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    OpenPayerBilling CodesAblation, Exploration and Excision ProceduresCPT cpt-19126-additional-excision-marked-breast-lesion
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    CPT 19126: Excision of Additional Localized Breast Lesion

    Medicare pays $144 on average nationally for this procedure.

    CPT code 19126 describes excision of an additional breast lesion previously localized with a preoperative radiological marker, performed through an open incision after removal of an initial lesion; this is a surgical breast procedure for lesion excision (additional lesion) and is typically provided in an outpatient surgical or ambulatory surgery center setting or hospital outpatient department.

    For related coverage guidance, see recent payer policy updates: Removal of Implantable, Outpatient Surgical Procedures - Site of Service, Surgical Procedures.

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    Clinical & Coding Specifications

    Clinical Context

    A patient with a suspicious breast lesion previously localized preoperatively with a radiological marker (wire or seed) undergoes surgical excision of that primary lesion. During the same operative session the surgeon identifies an additional radiographically marked lesion in the same breast and performs a second open excision through a separate incision or an extension of the original incision to remove the additional lesion. Typical patients are adult females evaluated for imaging abnormalities such as a new mass, calcifications, or biopsy-proven high-risk lesions who have had preoperative localization. The workflow includes preoperative imaging and localization by radiology, intraoperative specimen radiography as needed to confirm removal of the marker and lesion, pathological submission of separate specimens with labels identifying laterality and specimen sequence, and operative note documentation describing the presence of the additional localized lesion, the technique used to excise it, and confirmation that the preoperative radiologic marker was removed.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    19125Excision of breast lesion identified by preoperative placement of radiological marker, open; first lesionPerformed immediately before or alongside 19126 when removing the first localized lesion from the same breast
    19301Mastectomy, partial (partial mastectomy, lumpectomy)May be used if the surgical plan requires a wider excision or partial mastectomy encompassing lesion(s) beyond localized excisions
    19290Localization procedure for lesion(s) of breast, placement of localization device (e.g., wire, seed)Performed preoperatively by radiology to localize lesions that are later excised with 19125/19126
    76085Mammography, previous radiographic comparison and preoperative localization, breast, each lesion, image-guidedImaging support during localization and intraoperative specimen radiograph correlation
    88305Surgical pathology, gross and microscopic examination, level IVCommon pathology code for tissue sections of excised breast lesions submitted after 19126

    Related Modifiers

    8 rows

    ModifierDescriptionWhen to Use
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    253J00000X
    208M00000X
    246XS1301X
    207WX0110X
    1744P3200X
    261QR0800X
    163WX0002X
    225CA2400X

    Related ICD-10-CM Codes

    23 rows

    ICD-10-CM CodeDescription
    C50.111Malignant neoplasm of central portion of right female breast
    C50.112Malignant neoplasm of central portion of left female breast
    C50.119Malignant neoplasm of central portion of unspecified female breast
    C50.212Malignant neoplasm of upper-inner quadrant of left female breast
    C50.311Malignant neoplasm of lower-inner quadrant of right female breast
    C50.411Malignant neoplasm of upper-outer quadrant of right female breast
    C50.511Malignant neoplasm of lower-outer quadrant of right female breast
    C50.611Malignant neoplasm of axillary tail of right female breast
    C50.811Malignant neoplasm of overlapping sites of right female breast
    C50.821Malignant neoplasm of overlapping sites of right male breast

    Showing 1–10 of 23

    Related Payer Policy Updates

    Specialty: General Surgery1 / 2

    10 rows

    PolicyPayerEffective Date
    Removal of ImplantableBlue Cross Blue Shield - Rhode Island2026-10-01
    Outpatient Surgical Procedures - Site of ServiceUnitedHealthcare2026-09-01
    Surgical ProceduresUnitedHealthcare2026-09-01
    Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Site of Service for Ambulatory Surgical Procedures (ASC Select)Premera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Medical Necessity Guidelines Inpatient Surgical CareMass General Brigham Health Plan2026-08-01
    Outpatient Surgical Procedures - Site of Servicesierra health and life2026-08-01

    Related Codes

    CPT-19105-BREAST-FIBROADENOMA-CRYOABLATION-ULTRASOUND-GUIDED

    CPT 19105: Ultrasound-Guided Cryoablation of Fibroadenoma

    CPT-19110-EXCISION-SINGLE-LACTIFEROUS-DUCT-PAPILLOMA

    CPT 19110: Nipple Exploration with Excision of Single Lactiferous Duct

    CPT-19112-EXCISION-LACTIFEROUS-DUCT-SKIN-FISTULA

    CPT 19112: Excision of Lactiferous Duct–Skin Fistula

    CPT-19120-OPEN-EXCISION-SUSPICIOUS-BREAST-LESION

    CPT 19120: Excision of Suspicious Breast Lesion, Open Approach

    CPT-19125-EXCISION-SINGLE-RADIOLOGICALLY-LOCALIZED-LESION

    CPT 19125: Excision of Single Radiologically Marked Lesion

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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