ICD-10-PCS Code For Spleen: Procedure Code Group Overview

The International Classification of Diseases, Tenth Revision, Procedure Coding System (ICD-10-PCS) code group C722 includes procedures performed to image tissues using tomographic nuclear medicine techniques in the spleen. These ICD-10-PCS codes are used for inpatient documentation when three dimensional nuclear medicine imaging with introduced radioactive materials is performed to evaluate splenic anatomy or function. Accurate coding within the ICD-10-PCS C722 group is essential for proper inpatient reimbursement, as it captures the specific imaging modality performed and supports clinical documentation accuracy.

Customize your policy alerts

Sign up for ICD-10-PCS Code For Spleen: Procedure Code Group Overview policy alerts

Get alerted when relevant policies change without checking for updates manually.

Monitor payer policy activity

Receive email alerts as soon as relevant payer policies are published or updated.

Spleen Tomographic Nuclear Medicine Imaging Procedure Overview

This procedure group includes tomographic nuclear medicine imaging studies of the spleen that use introduced radioactive materials to create three dimensional images from emitted radiation. These procedures target the lymphatic and hematologic system and involve capturing and reconstructing radioactive emissions for diagnostic evaluation of splenic structure and function. Accurate ICD-10-PCS coding ensures the inpatient record reflects the imaging modality used and supports appropriate case mix assignment and reimbursement.

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
C	Section	Nuclear Medicine
7	Body System	Lymphatic and Hematologic System
2	Operation	Tomographic (Tomo) Nuclear Medicine Imaging
2	Body Part	Spleen

Explore openpayer tools

View all tools

ICD-10-PCS Code For Spleen: Procedure Code Group Overview

Customize your policy alerts

Sign up for ICD-10-PCS Code For Spleen: Procedure Code Group Overview policy alerts

Get alerted when relevant policies change without checking for updates manually.

Monitor payer policy activity

Receive email alerts as soon as relevant payer policies are published or updated.

Spleen Tomographic Nuclear Medicine Imaging Procedure Overview

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
C	Section	Nuclear Medicine
7	Body System	Lymphatic and Hematologic System
2	Operation	Tomographic (Tomo) Nuclear Medicine Imaging
2	Body Part	Spleen

When to Use

Use codes from this group when inpatient care includes tomographic nuclear medicine imaging of the spleen with introduction of a radioactive tracer to obtain three dimensional emission images. These codes apply when the study is performed to assess splenic perfusion, function, or to localize pathology using nuclear imaging techniques.

ICD-10-PCS Codes

2 rows

ICD-10-PCS Code	Description
C7221ZZ	Tomographic (Tomo) Nuclear Medicine Imaging of Spleen using Technetium 99m (Tc-99m)
C722YZZ	Tomographic (Tomo) Nuclear Medicine Imaging of Spleen using Other Radionuclide

Typical Clinical Scenarios

An adult patient is admitted with acute left upper quadrant pain and fever after blunt abdominal trauma; clinicians suspect splenic laceration with compromised perfusion and need to assess viable splenic tissue and regional blood flow before deciding on operative versus nonoperative management, so tomographic nuclear medicine imaging of the spleen using an introduced radiotracer is performed to evaluate splenic perfusion. Typical codes: C7221ZZ, C722YZZ
An elderly patient with a history of lymphoma is admitted for staging and evaluation of suspected splenic involvement after abnormal CT findings; inpatient tomographic nuclear medicine imaging of the spleen with a radiotracer is obtained to characterize splenic uptake and differentiate infiltrative disease from benign changes as part of the diagnostic workup. Typical codes: C7221ZZ, C722YZZ
A postoperative patient on the inpatient service develops unexplained persistent anemia and splenomegaly after recent oncologic therapy; to evaluate functional splenic sequestration versus focal splenic defects that might explain ongoing blood cell destruction, a tomographic nuclear medicine spleen study with an injected radionuclide is performed to localize functional tissue and guide further management. Typical codes: C7221ZZ, C722YZZ

ICD-10-PCS Code For Lymphatic And Hematologic System: Procedure Code Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.

Explore openpayer tools

View all tools

When to Use

ICD-10-PCS Codes

2 rows

ICD-10-PCS Code	Description
C7221ZZ	Tomographic (Tomo) Nuclear Medicine Imaging of Spleen using Technetium 99m (Tc-99m)
C722YZZ	Tomographic (Tomo) Nuclear Medicine Imaging of Spleen using Other Radionuclide

Typical Clinical Scenarios

An adult patient is admitted with acute left upper quadrant pain and fever after blunt abdominal trauma; clinicians suspect splenic laceration with compromised perfusion and need to assess viable splenic tissue and regional blood flow before deciding on operative versus nonoperative management, so tomographic nuclear medicine imaging of the spleen using an introduced radiotracer is performed to evaluate splenic perfusion. Typical codes: C7221ZZ, C722YZZ
An elderly patient with a history of lymphoma is admitted for staging and evaluation of suspected splenic involvement after abnormal CT findings; inpatient tomographic nuclear medicine imaging of the spleen with a radiotracer is obtained to characterize splenic uptake and differentiate infiltrative disease from benign changes as part of the diagnostic workup. Typical codes: C7221ZZ, C722YZZ
A postoperative patient on the inpatient service develops unexplained persistent anemia and splenomegaly after recent oncologic therapy; to evaluate functional splenic sequestration versus focal splenic defects that might explain ongoing blood cell destruction, a tomographic nuclear medicine spleen study with an injected radionuclide is performed to localize functional tissue and guide further management. Typical codes: C7221ZZ, C722YZZ

ICD-10-PCS Code For Lymphatic And Hematologic System: Procedure Code Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

OpenPayer

ICD-10-PCS Code For Spleen: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Spleen: Procedure Code Group Overview policy alerts

Spleen Tomographic Nuclear Medicine Imaging Procedure Overview

Code Attributes

OpenPayer

ICD-10-PCS Code For Spleen: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Spleen: Procedure Code Group Overview policy alerts

Spleen Tomographic Nuclear Medicine Imaging Procedure Overview

Code Attributes

When to Use

ICD-10-PCS Codes

Typical Clinical Scenarios

Related Codes

References

When to Use

ICD-10-PCS Codes

Typical Clinical Scenarios

Related Codes

References

ICD-10-PCS Code For Spleen: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Spleen: Procedure Code Group Overview policy alerts

Spleen Tomographic Nuclear Medicine Imaging Procedure Overview

Code Attributes

ICD-10-PCS Code For Spleen: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Spleen: Procedure Code Group Overview policy alerts

Spleen Tomographic Nuclear Medicine Imaging Procedure Overview

Code Attributes

When to Use

ICD-10-PCS Codes

Typical Clinical Scenarios

Related Codes

Which procedures are included in the ICD-10-PCS C722 code group?

What is the ICD-10-PCS section and body system for C722 codes?

When should C722 codes be used in inpatient documentation?

How do C722 codes affect reimbursement and case mix assignment?

What radionuclide options are specified within the C722 code group?

References

When to Use

ICD-10-PCS Codes

Typical Clinical Scenarios

Related Codes

Which procedures are included in the ICD-10-PCS C722 code group?

What is the ICD-10-PCS section and body system for C722 codes?

When should C722 codes be used in inpatient documentation?

How do C722 codes affect reimbursement and case mix assignment?

What radionuclide options are specified within the C722 code group?

References