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    v1.0.30
    OpenPayerBilling CodesAblation, Exploration and Excision ProceduresCPT cpt-19105-breast-fibroadenoma-cryoablation-ultrasound-guided
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    CPT 19105: Ultrasound-Guided Cryoablation of Fibroadenoma

    Medicare pays $2651 on average nationally for this procedure.

    CPT code 19105 describes ultrasound-guided cryoablation of a fibroadenoma, a procedure in which a provider uses a cryoprobe to destroy a benign solid breast tumor; service type: image-guided percutaneous ablative procedure; typical site of service: outpatient imaging suite or ambulatory surgery center (breast procedure performed under ultrasound guidance).

    For related coverage guidance, see recent payer policy updates: Removal of Implantable, Outpatient Surgical Procedures - Site of Service, Surgical Procedures.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 34-year-old woman presents with a palpable, well-circumscribed breast mass previously proven by core needle biopsy to be a benign fibroadenoma. The mass measures 1.8 cm on diagnostic ultrasound and the patient requests a minimally invasive, cosmetically favorable option for lesion removal. The breast surgeon schedules an outpatient ultrasound-guided cryoablation procedure using a cryoprobe under local anesthesia with conscious sedation as needed. The clinical workflow includes pre-procedure imaging confirmation and consent, time-out and sterile preparation in an ambulatory surgery center or hospital outpatient department, ultrasound localization of the target lesion, percutaneous cryoprobe insertion, two freeze–thaw cycles to ablate the fibroadenoma under real-time ultrasound visualization, post-procedure hemostasis and dressing, brief recovery monitoring, and discharge with return precautions and follow-up arranged for imaging at 3–6 months.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    76942Ultrasonic guidance for needle placement (e.g., for diagnostic or therapeutic injection)Performed to localize the fibroadenoma and guide cryoprobe placement under real-time ultrasound.
    19083Biopsy, percutaneous, breast, with placement of needle-localization device(s) when performed; with imaging guidanceMay precede cryoablation if a prior core biopsy or localization is required in the same session.
    20550Injection(s); single tendon sheath, or ligament, or trigger point — therapeutic (included as example of injection code)Local anesthetic or corticosteroid injections are rarely used peri-procedurally for pain control; included only when adjunctive injections occur.
    99213Office or other outpatient visit for the evaluation and management of an established patient, typically 15 minutesCommonly used for pre-procedure evaluation or post-procedure follow-up visits in the outpatient setting.
    36415Collection of venous blood by venipuncturePerformed when laboratory testing (e.g., coagulation studies) is obtained pre-procedure.

    Related Modifiers

    8 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207X00000X
    207RC0000X
    363L00000X
    2255A2300X
    207YX0905X
    2085R0203X
    2355A2700X
    246Z00000X

    Related Payer Policy Updates

    Specialty: General Surgery1 / 2

    10 rows

    PolicyPayerEffective Date
    Removal of ImplantableBlue Cross Blue Shield - Rhode Island2026-10-01
    Outpatient Surgical Procedures - Site of ServiceUnitedHealthcare2026-09-01
    Surgical ProceduresUnitedHealthcare2026-09-01
    Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Site of Service for Ambulatory Surgical Procedures (ASC Select)Premera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Medical Necessity Guidelines Inpatient Surgical CareMass General Brigham Health Plan2026-08-01
    Outpatient Surgical Procedures - Site of Servicesierra health and life2026-08-01

    Related Codes

    CPT-19110-EXCISION-SINGLE-LACTIFEROUS-DUCT-PAPILLOMA

    CPT 19110: Nipple Exploration with Excision of Single Lactiferous Duct

    CPT-19112-EXCISION-LACTIFEROUS-DUCT-SKIN-FISTULA

    CPT 19112: Excision of Lactiferous Duct–Skin Fistula

    CPT-19120-OPEN-EXCISION-SUSPICIOUS-BREAST-LESION

    CPT 19120: Excision of Suspicious Breast Lesion, Open Approach

    CPT-19125-EXCISION-SINGLE-RADIOLOGICALLY-LOCALIZED-LESION

    CPT 19125: Excision of Single Radiologically Marked Lesion

    CPT-19126-ADDITIONAL-EXCISION-MARKED-BREAST-LESION

    CPT 19126: Excision of Additional Localized Breast Lesion

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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