignant neoplasm of upper third of esophagus
    C15.4Malignant neoplasm of middle third of esophagus
    C15.5Malignant neoplasm of lower third of esophagus
    C15.8Malignant neoplasm of overlapping sites of esophagus
    C15.9Malignant neoplasm of esophagus, unspecified
    C16.1Malignant neoplasm of fundus of stomach
    C16.2Malignant neoplasm of body of stomach
    C16.9Malignant neoplasm of stomach, unspecified
    I85.01Esophageal varices with bleeding
    I85.11Secondary esophageal varices with bleeding

    Showing 1–10 of 22

    Related Payer Policy Updates

    Specialty: Anesthesiology1 / 3

    10 rows

    PolicyPayerEffective Date
    Dental Anesthesia ServicesProvidence Health Plan2026-10-01
    Anesthesia Services for Interventional Pain Management Procedures in an AdultCigna2026-09-15
    General Anesthesia and Conscious Sedation ServicesUnitedHealthcare2026-09-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Elective Inpatient Services (for Idaho Only)UnitedHealthcare2026-06-01
    Sites of Servicepriority health2026-06-01
    Coverage for Ambulatory Surgery Unit (ASU)/Outpatient Facility and Anesthesia for Dental Servicesuniverahealthcare2026-05-21

    Related Codes

    CPT-43279-LAPAROSCOPIC-ESOPHAGOMYOTOMY-WITH-OR-WITHOUT-FUNDOPLASTY

    CPT 43279: Laparoscopic Esophagomyotomy With or Without Fundoplasty

    CPT-43280-LAPAROSCOPIC-ESOPHAGOGASTRIC-FUNDOPLASTY-ANTIREFLUX-SURGERY

    CPT 43280: Laparoscopic Esophagogastric Fundoplasty

    CPT-43281-LAPAROSCOPIC-PARAESOPHAGEAL-HERNIA-REPAIR-FUNDOPLICATION

    CPT 43281: Laparoscopic Repair of Paraesophageal Hernia

    CPT-43282-LAPAROSCOPIC-PARAESOPHAGEAL-HERNIA-REPAIR-WITH-MESH

    CPT 43282: Laparoscopic Paraesophageal Hernia Repair with Fundoplication

    CPT-43283-LAPAROSCOPIC-ESOPHAGEAL-LENGTHENING-WITH-FUNDOPLASTY

    CPT 43283: Laparoscopic Esophageal Lengthening with Fundoplasty/Hernia Repair

    CPT-43284-LAPAROSCOPIC-MAGNETIC-SPHINCTER-AUGMENTATION-ANTI-REFLUX

    CPT 43284: Laparoscopic Magnetic Sphincter Augmentation for GERD

    CPT-43285-REMOVAL-MAGNETIC-BAND-ESOPHAGOGASTRIC-JUNCTION

    CPT 43285: Removal of Magnetic Anti-Reflux Band at Esophagogastric Junction

    CPT-43286-ESOPHAGECTOMY-LAPAROSCOPIC-WITH-CERVICAL-RECONSTRUCTION

    CPT 43286: Esophagectomy with Pharyngogastrostomy or Esophagogastrostomy

    CPT-43287-LAPAROSCOPIC-THORACOSCOPIC-ESOPHAGECTOMY-ESOPHAGOGASTROSTOMY

    CPT 43287: Laparoscopic-Thoracoscopic Subtotal Esophagectomy with Esophagogastrostomy

    CPT-43289-UNLISTED-ESOPHAGEAL-PROCEDURE

    CPT 43289: Unlisted Procedure, Esophagus

    Showing 1–10 of 11

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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