ICD-10-PCS Code For Central Nervous System: Procedure Code Group Overview

The International Classification of Diseases, Tenth Revision, Procedure Coding System (ICD-10-PCS) code group C05Y includes procedures performed to introduce radioactive materials for study of distribution and emissions in the central nervous system. These ICD-10-PCS codes are used for inpatient documentation when a nonimaging nuclear medicine probe study is performed to evaluate central nervous system function or tracer distribution. Accurate coding within the ICD-10-PCS C05Y group is essential for proper inpatient reimbursement, as it captures the procedure performed and determines appropriate case mix and payment.

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Central Nervous System Nonimaging Nuclear Medicine Probe Procedure Overview

Procedures in this group involve nonimaging nuclear medicine probe studies that introduce radioactive material to evaluate the central nervous system. These procedures target the central nervous system and measure distribution or emissions without producing diagnostic images. Accurate ICD-10-PCS coding ensures inpatient records reflect the specific procedure performed and supports appropriate case mix and payment.

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
C	Section	Nuclear Medicine
0	Body System	Central Nervous System
5	Operation	Nonimaging Nuclear Medicine Probe
Y	Body Part	Central Nervous System

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ICD-10-PCS Code For Central Nervous System: Procedure Code Group Overview

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Central Nervous System Nonimaging Nuclear Medicine Probe Procedure Overview

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
C	Section	Nuclear Medicine
0	Body System	Central Nervous System
5	Operation	Nonimaging Nuclear Medicine Probe
Y	Body Part	Central Nervous System

When to Use

Use a code from this group when a nonimaging nuclear medicine probe study is performed on the central nervous system with an other radionuclide to evaluate tracer distribution or physiologic activity. Do not use these codes for imaging studies or for procedures targeting body systems other than the central nervous system.

ICD-10-PCS Codes

1 rows

ICD-10-PCS Code	Description
C05YYZZ	Nonimaging Nuclear Medicine Probe of Central Nervous System using Other Radionuclide

Typical Clinical Scenarios

An elderly patient hospitalized after a fall develops new-onset confusion and fluctuating levels of consciousness; metabolic and structural imaging are inconclusive and clinicians suspect altered cerebral perfusion or tracer distribution related to neurodegenerative or vascular processes. A nonimaging nuclear medicine probe study is performed at the bedside to assess central nervous system tracer uptake and distribution to help differentiate causes of acute encephalopathy. Typical codes: C05YYZZ
A middle-aged patient admitted electively for evaluation of refractory seizures being considered for neurosurgical intervention; prior EEG and MRI provide limited localization of seizure focus. A targeted nonimaging nuclear medicine probe study is used preoperatively to measure radionuclide tracer distribution in the central nervous system to support functional localization prior to definitive treatment planning. Typical codes: C05YYZZ
A hospitalized patient with known brain tumor is being monitored after radiosurgery; clinicians are concerned about treatment effect versus recurrent tumor as the cause of new neurologic deficits. A nonimaging nuclear medicine probe procedure is performed to evaluate changes in central nervous system tracer distribution and physiologic activity to aid inpatient management decisions. Typical codes: C05YYZZ

Related Codes

C050-BRAIN-NONIMAGING-PROBE

ICD-10-PCS Code For Brain: Procedure Code Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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When to Use

ICD-10-PCS Codes

1 rows

ICD-10-PCS Code	Description
C05YYZZ	Nonimaging Nuclear Medicine Probe of Central Nervous System using Other Radionuclide

Typical Clinical Scenarios

An elderly patient hospitalized after a fall develops new-onset confusion and fluctuating levels of consciousness; metabolic and structural imaging are inconclusive and clinicians suspect altered cerebral perfusion or tracer distribution related to neurodegenerative or vascular processes. A nonimaging nuclear medicine probe study is performed at the bedside to assess central nervous system tracer uptake and distribution to help differentiate causes of acute encephalopathy. Typical codes: C05YYZZ
A middle-aged patient admitted electively for evaluation of refractory seizures being considered for neurosurgical intervention; prior EEG and MRI provide limited localization of seizure focus. A targeted nonimaging nuclear medicine probe study is used preoperatively to measure radionuclide tracer distribution in the central nervous system to support functional localization prior to definitive treatment planning. Typical codes: C05YYZZ
A hospitalized patient with known brain tumor is being monitored after radiosurgery; clinicians are concerned about treatment effect versus recurrent tumor as the cause of new neurologic deficits. A nonimaging nuclear medicine probe procedure is performed to evaluate changes in central nervous system tracer distribution and physiologic activity to aid inpatient management decisions. Typical codes: C05YYZZ

Related Codes

C050-BRAIN-NONIMAGING-PROBE

ICD-10-PCS Code For Brain: Procedure Code Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

ICD-10-PCS Code For Central Nervous System: Procedure Code Group Overview

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Central Nervous System Nonimaging Nuclear Medicine Probe Procedure Overview

Code Attributes

ICD-10-PCS Code For Central Nervous System: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Central Nervous System: Procedure Code Group Overview policy alerts

Central Nervous System Nonimaging Nuclear Medicine Probe Procedure Overview

Code Attributes

When to Use

ICD-10-PCS Codes

Typical Clinical Scenarios

Related Codes

What procedures are included in ICD-10-PCS code group C05Y?

How is `C05YYZZ` described in this procedure group?

In what clinical setting is ICD-10-PCS C05Y used for documentation?

Why is accurate coding within the C05Y group important for hospitals?

What are the code attributes associated with this procedure group?

References

When to Use

ICD-10-PCS Codes

Typical Clinical Scenarios

Related Codes

What procedures are included in ICD-10-PCS code group C05Y?

How is `C05YYZZ` described in this procedure group?

In what clinical setting is ICD-10-PCS C05Y used for documentation?

Why is accurate coding within the C05Y group important for hospitals?

What are the code attributes associated with this procedure group?

References