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    v1.0.28
    OpenPayerBilling CodesMalignant neoplasms of male genital organsICD-10-CM c61-malignant-neoplasm-of-prostate
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    ICD-10-CM Code For Malignant Neoplasm Of Prostate: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group C61 includes malignant neoplasms of the prostate, covering primary prostate cancer and related tumor involvement of adjacent structures. These ICD-10-CM diagnosis codes are used to document clinical scenarios such as initial diagnosis, disease progression, local invasion, or metastatic spread involving the prostate gland. Accurate coding within the ICD-10-CM C61 group supports proper claim adjudication and complete clinical documentation and appropriate reimbursement.

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    ICD-10-CM C61: Malignant Neoplasm Of Prostate Overview

    This group represents malignant tumors originating in the prostate gland, a male reproductive organ. The diagnoses target prostate cancer and related local invasion or metastatic involvement. Accurate coding matters for clinical records, quality reporting, and appropriate reimbursement determination.

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    When to Use

    Use a code from this group when a diagnosis of prostate cancer has been established and documented by the treating clinician. Select the specific code that reflects disease site, laterality if applicable, and documented presence of invasion or metastasis.

    ICD-10-CM Codes

    1 rows

    ICD-10-CM CodeDescription
    C61Malignant neoplasm of prostate

    DRG Codes

    5 rows

    DRG CodeDescription
    715Other Male Reproductive System O.R. Procedures for Malignancy with CC/MCC
    716Other Male Reproductive System O.R. Procedures for Malignancy without CC/MCC
    722Malignancy, Male Reproductive System with MCC
    723Malignancy, Male Reproductive System with CC
    724Malignancy, Male Reproductive System without CC/MCC

    Typical Clinical Scenarios

    • An older male with progressive urinary hesitancy, weak stream, nocturia, and a rising prostate-specific antigen (PSA) over serial testing presents to urology for evaluation; digital rectal exam reveals a firm nodule and transrectal ultrasound-guided biopsy confirms adenocarcinoma of the prostate, so a malignant prostate neoplasm diagnosis is assigned. Typical codes: C61.
    • A middle-aged man undergoing staging after initial prostate cancer diagnosis presents for evaluation of bone pain and imaging shows metastatic lesions to the lumbar spine; the clinical encounter documents prostate malignancy with evidence of metastatic spread, so the prostate cancer code is recorded as the principal malignancy driving care. Typical codes: C61.
    • An elderly male with known treated prostate cancer is admitted with urinary retention and hematuria related to tumor progression and local invasion of the bladder outlet; because the current hospitalization is for complications attributable to the prostate malignancy, the malignant prostate neoplasm diagnosis is assigned as a relevant underlying condition. Typical codes: C61.

    Related Codes

    C60-MALIGNANT-NEOPLASM-OF-PENIS

    ICD-10-CM Code For Malignant Neoplasm Of Penis: Group Overview

    C62-MALIGNANT-NEOPLASM-OF-TESTIS

    ICD-10-CM Code For Malignant Neoplasm Of Testis: Group Overview

    C63-MALIGNANT-NEOPLASM-MALE-GENITAL

    ICD-10-CM Code For Malignant Neoplasm Of Other And Unspecified Male Genital Organs: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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