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    v1.0.30
    OpenPayerBilling CodesExcision Procedures on the Back and FlankCPT cpt-21933-subfascial-soft-tissue-tumor-excision-back-flank-5cm-plus
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    CPT 21933: Subfascial Soft Tissue Tumor Excision, Back or Flank (≥5 cm)

    Medicare pays $709 on average nationally for this procedure.

    CPT code 21933 describes a physician service for excision of a subfascial soft tissue tumor measuring 5 cm or larger located on the back or flank; service type: surgical excision of deep soft tissue tumor; typical site of service: inpatient or outpatient hospital surgical setting or ambulatory surgery center where deep soft tissue tumor resections are performed.

    For related coverage guidance, see recent payer policy updates: Destruction of Pre-Malignant Skin Lesions, Onychomycosis diagnostic testing and coverage, Treatment of Capillary Malformations (Port Wine Stains).

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 58-year-old male presents to the surgical clinic with a progressively enlarging, painless soft tissue mass on the left paraspinal region of the back. Physical exam demonstrates a palpable, deep-seated nodule fixed beneath the fascia and measuring clinically greater than 5 cm. Imaging with MRI of the back confirms a 6.2 cm subfascial soft tissue tumor without obvious invasion of underlying bony structures. The patient is evaluated by an orthopedic oncology or general surgical oncologist who obtains informed consent for excision. Preoperative workflow includes history and physical, review of imaging, perioperative medical clearance, marking the operative site, and documentation of tumor size and location. In the operating room under general anesthesia, the surgeon makes an incision over the lesion, dissects through subcutaneous tissue, identifies and opens the fascia, and performs a subfascial soft tissue tumor excision with margin control. Hemostasis is achieved, drains are placed as indicated, and the fascia and skin are closed. Postoperative care includes monitoring in the PACU, wound care instructions, pathology specimen submission with tumor dimensions, and follow-up for wound check and pathology review.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    11042Debridement; subcutaneous tissue (includes epidermis and dermis when performed)May be used if extensive debridement of subcutaneous tissue is required in the same operative session as 21933.
    20220Excision, tumor; subcutaneous tissue (any depth)Related for excision of soft tissue tumors; 21933 specifically addresses subfascial tumors ≥5 cm on back or flank, while 20220 covers different anatomic sites and depths.
    19318Reduction mammoplasty; simpleData not available in the input.
    12032Repair, intermediate, wounds of trunk 2.6 cm to 7.5 cmUsed for layered, intermediate closure of the skin and subcutaneous tissues after tumor excision when sized within the code range.
    11043Debridement; muscle and/or fasciaApplicable if necrotic muscle or fascia must be debrided in conjunction with 21933.
    20926Tissue grafts; allograft, femoral head or otherData not available in the input.

    Related Modifiers

    14 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    24Modifier 24 denotes an unrelated evaluation and management (E/M) service performed by the same physician or qualified healthcare professional during a postoperative global period. Per CPT guidance,…- Use modifier 24 when you report an evaluation and management (E/M) service performed by the same physician or same-specialty group during a procedure’s postoperative global period that is unrelated…
    25CPT modifier 25 indicates that on the same day as another procedure or service, the same physician or other qualified health care professional provided a significant, separately identifiable…- When to apply: Use modifier 25 only on an E/M code to indicate the same provider delivered a significant, separately identifiable E/M service on the same day as another procedure or service — i.e.,…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    58Modifier 58 (Staged or related procedure/service by the same physician during the postoperative period) indicates that a subsequent procedure performed by the same provider during the…- Use modifier 58 when the same physician/QHP performs a procedure during the postoperative/global period of an earlier procedure and the subsequent procedure is either planned or anticipated…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…

    Showing 1–10 of 14

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    363AM0700X
    261QX0200X
    311Z00000X
    101YA0400X
    376G00000X
    246QI0000X
    213EP1101X
    175M00000X

    Related ICD-10-CM Codes

    22 rows

    ICD-10-CM CodeDescription
    C49.5Malignant neoplasm of connective and soft tissue of pelvis
    D48.5Neoplasm of uncertain behavior of skin
    D49.2Neoplasm of unspecified behavior of bone, soft tissue, and skin
    L03.116Cellulitis of left lower limb
    L03.119Cellulitis of unspecified part of limb
    L91.8Other hypertrophic disorders of the skin
    L92.8Other granulomatous disorders of the skin and subcutaneous tissue
    L94.0Localized scleroderma [morphea]
    L98.9Disorder of the skin and subcutaneous tissue, unspecified
    M60.9Myositis, unspecified

    Showing 1–10 of 22

    Related Payer Policy Updates

    Specialty: Dermatology1 / 3

    10 rows

    PolicyPayerEffective Date
    Destruction of Pre-Malignant Skin LesionsAnthem2026-10-01
    Onychomycosis diagnostic testing and coverageOscar Health2026-10-01
    Treatment of Capillary Malformations (Port Wine Stains)universityofutahhealthplans2026-09-28
    AnzupgoCigna2026-09-15
    Zevaskyn Coverage for Recessive Dystrophic Epidermolysis BullosaCigna2026-09-01
    Topical Acne-Non-Retinoid ProductsCigna2026-08-15
    Dermatology - Vtama Drug Quantity Management Policy - Per DaysCigna2026-08-15
    Medical Necessity Guidelines: Acne and Rosacea Medicationsharvard pilgrim health care2026-08-11
    Dermatology - Anzupgo Prior Authorization PolicyCigna2026-08-05
    Light Therapy for Dermatologic Conditionsbcbsvermont2026-08-01

    Related Codes

    CPT-21920-SUPERFICIAL-SOFT-TISSUE-BIOPSY-BACK-FLANK

    CPT 21920: Superficial Soft Tissue Biopsy of Back or Flank

    CPT-21925-DEEP-SOFT-TISSUE-BIOPSY-BACK-FLANK

    CPT 21925: Deep Soft Tissue Biopsy of Back or Flank

    CPT-21930-SOFT-TISSUE-MASS-EXCISION-BACK-FLANK-LESS-THAN-3CM

    CPT 21930: Excision of Subcutaneous Soft-Tissue Lesion, Back/Flank (<3 cm)

    CPT-21931-SOFT-TISSUE-EXCISION-BACK-FLANK-3CM-OR-GREATER

    CPT 21931: Excision of Soft Tissue Mass of Back/Flank ≥3 cm

    CPT-21932-SUBFASCIAL-SOFT-TISSUE-TUMOR-EXCISION-BACK-FLANK

    CPT 21932: Subfascial Soft Tissue Tumor Excision, Back/Flank (<5 cm)

    CPT-21935-EXTENSIVE-EXCISION-SOFT-TISSUE-TUMOR-BACK-FLANK-LESS-5CM

    CPT 21935: Extensive Excision of Malignant Soft Tissue Tumor, Back/Flank <5cm

    CPT-21936-EXTENSIVE-EXCISION-SOFT-TISSUE-SARCOMA-BACK-FLANK-5CM

    CPT 21936: Extensive Excision of Large Soft Tissue Malignant Tumor

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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