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    OpenPayerBilling CodesExcision Procedures on the Femur (Thigh Region) and Knee JointCPT cpt-27326-popliteal-gastrocnemius-nerve-excision-for-spasm
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    CPT 27326: Neurectomy of Popliteal/Gastrocnemius Nerve for Spasm

    Medicare pays $516 on average nationally for this procedure.

    CPT code 27326 describes surgical excision of part of or an entire nerve in the popliteal or gastrocnemius region performed to relieve muscle spasms; this is a neurectomy/denervation procedure typically performed as a surgical/operative service in an ambulatory surgery center or inpatient hospital operating room for patients with refractory spasticity affecting the posterior knee/calf musculature.

    For related coverage guidance, see recent payer policy updates: Removal of Implantable, Outpatient Surgical Procedures - Site of Service, Surgical Procedures.

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    Clinical & Coding Specifications

    Clinical Context

    A 45-year-old patient with chronic, focal gastrocnemius muscle spasm refractory to conservative measures presents for surgical management. The patient reports persistent calf pain and involuntary muscle contractions worsening daily despite physical therapy, oral muscle relaxants, and botulinum toxin injections. Preoperative evaluation by the orthopedic surgeon and anesthesiologist includes focused lower-extremity neurovascular exam, review of prior electromyography (EMG) and nerve conduction studies demonstrating focal motor nerve hyperactivity, and imaging to rule out compressive pathology. In the operating room under regional or general anesthesia, the surgeon performs a partial excision or resection of a branch of the tibial nerve supplying the gastrocnemius/popliteal region to relieve spasm. Postoperative workflow includes immediate neurovascular checks, pain control, physical therapy planning, and documentation of laterality and any intraoperative events for coding and billing. Typical site of service is an ambulatory surgery center or hospital outpatient department. Service type is surgical – peripheral nerve procedure of the popliteal/gastrocnemius region.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    20550Injection(s); single or multiple trigger point(s), 1 or 2 muscle(s)Used prior to surgery for diagnostic relief or conservative management of focal gastrocnemius spasms.
    20552Injection(s); trigger point(s), more than 2 muscle(s)Used when multiple muscles are targeted for nonoperative spasm management.
    20560Injection, therapeutic, including anesthetic agent; tendon sheath, ligament, ganglion cystOccasionally used for diagnostic or adjunct injections around the posterior knee.
    95886Needle electromyography; 1 extremity with or without related paraspinal areas, 1–2 musclesPreoperative EMG studies to localize nerve hyperactivity contributing to spasms.
    95885Needle electromyography; 1 extremity with or without related paraspinal areas, 3–4 musclesAlternate EMG study code when more muscles are studied for localization.
    64450Injection, anesthetic agent; sciatic nerve, singlePerioperative or diagnostic nerve block of the sciatic nerve for pain control or localization prior to definitive excision.
    27759Other open or percutaneous incisions or excisions of lesion of popliteal area (example code)Related soft-tissue or lesion excisions in the popliteal region that may be performed in the same operative session.

    Related Modifiers

    10 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    73Modifier 73 indicates a facility-level outpatient hospital or ASC procedure that was discontinued after the patient was prepared and taken to the procedure/operating room but before any anesthesia…- When to use: Apply CPT modifier 73 on the FACILITY (outpatient hospital or ASC) claim when the patient has been fully prepared and physically taken into the procedure/operating room but the…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207L00000X
    2080P0205X
    207X00000X
    213E00000X
    2088P0231X
    225C00000X
    246ZX2200X
    163WP1700X

    Related Payer Policy Updates

    Specialty: General Surgery1 / 3

    10 rows

    PolicyPayerEffective Date
    Removal of ImplantableBlue Cross Blue Shield - Rhode Island2026-10-01
    Outpatient Surgical Procedures - Site of ServiceUnitedHealthcare2026-09-01
    Surgical ProceduresUnitedHealthcare2026-09-01
    Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Site of Service for Ambulatory Surgical Procedures (ASC Select)Premera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Medical Necessity Guidelines Inpatient Surgical CareMass General Brigham Health Plan2026-08-01
    Outpatient Surgical Procedures - Site of Servicesierra health and life2026-08-01

    Related Codes

    CPT-27323-EXCISIONAL-BIOPSY-THIGH-KNEE-SUPERFICIAL-SOFT-TISSUE

    CPT 27323: Excisional Biopsy of Superficial Soft Tissue, Thigh or Knee

    CPT-27324-DEEP-SOFT-TISSUE-BIOPSY-THIGH-KNEE

    CPT 27324: Deep Tissue/Muscle Biopsy of Thigh or Knee

    CPT-27325-HAMSTRING-NEURECTOMY-NERVE-EXCISION

    CPT 27325: Neurectomy of Nerve Along Hamstring

    CPT-27327-SUBCUTANEOUS-TUMOR-EXCISION-THIGH-KNEE

    CPT 27327: Excision of Subcutaneous Tumor of Thigh or Knee (<3 cm)

    CPT-27328-INTRAMUSCULAR-THIGH-KNEE-TUMOR-EXCISION-SMALL

    CPT 27328: Excision of Intramuscular Tumor of Thigh or Knee (<5 cm)

    CPT-27329-EXTENSIVE-EXCISION-SOFT-TISSUE-TUMOR-THIGH-KNEE-LESS-5CM

    CPT 27329: Extensive Excision of Soft-Tissue Tumor, Thigh/Knee (<5 cm)

    CPT-27330-KNEE-SYNOVIAL-BIOPSY-SURGICAL-DIAGNOSTIC

    CPT 27330: Open Biopsy of Synovium of Knee

    CPT-27331-KNEE-ARTHROTOMY-BIOPSY-LOOSE-BODY-REMOVAL

    CPT 27331: Knee Arthrotomy with Synovial Biopsy and Loose Body Removal

    CPT-27332-KNEE-ARTHROTOMY-MENISCAL-EXCISION

    CPT 27332: Arthrotomy with Excision of Medial or Lateral Meniscus

    CPT-27333-KNEE-PARTIAL-MENISCECTOMY-MEDIAL-AND-LATERAL

    CPT 27333: Meniscectomy, Medial and Lateral Knee

    Showing 1–10 of 25

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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