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    v1.0.28
    OpenPayerBilling CodesGeneral Introduction or Removal Procedures on the Musculoskeletal SystemCPT cpt-20605-needle-aspiration-injection-intermediate-joint-bursa
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    CPT 20605: Arthrocentesis or Injection of Intermediate Joint/Bursa, No Ultrasound

    Medicare pays $59 on average nationally for this procedure.

    CPT code 20605 describes a procedure in which a provider inserts a needle through the skin into an intermediate joint or bursa to aspirate fluid or inject a therapeutic drug without ultrasound guidance; service type: arthrocentesis/therapeutic or diagnostic joint or bursa injection; typical site of service: office, outpatient clinic, or ambulatory procedure setting.

    For related coverage guidance, see recent payer policy updates: Shoulder Arthroplasty (Total, Partial, Reverse, Revision and Resurfacing), Hip Arthroplasty (partial and total hip replacement), Artificial Lumbar Intervertebral Disc (Lumbar Total Disc Arthroplasty).

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 56-year-old patient presents to an outpatient orthopedics clinic with a 2-week history of progressive swelling, pain, and reduced range of motion in the right knee. The clinician performs a focused history and musculoskeletal exam, noting joint effusion and crepitus. Point-of-care imaging (plain radiographs) rules out acute fracture; ultrasound is available but not used for the procedure. After informed consent, the provider performs an aseptic joint aspiration (arthrocentesis) of the knee using a sterile needle and syringe to remove synovial fluid for diagnostic analysis and relieves pressure. The clinician may then inject an intra-articular corticosteroid for therapeutic effect during the same encounter. The procedure is performed in an outpatient clinic procedure room or urgent care setting; standard documentation includes indication, neurovascular status of the extremity, technique (needle gauge, approach), amount and character of fluid obtained, any medication injected (name, dose, lot), patient tolerance, and post-procedure instructions.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    20610Arthrocentesis, aspiration and/or injection; major joint or bursa (e.g., shoulder, elbow, hip, knee joint)Often used interchangeably when site is a major joint; choose based on CPT definitions and documentation of joint treated.
    20600Arthrocentesis, aspiration and/or injection; small joint (e.g., fingers, toes)Performed for smaller synovial joints when appropriate instead of intermediate-joint code.
    20550Injection(s); single tendon sheath, or ligament, aponeurosis (e.g., trigger finger)Performed when injection targets tendon sheath rather than the joint space.
    99000Handling and/or conveyance of specimen for transfer from the physician to a qualified laboratoryUse when provider documents transfer of synovial fluid to outside laboratory; facility or payor rules may affect billing.
    96372Therapeutic, prophylactic, or diagnostic injection (specify substance)May be reported for separate drug administration if not considered integral to the arthrocentesis per payer rules.

    Related Modifiers

    12 rows

    ModifierDescriptionWhen to Use
    25CPT modifier 25 indicates that on the same day as another procedure or service, the same physician or other qualified health care professional provided a significant, separately identifiable…- When to apply: Use modifier 25 only on an E/M code to indicate the same provider delivered a significant, separately identifiable E/M service on the same day as another procedure or service — i.e.,…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    77Modifier 77 indicates that a previously performed procedure or service was legitimately repeated by a different physician or other qualified health care professional. The AMA’s CPT definition…- Use modifier 77 when a basic procedure or service already performed is repeated by a different physician or other qualified health care professional (for example, a second provider independently…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…

    Showing 1–10 of 12

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    246ZE0600XElectroneurodiagnostic Specialist/TechnologistTechnologists, Technicians & Other Technical Service Providers · Specialist/Technologist, Other
    207YX0905XOtolaryngology/Facial Plastic Surgery PhysicianAn otolaryngologist who specializes in the diagnosis and surgical treatment of head and neck conditions.
    124Q00000XDental HygienistAn individual who has completed an accredited dental hygiene education program, and an individual who has been licensed by a state board of dental exa…
    163WC3500XCardiac Rehabilitation Registered NurseNursing Service Providers · Registered Nurse
    363LG0600XGerontology Nurse PractitionerPhysician Assistants & Advanced Practice Nursing Providers · Nurse Practitioner
    207WX0009XGlaucoma Specialist (Ophthalmology) PhysicianAn ophthalmologist who specializes in the treatment of glaucoma and other disorders related to increased intraocular pressure and optic nerve damage. …
    2086S0120XPediatric Surgery PhysicianA surgeon with expertise in the management of surgical conditions in premature and newborn infants, children and adolescents.
    363L00000XNurse Practitioner(1) A registered nurse provider with a graduate degree in nursing prepared for advanced practice involving independent and interdependent decision mak…

    Related ICD-10-CM Codes

    25 rows

    ICD-10-CM CodeDescription
    A18.84Tuberculosis of heart
    M17.11Unilateral primary osteoarthritis, right knee
    M17.12Unilateral primary osteoarthritis, left knee
    M19.011Primary osteoarthritis, right shoulder
    M19.012Primary osteoarthritis, left shoulder
    M20.11Hallux valgus (acquired), right foot
    M24.571Contracture, right ankle
    M24.572Contracture, left ankle
    M25.50Pain in unspecified joint
    M25.551Pain in right hip

    Showing 1–10 of 25

    Related Payer Policy Updates

    Specialty: Orthopedics/Musculoskeletal1 / 3

    10 rows

    PolicyPayerEffective Date
    Shoulder Arthroplasty (Total, Partial, Reverse, Revision and Resurfacing)univerahealthcare2026-10-15
    Hip Arthroplasty (partial and total hip replacement)univerahealthcare2026-10-15
    Artificial Lumbar Intervertebral Disc (Lumbar Total Disc Arthroplasty)univerahealthcare2026-10-15
    Osteochondral Grafting of the Kneeuniverahealthcare2026-10-15
    Metal-on-Metal Total Hip Resurfacinguniverahealthcare2026-10-15
    Lumbar Fusion (arthrodesis) with decompressionuniverahealthcare2026-10-15
    Sacroiliac Joint Fusion or Stabilizationuniverahealthcare2026-10-15
    Percutaneous Vertebroplasty/Mechanical Vertebral Augmentation and Percutaneous Sacroplastyuniverahealthcare2026-10-15
    Autologous Chondrocyte Implantation (ACI)univerahealthcare2026-10-15
    Shoulder Open ProceduresPremera Bluecross2026-09-04

    Related Codes

    CPT-20500-SINUS-TRACT-THERAPEUTIC-INJECTION

    CPT 20500: Injection of Therapeutic Agent into Sinus Tract

    CPT-20501-SINUS-TRACT-CONTRAST-INJECTION-DIAGNOSTIC

    CPT 20501: Sinus Tract Contrast Injection for Abscess/Lesion Evaluation

    CPT-20520-FOREIGN-BODY-REMOVAL-MUSCLE-TENDON-SHEATH

    CPT 20520: Removal of Foreign Body From Muscle or Tendon Sheath

    CPT-20525-DEEP-FOREIGN-BODY-REMOVAL-MUSCLE-TENDON-SHEATH

    CPT 20525: Deep Foreign Body Removal from Muscle or Tendon Sheath

    CPT-20526-CARPAL-TUNNEL-INJECTION-SHORT-TERM-RELIEF

    CPT 20526: Injection for Carpal Tunnel Syndrome

    CPT-20527-COLLAGENASE-INJECTION-DUPUYTRENS-CONTRACTURE

    CPT 20527: Collagenase Injection for Dupuytren's Contracture

    CPT-20550-TENDON-OR-LIGAMENT-INJECTION-APONEUROSIS-TREATMENT

    CPT 20550: Injection into Tendon or Ligament for Aponeurosis

    CPT-20551-TENDON-ORIGIN-INSERTION-INJECTION

    CPT 20551: Injection into Tendon Origin or Insertion Site

    CPT-20552-TRIGGER-POINT-INJECTION-ONE-OR-TWO-MUSCLES

    CPT 20552: Trigger Point Injection for Myofascial Pain

    CPT-20553-TRIGGER-POINT-INJECTION-THREE-OR-MORE-MUSCLES

    CPT 20553: Trigger Point Injection, Three or More Muscles

    Showing 1–10 of 41

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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