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    OpenPayerBilling CodesLaparoscopic Procedures on the EsophagusCPT cpt-43280-laparoscopic-esophagogastric-fundoplasty-antireflux-surgery
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    CPT 43280: Laparoscopic Esophagogastric Fundoplasty

    Medicare pays $1019 on average nationally for this procedure.

    CPT code 43280 describes a laparoscopic esophagogastric fundoplasty (Nissen fundoplication) in which the surgeon wraps the upper stomach around the lower esophagus to reduce gastroesophageal reflux; service type: laparoscopic anti-reflux surgical procedure; typical site of service: inpatient or outpatient hospital operating room or ambulatory surgery center for minimally invasive foregut surgery.

    For related coverage guidance, see recent payer policy updates: Dental Anesthesia Services, Anesthesia Services for Interventional Pain Management Procedures in an Adult, General Anesthesia and Conscious Sedation Services.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 48-year-old patient with long-standing symptomatic gastroesophageal reflux disease (GERD) refractory to optimized medical therapy presents for surgical management. The surgeon performs a 43280 laparoscopic esophagogastric fundoplasty (Nissen or partial fundoplication) to reinforce the lower esophageal sphincter by wrapping the gastric fundus around the distal esophagus. Preoperative evaluation includes upper endoscopy, esophageal manometry, and 24-hour pH monitoring to confirm reflux etiology and rule out motility disorders. The procedure is performed in an ambulatory surgery center or hospital operating room under general anesthesia with laparoscopic access. Intraoperative steps include hiatal dissection, crural repair if a hiatal hernia is present, mobilization of the gastric fundus, creation of the fundoplication wrap, and confirmation of wrap tension and position. Postoperative workflow includes recovery room monitoring, early ambulation, diet advancement from clear liquids to soft diet, discharge instructions for activity restrictions, and outpatient follow-up with the surgeon for wound and symptom assessment. Typical indications include chronic reflux symptoms, regurgitation, or complications of GERD such as erosive esophagitis or Barrett esophagus where surgical intervention is appropriate.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    43280Laparoscopic esophagogastric fundoplasty (e.g., Nissen)Primary procedural code for laparoscopic fundoplication to treat GERD.
    43281Laparoscopic revision of fundoplicationUsed when revision or takedown of a prior 43280 is required due to failure or complications.
    43289Laparoscopy, surgical; other procedure (specify)Sometimes used for additional laparoscopic foregut procedures performed concurrently with 43280 when no specific code applies.
    43200Esophagoscopy, flexible, diagnostic, with or without collection of specimen by brushing or washing; with/without biopsyPerformed preoperatively or intraoperatively for diagnostic evaluation of esophageal mucosa related to indications for 43280.
    43644Laparoscopy, surgical, gastric restrictive procedure; with gastric bypass and Roux-en-Y gastroenterostomy (roux limb 150 cm or less)Different bariatric procedure — listed here when concurrent bariatric operations or conversions are part of the surgical plan; not typically performed with 43280 but relevant in foregut surgical workflows.
    43255Laparoscopy, surgical; esophagogastric fundoplasty (e.g., Nissen) — alternative codingHistorically used as an alternate approach; verify payer guidance for preferred coding when performing fundoplication.

    Related Modifiers

    13 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…
    73Modifier 73 indicates a facility-level outpatient hospital or ASC procedure that was discontinued after the patient was prepared and taken to the procedure/operating room but before any anesthesia…- When to use: Apply CPT modifier 73 on the FACILITY (outpatient hospital or ASC) claim when the patient has been fully prepared and physically taken into the procedure/operating room but the…
    74Modifier ‑74 indicates an outpatient hospital or ASC procedure that was discontinued after anesthesia was administered and after the procedure had begun. Use this modifier when anesthesia (local,…- Use modifier -74 when a procedure in an outpatient hospital or ASC setting is terminated after anesthesia has been administered and after the procedure has commenced (for example, after incision,…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…

    Showing 1–10 of 13

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    208000000X
    208600000X
    207L00000X
    363L00000X
    208100000X
    374J00000X
    207XX0801X
    3336I0012X

    Related Payer Policy Updates

    Specialty: Anesthesiology1 / 3

    10 rows

    PolicyPayerEffective Date
    Dental Anesthesia ServicesProvidence Health Plan2026-10-01
    Anesthesia Services for Interventional Pain Management Procedures in an AdultCigna2026-09-15
    General Anesthesia and Conscious Sedation ServicesUnitedHealthcare2026-09-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Elective Inpatient Services (for Idaho Only)UnitedHealthcare2026-06-01
    Sites of Servicepriority health2026-06-01
    Coverage for Ambulatory Surgery Unit (ASU)/Outpatient Facility and Anesthesia for Dental Servicesuniverahealthcare2026-05-21

    Related Codes

    CPT-43279-LAPAROSCOPIC-ESOPHAGOMYOTOMY-WITH-OR-WITHOUT-FUNDOPLASTY

    CPT 43279: Laparoscopic Esophagomyotomy With or Without Fundoplasty

    CPT-43281-LAPAROSCOPIC-PARAESOPHAGEAL-HERNIA-REPAIR-FUNDOPLICATION

    CPT 43281: Laparoscopic Repair of Paraesophageal Hernia

    CPT-43282-LAPAROSCOPIC-PARAESOPHAGEAL-HERNIA-REPAIR-WITH-MESH

    CPT 43282: Laparoscopic Paraesophageal Hernia Repair with Fundoplication

    CPT-43283-LAPAROSCOPIC-ESOPHAGEAL-LENGTHENING-WITH-FUNDOPLASTY

    CPT 43283: Laparoscopic Esophageal Lengthening with Fundoplasty/Hernia Repair

    CPT-43284-LAPAROSCOPIC-MAGNETIC-SPHINCTER-AUGMENTATION-ANTI-REFLUX

    CPT 43284: Laparoscopic Magnetic Sphincter Augmentation for GERD

    CPT-43285-REMOVAL-MAGNETIC-BAND-ESOPHAGOGASTRIC-JUNCTION

    CPT 43285: Removal of Magnetic Anti-Reflux Band at Esophagogastric Junction

    CPT-43286-ESOPHAGECTOMY-LAPAROSCOPIC-WITH-CERVICAL-RECONSTRUCTION

    CPT 43286: Esophagectomy with Pharyngogastrostomy or Esophagogastrostomy

    CPT-43287-LAPAROSCOPIC-THORACOSCOPIC-ESOPHAGECTOMY-ESOPHAGOGASTROSTOMY

    CPT 43287: Laparoscopic-Thoracoscopic Subtotal Esophagectomy with Esophagogastrostomy

    CPT-43288-THORACOSCOPIC-LAPAROSCOPIC-ESOPHAGECTOMY-CERVICAL-ANASTOMOSIS

    CPT 43288: Thoracoscopic/Laparoscopic Esophagectomy with Cervical Reconstruction

    CPT-43289-UNLISTED-ESOPHAGEAL-PROCEDURE

    CPT 43289: Unlisted Procedure, Esophagus

    Showing 1–10 of 11

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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