Medical Necessity Guidelines: Experimental, Investigational or Unproven Services
Customize your policy alerts
Sign up for EmblemHealth Policy MG.MM.AD.11 alerts
Get alerted when Policy MG.MM.AD.11 changes without checking for updates manually.
Monitor payer policy activity
Defines EmblemHealth's criteria for labeling devices, treatments, procedures, drugs, or supplies as investigational/experimental/unproven and restricts coverage accordingly for affected members and providers.
Added New Codes effective 7/01/2026 for Commercial and Medicare including multiple U, T, and Q codes (e.g., 0631U–0659U, 1026T–1053T, A9294, G0685).
Removed Deleted Codes effective 7/01/2026 including 0029U, 0031U, 0577U and Commercial 0423U.
Added multiple new codes effective 1/01/2026 and 4/01/2026 across Commercial and Medicare (large lists of U/T/Q/C codes).
Multiple CPT/HCPCS/proprietary codes were added for Commercial and Medicare in the July 13, 2024 revision.
Multiple code additions and removals were recorded across several dates (2022-2024) including bulk additions effective 1/1/2023 and other periodic updates.
Coverage Criteria — Investigational / Experimental / Unproven
Investigational / Experimental / Unproven — Not Medically Necessary
Service is considered investigational/experimental/unproven and not medically necessary if ANY of the following are met:
Evidence hierarchy used: (1) technology assessments/meta‑analyses; (2) well‑designed randomized studies; (3) high‑quality case‑control or cohort studies; (4) historical control studies; (5) expert opinion.
Not Medically Necessary / Experimental Code Listings
Codes designated experimental, investigational or noncovered
This section contains mapping and revision history entries (code lists and status changes) rather than clinical AND/OR decision logic.
EmblemHealth considers the quality and type of evidence when determining whether a service is investigational, experimental, or unproven. Reports that do not contain scientifically valid data—such as abstracts, anecdotal accounts, or personal professional opinions—are not considered reliable evidence and should not be used to support coverage. Only published reports and articles with scientifically valid data in peer‑reviewed medical and scientific literature are acceptable as evidence for coverage determinations.
The document sections cited here are composed of code mapping rows and lists specifically applicable to Commercial Plans. These chunks present CPT/HCPCS code equivalencies and crosswalks (example: 0311U, 0134U = 0317U) intended to guide coding and adjudication for Commercial products rather than to state clinical coverage criteria.
Content in these chunks is limited to code crosswalks and mappings for billing purposes. They contain grouped CPT/HCPCS pairings and examples (for example, grouped mappings such as 11950 series and multi‑code crosswalk rows) and do not provide additional clinical decision logic.
Codes labeled in this document as "Experimental & Noncovered Investigational by CPT Code (Medicare Plans)" are treated as experimental or noncovered in the mappings shown. When a CPT code is flagged with this designation it is mapped to alternate HCPCS/Q codes in the tables and may be treated as noncovered for the referenced plan type.
The Limitations/Exclusions section was updated to include hyperlinks to related Clinical Trial Medical Policies; providers and reviewers should use those linked Clinical Trial policies for additional guidance where indicated in this section.
Codes shown as removed in the revision history entries should no longer be treated as part of the active code lists for coverage determinations. Revision history rows list codes added and removed on specific dates; any code recorded as "removed" in those entries is excluded from the current Experimental/Investigational code lists.
The revision history entries explicitly identify codes such as 88360 and 0500T under 'Codes removed' and/or with coverage notes (e.g., 'Covered for Commercial' or 'Covered for preventive services'). Those entries indicate these codes were removed from the experimental/unproven listings or had their coverage designation changed in the revision history.
Revision history documents that certain Commercial codes (for example, 88360 and 0500T) were removed from the Experimental/Investigational lists and that their Commercial coverage status changed. These code‑level removals are recorded as explicit exclusions from the experimental code lists for Commercial lines.
The revision history identifies numerous codes that were removed from or reclassified within the experimental/unproven lists. These entries document coding status changes (additions, removals, coverage reversals) and should be used to update operational code tables rather than to establish new clinical necessity criteria.
This portion of the document is limited to revision history entries and enumerated code lists; it does not contain explicit clinical decision logic (AND/OR criteria) for medical necessity—rather, it records coding status changes and crosswalks.
Per the revision history, Commercial coverage for codes recorded as removed (for example, 88360 and 0500T) is excluded from the experimental/unproven code lists. The entries indicate these codes were removed from the experimental designation and their coverage status for Commercial products was changed accordingly.
The Medicaid table was removed from this section of the policy and should not be used for coverage determinations. Revision history entries explicitly state that the Medicaid‑specific table was removed; Medicaid guidance is therefore no longer present in these chunks.
Multiple revision history entries repeat that the Medicaid table has been removed from the policy document; operational teams should not reference the deleted Medicaid table when making coverage determinations.
The policy text repeatedly notes removal of the Medicaid table in the revision history. This explicit removal means Medicaid‑specific coding guidance previously present in the table is no longer applicable within this policy section.
The policy states that any procedure, device, or service that meets any of the investigational criteria is considered not medically necessary. The document includes numerous CPT/HCPCS codes designated investigational for Commercial plans; services billed under those codes may be denied as not medically necessary when they meet the investigational criteria.
Services billed under codes designated as Experimental & Noncovered Investigational in the Medicare mapping tables may be treated as noncovered or denied when mapped to listed HCPCS/Q codes. These mappings communicate the operational noncoverage designation for the referenced plan types.
Specific codes listed in the tables are identified as experimental and noncovered for Medicare and/or Commercial plans. The tables and mapping rows document code status (not covered/experimental) for the listed plan types; use the code lists and revision history to determine current coding status for adjudication.
This section focuses on coding status changes and revision history entries rather than clinical medical necessity logic. It documents which codes were added, removed, or had coverage flags; it does not provide new clinical criteria for determining medical necessity.
Coding — Code Tables and Crosswalks
| 27599 | paired/excluded with many CPT codes in Commercial table (see document) |
| 11951 | listed in combinations in Commercial table |
| 11952 | listed in combinations in Commercial table |
| 43206 | listed as investigational in Commercial table |
| 54240 | listed as investigational in Commercial table |
| 64744 | listed as investigational in Commercial table |
| 76982 | listed as investigational in Commercial table |
| 81231 | listed as investigational in Commercial table |
| 81419 | listed as investigational in Commercial table |
| 81536 | listed as investigational in Commercial table |
| 86153 | listed as investigational in Commercial table |
| 91133 | listed as investigational in Commercial table |
| 96004 | listed as investigational in Commercial table |
| 0353T | present in mapping rows |
| 0130U | present in mapping rows |
| 0358T | mapping result |
| A2011 | example A-code present in mappings |
| C9790 | example C-code present in mappings |
| E0739 | example E-code present in mappings |
| J3490 | grouped code involved in multiple mappings |
| Q4143 | example Q-code present in mappings |
| Q4201, 0941T = Q4202 | crosswalk mapping |
| Q4254, Q4237 = Q4255 | crosswalk grouping/mapping |
| Q4269, Q4239 = Q4279 | crosswalk grouping/mapping |
| Q4308, Q4250 = Q4319 | crosswalk grouping/mapping |
| Q4431, Q4248 = S0800 | crosswalk mapping to S-codes |
| S1090, Q4237 = S2117 | crosswalk mapping |
| S8080, Q4237 = S8130 | crosswalk mapping |
| 11950, 1 = 11951 | example CPT grouping/mapping |
| 53451, 1 = 53452 77615 | example grouped mapping |
| 90868, 1 = 90869 | example grouped mapping |
| 0419T, 0408T = 0420T | temporary-to-permanent T-code mappings |
| 0433T, 0412T = 0439U | mixed T/U mapping |
| 0497T, 0418T = 0506T | T-code mapping |
| 0528T, 0418T = 0535u | T-code mapping |
| 0497T | Listed mapping example |
| 0415T | Listed mapping example |
| 0503U | Mapped code |
| 33548 | Mapped to A2001-A2012 in examples |
| A2013 | Mapped to 0751T etc in examples |
| J7030 | listed as mapping to Q4291 / Q4303 in E&I tables |
| J7040 | listed as mapping to Q4292 / Q4305 / Q4329 / Q4365 etc. |
| J7050 | listed as mapping to Q4293 / Q4306 / Q4330 / Q4366 etc. |
| K1007 | listed as mapping to Q4294 / Q4307 / Q4331 / Q4367 etc. |
| K1016 | listed as mapping to Q4295 / Q4308 / Q4332 / Q4368 etc. |
| K1017 | listed as mapping to Q4296 / Q4309 / Q4333 / Q4369 etc. |
| K1018 | listed as mapping to Q4297 / Q4310 / Q4334 / Q4370 etc. |
| K1019 | listed as mapping to Q4298 / Q4311 / Q4335 / Q4371 etc. |
| K1028 | listed as mapping to Q4299 / Q4312 / Q4336 / Q4372 etc. |
| K1029 | listed as mapping to Q4300 / Q4313 / Q4337 / Q4373 etc. |
| 0631U–0659U | group of new U-codes added effective 7/01/2026 (policy lists individually) |
| 1026T–1053T | group of new T-codes added effective 7/01/2026 (policy lists individually) |
| A9294 | added effective 7/01/2026 |
| G0685 | added effective 7/01/2026 |
| Removed codes lists (examples) | Examples of removed codes across dates: 0029U, 0031U, 0577U, 23700, 23701, 24300, etc. |
Provider Actions — Prior Authorization, Documentation, Billing
Submit clinical evidence with PA
Prior authorization requests must include the clinical evidence that the patient meets the policy criteria; without this documentation EmblemHealth cannot properly review the request and approval may be prevented.
Reference Commercial code crosswalks for PA
Code equivalencies and crosswalks for Commercial Plans are listed in the policy and providers should reference these mappings when requesting prior authorization because mapped codes may affect PA decisions and claim adjudication.
Bill using mapped permanent HCPCS/CPT codes
When temporary procedure codes have been crosswalked to permanent HCPCS/CPT codes (for example 0941T–0951T mappings), providers should bill using the mapped permanent code per the crosswalk when available.
Confirm PA for services mapped to experimental codes
For services mapped to experimental or noncovered codes (specific CPT-to-HCPCS mappings are listed), providers must confirm applicable prior authorization requirements before submission.
Verify PA/coverage for codes added 7/01/2026
A set of new E&I codes was added effective 7/01/2026 (examples include 0631U–0659U, 1026T–1053T, A9294, G0685); these codes will be treated as experimental/noncovered per the policy unless other coverage criteria apply, so verify PA and coverage before billing.
Verify PA when using newly listed codes
Several codes were added to the Experimental/Investigational list for Commercial and Medicare in recent revisions; providers should verify prior authorization requirements for services billed with newly listed codes per payer guidance.
Confirm code-level coverage and PA per product
Multiple codes were added, removed, or had coverage flags in the revision history (e.g., 0357U–0361U, 0738T–0783T, 30469, 22860, 0047U); providers must verify coverage and prior-authorization requirements for the member's product before submission.
Follow plan PA policy for 0047U
Follow the plan's coverage and prior authorization rules for code 0047U, which was added with a Commercial coverage reversal noted in the revision history.
Apply standard Commercial PA process for 0047U
Commercial prior authorization processes apply to code 0047U (Commercial code was added; verify PA implications under Commercial lines before submission).
Verify current authorization/coverage for 0047U
Commercial coverage for 0047U was added then reversed in revision history; providers must verify the current prior authorization requirements and coverage status before submitting claims.
Confirm PA requirements for 0047U given coverage reversal
Commercial code 0047U was added and later had its Commercial coverage status reversed; confirm the code's current coverage and any prior authorization requirements before billing.
Anticipate PA/claim impacts for 0047U status changes
Because 0047U's Commercial coverage status was reversed after being added, prior authorization or claim handling for this code may be affected; verify benefit-specific PA and adjudication rules.
Verify PA for newly added or removed codes
Coding changes in the revision history (additions/removals and coverage status changes) may affect prior authorization requirements for Commercial and Medicare lines; verify benefit-specific prior auth for affected codes before submission.
Verify PA for codes with recent revisions
Revision history shows many codes were added, removed, or had coverage changes; providers must verify prior authorization requirements for these revised codes against current payer systems before submitting claims.
Use established alternatives when available
Policy requires that services be comparable or superior to conventional therapies; if established alternatives exist that are more beneficial, the service may be considered investigational and prior authorization may not be approved.
Treating physician must submit clinical evidence
The treating physician or primary care provider must submit clinical evidence demonstrating the patient meets the policy criteria; EmblemHealth uses peer‑reviewed literature, regulatory status, guidelines and expert opinion to evaluate requests.
Ensure claims use documented HCPCS/CPT crosswalks
Claims should reflect the specific HCPCS/CPT crosswalks documented in the policy (use the alphanumeric mappings to A-, C-, E-, J-, Q-codes as shown) so payer mapping guidance is matched on the claim.
Align claim coding with CPT→HCPCS/A mappings
Claims must reflect correct CPT‑to‑HCPCS/A‑code mappings as shown in the policy; mismatches between billed codes and the documented mappings may affect adjudication and trigger review.
Reference policy code lists when submitting claims
Providers should reference the policy's code lists when submitting claims to avoid billing codes identified as experimental, investigational or noncovered; the policy contains extensive code lists and crosswalks to guide coding.
Verify billed codes against current code list
Ensure billed codes reflect the current policy revision lists; many codes were added or removed on specific revision dates and billing with outdated codes may result in coverage issues.
Use revision history coverage flags when filing claims
Revision history documents code‑level coverage flags (for example, 0047U is marked 'Covered for Medicare'); reference these entries when filing claims to support coverage determinations.
Reference current coding table for claims
Providers should reference the current policy coding table and revision history when submitting claims, since revision entries document code status changes that affect coverage and adjudication.
Include revision history when submitting claims
Revision entries document code status changes and should be referenced when submitting claims to ensure correct coding and support coverage determinations.
Document code revisions with claims
Reference the current code list documented in the revision history when submitting claims; the history records code‑level coverage status and changes that are relevant to claims processing.
Do not use removed Medicaid table for claims
The Medicaid-specific table was removed from this policy and should not be referenced for Medicaid coverage determinations or included in claim documentation.
Document effective dates for added codes
Revision entries list an effective date (for example 2/15/2023) for a large set of added codes; include the effective date in documentation when submitting claims for those codes.
Reference updated code lists in documentation
Revision history documents code additions, removals, and coverage reversals; providers should reference updated code lists when submitting claims to reflect the current status of each code.
Omission of clinical evidence may cause PA denial
Failure to submit the required clinical evidence that a patient meets the policy criteria will prevent EmblemHealth from properly reviewing a prior authorization request and can lead to denial.
Claims using mapped codes may be subject to E&I review
Claims submitted using codes listed in the policy's mapping tables may be subject to Experimental/Investigational coverage determination and could be denied if mappings indicate noncoverage.
Incorrect or missing code mappings risk denial
Claims that use codes not present in the crosswalks or that pair codes incorrectly with mapped results may be denied due to non-matching code mappings shown in the policy.
E&I Medicare mappings can trigger noncoverage under Commercial plans
Use of codes identified as 'Experimental & Noncovered Investigational' (Medicare mappings shown) may trigger noncoverage or denial when billed under Commercial plans if mapped to listed HCPCS/Q-codes.
Denial risk for billing E&I-designated codes
Billing for codes designated as Experimental & Noncovered Investigational (examples include many Q/J/K/S/V mappings) may trigger noncoverage or denial when submitted under Medicare or Commercial plans.
Risk of denial for claims with removed codes
Claims using codes listed as removed in revision history may be denied if those codes are no longer recognized under the Experimental/Investigational listings recorded in the policy.
Claims with removed codes (e.g., 88360, 0500T) may not be paid
Claims submitted with codes that were removed (for example 88360 and 0500T) may not be paid under the coverage referenced in the revision history; verify current status before billing.
Removed Commercial codes may be denied or reprocessed
Claims billed with Commercial codes removed from coverage (for example 88360, 0500T) may be denied or require reprocessing if those codes are no longer covered.
Denial risk when using reclassified/removed codes
If codes were removed from the experimental/unproven list and reclassified (for example 88360, 0500T), submitting claims inconsistent with the updated coverage status may trigger denial.
Verify status for codes removed from E&I listing
Codes removed from the experimental/investigational listing (for example 88360 removed and marked 'Covered for Commercial') may be processed differently and incorrect use could trigger coverage denials; verify current status per revision history.
Potential denial for removed or changed codes
Claims billed with codes that were removed, moved, or had coverage changes (for example 88360, 0500T) may be denied or require adjustment per the revision history; confirm current coverage before submission.
Background
Background: EmblemHealth restricts coverage to services with proven safety and efficacy. A service is considered investigational/experimental/unproven if it lacks final regulatory approval, has insufficient or inconclusive peer‑reviewed evidence, is less beneficial than established alternatives, or otherwise does not meet the Plan's evidence thresholds. The policy defines reliable evidence and excludes anecdotal reports or abstracts from consideration.
Definitions
Revision History — Code Additions, Removals, and Status Changes
New U-, T-, and other codes (e.g., 0631U–0659U, 1026T–1053T, A9294, G0685) were added effective 07/01/2026 for Commercial and Medicare.
Multiple new Commercial codes were added effective 01/01/2026 (examples listed in the revision history: 0600U–0613U, 0988T–1024T and numerous Q-codes).
New codes effective 04/01/2026 were added for Commercial and Medicare including U-codes (0614U–0630U) and Commercial-only A- and Q-code entries.
Added new codes effective 07/01/2026 including U-code range 0631U–0659U and T-code range 1026T–1053T (also A9294, G0685) for Commercial and Medicare.
Added multiple new Commercial and Medicare codes effective 01/01/2026 (examples: 0600U–0613U, 0988T–1024T and many Q-codes).
Batch additions effective 01/01/2023 included temporary and T-code groups such as 0357U–0361U and many 07xxT series (documented in the revision history).
Removed/deleted codes effective 07/01/2026 include 0029U, 0031U, 0577U (Commercial and Medicare) and Commercial 0423U.
Removed/deleted codes effective 01/01/2026 list multiple items for Commercial and Medicare (examples in revision entries).
Large sets of temporary/T-codes were recorded as added or removed around the 01/01/2023 batch revisions; revision history documents removals in that timeframe.
Batch additions effective 01/01/2023 included codes 0357U–0361U and a large series of T-codes (0738T–0783T and subsets) for Commercial and Medicare.
Revision entries reference codes that were later listed with effective dates tied to 02/15/2023 additions (many 0746T–0783T entries documented in later history).
Codes added that became effective 01/01/2023 are documented (examples include 0357U–0361U and many 07xxT series).
Multiple HCPCS/CPT codes listed in revision history (e.g., 0357U–0361U, 0738T–0741T and 0047U) were recorded as added or otherwise changed across revisions.
Revision entry documents codes removed effective 10/01/2026 (entries enumerate affected Commercial and Medicare codes).
A set of T-codes (0746T–0783T and adjacent ranges) were added with effective dates recorded in the revision history and referenced repeatedly across entries.
Revision history documents addition of numerous T-code and CPT entries effective 01/01/2023 and referenced in subsequent updates.
Added T-codes and other codes effective 02/15/2023 (0746T–0783T and many related T-codes) as recorded in the revision history.
Documentation from 12/29/2022 lists codes that were designated to take effect 01/01/2023, including multiple U- and T-code series later referenced with 02/15/2023 effective-notes.
Revision record dated 07/31/2026 documents a correction to the 10/20/2025 revision and other recent changes (entry present in the revision history).
Entries on 06/26/2026 list additions effective 07/01/2026 (U- and T-code groups) and an added code effective 01/01/2027 (22860 for Commercial).
Revision history documents examples of codes added/removed or with coverage changes (e.g., 0047U added/reversed, 88360 and 0500T removed then marked covered in certain lines).
Large enumerations of T-codes added around 02/15/2023 are shown in revision entries; the history also documents codes later removed or reclassified.
Revision entries record notable CPT/HCPCS changes including code 0047U being added for Commercial (coverage reversed) and codes 88360 and 0500T being removed/marked covered in some lines of business.
Multiple T-code additions (0746T–0783T) and related CPT/HCPCS updates are documented with effective dates in the revision history.
A large list of codes was added with effective date 02/15/2023 (numerous T-codes 0746T–0783T and related entries are enumerated in the history).
Revision entries from 06/26/2026 and surrounding dates enumerate a large list of temporary and U/T codes across Commercial and Medicare, many of which are referenced repeatedly in the history.
Revision history spans multiple effective-date groups called out across the document (examples include 07/01/2026, 01/01/2026, 04/01/2026, 02/15/2023 and others).
Most recent revision record dated 07/31/2026 corrects prior entries and references code additions/removals documented earlier in 2026.
OpenPayer is powered by Trek Health's payer performance platform. Trek continuously ingests, validates, and normalizes Transparency in Coverage data alongside payer policies and other commercial payer data to create a structured payer intelligence foundation. OpenPayer uses this foundation to deliver personalized search results, dynamically generated policy pages, and tailored policy monitoring based on each user's payers, specialties, billing codes, and areas of interest. The same intelligence powers broader payer performance workflows, including reimbursement benchmarking, contract evaluation, payer negotiations, and financial decision-making.