2026 Formulary (Drug List) — Pharmacy Coverage Criteria
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Governs the HealthPartners pharmacy drug list (formulary) effective January 1, 2026; informs members and providers about covered medicines, tiers, specialty designations, limits, and prior authorization/step-therapy programs.
No material clinical or coverage changes in this revision.
Coverage Criteria
Quantity Limit Review Criteria
Coverage decisions and overrides
Supports prior authorization review
Step Therapy Coverage
Step therapy coverage logic
Approval needed if prior steps not met
Formulary administrative criteria
Coverage and administrative requirements as listed for products in this section
Administrative flags reflect coverage pathways; no clinical medical necessity criteria are provided in these chunks.
Coverage stance by formulary entry
Formulary coverage and requirements as listed per product entry
Reflects product-level coverage stance as listed in the formulary table.
Failure to obtain required Prior Authorization (PA) may result in a prescription not being covered under the HealthPartners pharmacy benefit. Drugs that are flagged with PA in the formulary must have prior approval from the payer before coverage will be provided.
Within the provided formulary excerpts there are no explicit medical exclusions stated. Product rows show administrative flags such as PA, QL and ACA, but the text in these chunks does not list medicines as specifically excluded for medical reasons.
The excerpted lines do not present explicit exclusion statements. Entries list device and product coverage annotations (for example ACA, QL, PA) but do not identify any products as expressly excluded from coverage for clinical or medical-necessity reasons.
This section only shows product-level requirement and limit codes (e.g., PA, QL) for ophthalmic and related entries. There are no explicit exclusion rules stated in the provided lines — only the per-product requirement/limit annotations are shown.
Within the supplied extract there are no statements identifying items as 'not medically necessary'. The lines include requirement flags and tiering but do not contain explicit 'not medically necessary' determinations.
Formulary Listings and Coding Examples
| NOXAFIL ORAL SUSP,DELAYED RELEASE FOR RECON 300 MG | listed with Drug Tier = 3, Requirements Limits = PA |
| nystatin oral suspension 100,000 unit/ml | listed with Drug Tier = 3, Requirements Limits = QL (480 per 30 days) |
| posaconazole oral suspension 200 mg/5 ml (40 mg/ml) | listed with Drug Tier = 3, Requirements Limits = PA |
| voriconazole oral tablet 200 mg, 50 mg | listed with Drug Tier = 3, Requirements Limits = PA |
| abacavir oral tablet 300 mg | listed with Drug Tier = 3, Requirements Limits = . |
| acyclovir oral tablet 400 mg, 800 mg | listed with Drug Tier = 3, Requirements Limits = . |
| nystatin oral suspension 100,000 unit/ml | Listed with Drug Tier = 3; QL (480 per 30 days) |
| posaconazole oral suspension 200 mg/5 ml (40 mg/ml) | Drug Tier = 3; Requirements Limits = PA |
| voriconazole oral tablet 200 mg, 50 mg | Drug Tier = 3; Requirements Limits = PA |
| abacavir oral solution 20 mg/ml | Drug Tier = 3 |
| BIKTARVY ORAL TABLET 30-120-15 MG | Drug Tier = 3 |
| EPCLUSA ORAL TABLET 200-50 MG | Requirements Limits = PA; S |
| HARVONI ORAL TABLET 45-200 MG | Requirements Limits = PA; S |
| LEDIPASVIR-SOFOSBUVIR ORAL TABLET 90-400 MG | Drug Tier = 6; Requirements Limits = PA; S |
| MAVYRET ORAL TABLET 100-40 MG | Drug Tier = 6; Requirements Limits = PA; S |
| oseltamivir oral capsule 30 mg | Drug Tier = 3; QL (20 per 30 days) |
| oseltamivir oral capsule 45 mg, 75 mg | Drug Tier = 3; QL (10 per 30 days) |
| PAXLOVID ORAL TABLETS, DOSE PACK 150 | Drug Tier = 3; QL (4 per 1 day) |
| PAXLOVID ORAL TABLETS, DOSE PACK 300 MG | Drug Tier = 3; QL (6 per 1 day) |
| ALINIA ORAL SUSPENSION FOR RECONSTITUTION 100 MG/5 ML | Drug Tier = 4; Requirements Limits = PA; QL (180 per 30 days) |
| linezolid oral tablet 600 mg | Drug Tier = 3; Requirements Limits = QL (2 per 1 day) |
| XIFAXAN ORAL TABLET 200 MG, 550 MG | Drug Tier = 3; Requirements Limits = PA |
| amoxicillin oral suspension for reconstitution 125 mg/5 ml | Drug Tier = 3 |
| amoxicillin oral tablet 500 mg | Drug Tier = 3 |
| amoxicillin-pot clavulanate oral tablet 250-125 mg | Drug Tier = 3 |
| ampicillin oral capsule 500 mg | Drug Tier = 3 |
| dicloxacillin oral capsule 250 mg | Drug Tier = 3 |
| ciprofloxacin hcl oral tablet 250 mg | Drug Tier = 3 |
| levofloxacin oral tablet 250 mg | Drug Tier = 3 |
| moxifloxacin oral tablet 400 mg | Drug Tier = 3 |
| sulfadiazine oral tablet 500 mg | Drug Tier = 4; Requirements Limits = PA |
| sulfamethoxazole-trimethoprim oral tablet 400-80 mg | Drug Tier = 3 |
| abiraterone oral tablet 250 mg | Requirements Limits = PA; ONC; TD; S |
| anastrozole oral tablet | Drug Tier = 7; Requirements Limits = ONC |
| capecitabine oral tablet 150 mg | Requirements Limits = ONC; S |
| dasatinib oral tablet 100 mg | Requirements Limits = PA; ONC; TD; S |
| everolimus (antineoplastic) oral tablet 10 mg | Requirements Limits = PA; ONC; TD; S; QL (1 per 1 day) |
| ROZLYTREK ORAL CAPSULE 100 MG | Requirements Limits = PA; ONC; TD; S; QL |
| TAGRISSO ORAL TABLET 40 MG | Drug Tier = 7; Requirements Limits = PA; ONC; TD; S; QL (1 per 1 day) |
| TAFINLAR ORAL CAPSULE 50 MG | Requirements Limits = PA; ONC; S |
| N/A | No explicit CPT/HCPCS/ICD-10/NDC codes present in these chunks; only product names, formulations, and tiers are listed. |
| XELJANZ XR 11 MG, 22 MG | XELJANZ XR ORAL TABLET EXTENDED RELEASE 24 HR |
| BIJUVA | BIJUVA ORAL CAPSULE 0.5-100 MG, 1-100 MG |
| DUAVEE | DUAVEE ORAL TABLET 0.45-20 MG |
| MYFEMBREE | MYFEMBREE ORAL TABLET 40-1-0.5 MG |
| ORIAHNN | ORIAHNN ORAL CAPSULE, SEQUENTIAL 300-1-0.5MG(AM) /300 MG(PM) |
| OSPHENA | OSPHENA ORAL TABLET 60 MG |
| ANNOVERA | ANNOVERA VAGINAL RING 0.15-0.013 MG/24 HOUR |
| TWIRLA | TWIRLA TRANSDERMAL PATCH WEEKLY 120-30 MCG/24 HR |
| VCF | VCF CONTRACEPTIVE FILM VAGINAL FILM 28 % |
| QL (3 per 30 days) | Quantity limit for certain oral contraceptives (3 per 30 days) |
| Drug Tier = 3 | Tier assignment for listed oral contraceptives |
| Requirements Limits = ACA | Coverage requirement/limit code (ACA) |
| PA | Prior authorization required (appears for several ophthalmic agents) |
| QL (5 per 30 days) | Quantity limit for CYSTADROPS |
| QL (15 per 30 days) | Quantity limit for CYSTARAN |
| S | Specialty or site restriction |
| Drug Tier = 4 | Tier assignment for some ophthalmic products (e.g., LEVOFLOXACIN 0.5% listed as Tier 4) |
Provider Actions and Authorization Requirements
Prior Authorization Required — Flagged Products
Certain medicines listed in the drug table are designated with requirement flags (for example: PA, S, ST, QL, ONC, ACA). When a product is marked PA (Prior Authorization) the prescriber or member must obtain prior authorization from HealthPartners before the drug will be covered under the pharmacy benefit. Failure to secure required PA may result in claim denial or non‑coverage.
- PA indicates Prior Authorization is required before coverage.
- S indicates specialty routing or specialty program requirements.
- ST indicates Step Therapy — preferred alternatives must be tried first.
- QL indicates a Quantity Limit — requests above the listed amount will be reviewed.
Prior Authorization Required for Many Agents
Many specialty, oncology, injectable, and select oral agents in the formulary are subject to prior authorization. Examples include oral oncology agents, biologics, palforzia allergy products, select antiviral and specialty antiviral agents, and many GLP‑1 / diabetes agents (liraglutide, semaglutide products, tirzepatide, etc.). For these products the Requirements Limits field will include PA, often together with S (specialty) and/or QL.
- Specialty and oncology agents commonly show PA; some also require specialty routing (S) and have quantity limits (QL).
- Selected antiviral regimens and hepatitis C agents include PA and may also include S.
- Selected GLP‑1 and other diabetes agents are listed with Requirements Limits = PA and may have QLs.
Documentation and Quantity‑Limit Overrides
Prescribers must submit supporting documentation with PA requests and for any requests that exceed a product’s quantity limit. Documentation should demonstrate medical necessity and include diagnosis, prior therapies tried (including dates and outcomes), relevant lab or clinical data, and rationale for the requested quantity or agent.
- Requests above a QL are reviewed for medical necessity and require documentation of diagnosis and alternatives tried.
- Program‑specific flags (ONC, TD, S, QL) require corresponding documentation per HealthPartners procedures.
- When a product is flagged PA or S, include clinical rationale and any specialty pharmacy routing details in the submission.
Denial Risk — PA and Quantity Limits
PA and QL flags on the drug list are operational triggers — claims submitted for products marked PA without an approved authorization or for quantities exceeding the listed QL are at risk of denial at point of adjudication. Providers should verify authorization status before dispensing and follow HealthPartners’ PA submission process.
- Claims for PA‑listed drugs may be denied if an authorization is not in place.
- Claims exceeding QL will be subject to review and may be denied without adequate supporting documentation.
- Specialty program flags (S) and step‑therapy flags (ST) can also trigger coverage edits or channeling to a specialty pharmacy.
Step Therapy and Specialty Program Indicators
Step therapy and specialty program indicators appear on some entries. ST indicates a step‑therapy requirement (for example, certain PCSK9/REPATHA entries), and S indicates specialty pharmacy routing or program participation. Where step therapy applies, members must have trialed required alternatives or obtain an exception/approval.
- ST = Step Therapy; patient must try specified preferred medicines first or obtain approval.
- S = Specialty program or specialty pharmacy routing required.
- If step therapy or specialty routing is listed, include prior treatment history and rationale when requesting PA.
Definitions and Abbreviations
Initial Therapy Criteria
Step Therapy Rules
| Step therapy statement | Notes / implication |
|---|---|
| Try specified preferred medicines first | |
| A medicine with step therapy will be covered only if the member has already tried required prior medicine(s); if not, prior approval from HealthPartners is required before coverage at the lower cost-share. |
| Step therapy / specialty flag | Examples / implication |
|---|---|
| 'S' indicator present on some hepatitis C agents | |
| Examples include LEDIPASVIR‑SOFOSBUVIR and MAVYRET which are listed with Requirements Limits = PA; S, indicating specialty/step program requirements before coverage. |
| Flag(s) | Interpretation / example agents |
|---|---|
| 'TD' and 'S' flags on oncology/specialty agents | |
| Antineoplastic entries (e.g., abiraterone, everolimus) include PA; ONC; TD; S — indicating specialty distribution or program enrollment may be required as part of access prior to coverage. |
| Flag | Coverage implication / examples |
|---|---|
| 'TD' or 'ONC' flags for oncology agents | |
| Targeted cancer therapies (ROZLYTREK, TAGRISSO) and other oncology drugs show ONC or TD flags; these denote oncology benefit/specialty handling and may require specialty routing or program steps before coverage. |
| Designation | Meaning / examples |
|---|---|
| 'S' designation on products | |
| Several products (for example AUSTEDO, EVRYSDI) carry 'S' indicating step therapy or specialty clinical edit applies and must be followed per formulary requirements. |
| Observation | Implication |
|---|---|
| No explicit step sequences listed in some sections | |
| Portions of the formulary list products with PA, QL, and Tier designations but do not provide step-by-step therapy algorithms; utilization management is implemented via PA, QL, and tiering where present. |
| Step therapy flag | Example / note |
|---|---|
| 'ST' indicated for some agents | |
| REPATHA SureClick and syringe entries are labeled ST; QL (0.071 per 1 day), indicating step therapy (ST) is required before coverage at the listed benefit level. |
| 'S' specialty/step marker | Examples |
|---|---|
| 'S' required for certain specialty oral agents | |
| Examples include carglumic acid and deferasirox which are listed with Requirements Limits = PA; S, indicating specialty program or step requirements and that PA/submission is required. |
| PA noted | Examples (GLP‑1 / diabetes agents) |
|---|---|
| Prior authorization indicated for several GLP‑1 / diabetes agents | |
| MOUNJARO, liraglutide and OZEMPIC entries are shown with Requirements Limits = PA and have numeric QL values (e.g., liraglutide QL 0.3 per 1 day), indicating PA applies for these agents. |
| Coverage annotation | Implication / examples |
|---|---|
| 'ACA' or 'S' on vaccines and biologics | |
| Some vaccines and biologics are annotated ACA (Affordable Care Act preventive coverage) or S (specialty); examples include AREXVY and PALFORZIA levels which show ACA or PA; S markings implying special coverage pathways or program requirements. |
| Observation | Interpretation |
|---|---|
| Step therapy often implied rather than explicit | |
| In many formulary sections step therapy is implied by tiering and presence of PA/S/QL flags; explicit step-by-step sequences are not present within the extracted chunks. |
Quantity Limits (Selected Items)
Site of Care and Specialty Pharmacy Routing
Fill specialty medicines at specialty pharmacy when required
Certain specialty medicines and oncology drugs must be filled at a specialty pharmacy; prescribers should route prescriptions to the specialty pharmacy as indicated by the formulary.
Follow 'S' specialty/site routing for ophthalmic products
Some ophthalmic products include a specialty/site 'S' designation and may require specialty routing or site‑specific handling; follow the 'S' designation when submitting and routing prescriptions.
Background
The formulary groups medicines by therapeutic category and assigns cost-sharing tiers (Tier 1–7) to determine member out-of-pocket responsibility. Specialty medicines — typically high-cost products for chronic or complex conditions — are identified and commonly managed through specialty pharmacy channels and different benefit rules. The table uses requirement codes (for example PA = prior authorization; QL = quantity limit; ACA = Affordable Care Act preventive designation; S = specialty or step/program indicator) to convey administrative coverage requirements that affect how and when a specialty medicine will be covered.
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