ICD-10-PCS Code For Circulatory: Procedure Code Group Overview

The International Classification of Diseases, Tenth Revision, Procedure Coding System (ICD-10-PCS) code group 6A65 includes procedures performed to treat blood or blood components in the circulatory system using extracorporeal phototherapy. These ICD-10-PCS codes are used for inpatient documentation when a patient requires extracorporeal light-based treatment of circulating blood for therapeutic purposes. Accurate coding within the ICD-10-PCS 6A65 group is essential for proper inpatient reimbursement, as it captures the specific procedure performed and supports clinical documentation accuracy.

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Circulatory Phototherapy Procedure Overview

This procedure group covers extracorporeal phototherapy treatments performed on the circulatory system, where blood or blood components are exposed to light outside the body and then returned to the patient. These procedures target physiological systems and are used to modify circulating elements for therapeutic effect. Accurate ICD-10-PCS coding of these interventions supports appropriate inpatient reimbursement by capturing the specific operation and anatomical focus.

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
6	Section	Extracorporeal or Systemic Therapies
A	Body System	Physiological Systems
6	Operation	Phototherapy
5	Body Part	Circulatory

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ICD-10-PCS Code For Circulatory: Procedure Code Group Overview

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Circulatory Phototherapy Procedure Overview

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
6	Section	Extracorporeal or Systemic Therapies
A	Body System	Physiological Systems
6	Operation	Phototherapy
5	Body Part	Circulatory

When to Use

Use a code from this group when extracorporeal light-based treatment is applied to a patient’s circulating blood or blood components as part of an inpatient therapeutic intervention. These codes are applicable when documentation shows removal of blood, exposure to light, and reinfusion as the intended operative steps.

ICD-10-PCS Codes

2 rows

ICD-10-PCS Code	Description
6A650ZZ	Phototherapy, Circulatory, Single
6A651ZZ	Phototherapy, Circulatory, Multiple

Typical Clinical Scenarios

An adult patient with severe, refractory cutaneous T‑cell lymphoma admitted for escalation of therapy after inadequate response to topical and systemic agents; inpatient extracorporeal phototherapy is performed to treat malignant T‑cells circulating in the blood by removing blood, exposing it to therapeutic light, and returning it to the patient to reduce tumor burden and systemic symptoms. Typical codes: 6A650ZZ, 6A651ZZ
A neonate in the NICU with severe hemolytic disease of the newborn and high bilirubin levels unresponsive to intensive conventional phototherapy and exchange transfusion consideration; extracorporeal phototherapy is used in an urgent inpatient setting to directly treat circulating bilirubin-bearing blood components to lower systemic bilirubin and avoid neurologic injury. Typical codes: 6A650ZZ
A hospitalized patient with chronic graft‑versus‑host disease involving skin and blood after hematopoietic stem cell transplant who undergoes scheduled inpatient extracorporeal phototherapy after outpatient treatments were insufficient; the procedure is performed as a planned inpatient therapeutic session to modulate circulating immune cells. Typical codes: 6A651ZZ

Related Codes

6A60-SKIN-PHOTOTHERAPY

ICD-10-PCS Code For Skin: Procedure Code Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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When to Use

ICD-10-PCS Codes

2 rows

ICD-10-PCS Code	Description
6A650ZZ	Phototherapy, Circulatory, Single
6A651ZZ	Phototherapy, Circulatory, Multiple

Typical Clinical Scenarios

An adult patient with severe, refractory cutaneous T‑cell lymphoma admitted for escalation of therapy after inadequate response to topical and systemic agents; inpatient extracorporeal phototherapy is performed to treat malignant T‑cells circulating in the blood by removing blood, exposing it to therapeutic light, and returning it to the patient to reduce tumor burden and systemic symptoms. Typical codes: 6A650ZZ, 6A651ZZ
A neonate in the NICU with severe hemolytic disease of the newborn and high bilirubin levels unresponsive to intensive conventional phototherapy and exchange transfusion consideration; extracorporeal phototherapy is used in an urgent inpatient setting to directly treat circulating bilirubin-bearing blood components to lower systemic bilirubin and avoid neurologic injury. Typical codes: 6A650ZZ
A hospitalized patient with chronic graft‑versus‑host disease involving skin and blood after hematopoietic stem cell transplant who undergoes scheduled inpatient extracorporeal phototherapy after outpatient treatments were insufficient; the procedure is performed as a planned inpatient therapeutic session to modulate circulating immune cells. Typical codes: 6A651ZZ

Related Codes

6A60-SKIN-PHOTOTHERAPY

ICD-10-PCS Code For Skin: Procedure Code Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

ICD-10-PCS Code For Circulatory: Procedure Code Group Overview

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Circulatory Phototherapy Procedure Overview

Code Attributes

ICD-10-PCS Code For Circulatory: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Circulatory: Procedure Code Group Overview policy alerts

Circulatory Phototherapy Procedure Overview

Code Attributes

When to Use

ICD-10-PCS Codes

Typical Clinical Scenarios

Related Codes

What procedures are included in ICD-10-PCS code group 6A65?

What are the specific ICD-10-PCS codes in this group?

Under which ICD-10-PCS section and body system do these codes fall?

Why is accurate coding within the 6A65 group important for inpatient care?

What clinical setting uses these ICD-10-PCS codes?

References

When to Use

ICD-10-PCS Codes

Typical Clinical Scenarios

Related Codes

What procedures are included in ICD-10-PCS code group 6A65?

What are the specific ICD-10-PCS codes in this group?

Under which ICD-10-PCS section and body system do these codes fall?

Why is accurate coding within the 6A65 group important for inpatient care?

What clinical setting uses these ICD-10-PCS codes?

References