Specialty drugs requiring precertification
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List of specialty drugs that require precertification for AmeriHealth Medicare Advantage members, effective January 1, 2026; applies to listed brands, generics, and biosimilars and affects providers submitting precertification requests.
No material clinical or coverage changes in this revision.
Coverage Criteria
The drug list excludes ophthalmological conditions for agents marked with §. Where a drug or class is annotated with §, the exclusion reads: except for ophthalmological conditions.
Therapeutic Categories and Codes
| Flolan | Flolan ® |
| Remodulin | Remodulin ® |
| Revatio | Revatio ® |
| Trevyent | Trevyent* |
| Tyvaso | Tyvaso ® |
| Uptravi IV | Uptravi IV |
| Veletri | Veletri ® |
| Ventavis | Ventavis ® |
| No codes listed |
| Cinqair | Cinqair ® |
| depemokimab | depemokimab* |
| Omlyclo | Omlyclo |
| Synagis | Synagis ® |
| Xolair | Xolair ® |
| No codes listed |
| Aralast | Aralast |
| Glassia | Glassia™ |
| Prolastin | Prolastin ® |
| Zemaira | Zemaira ® |
| No codes listed |
| Amtagvi | Amtagvi™ |
| Imdelltra | Imdelltra™ |
| linvoseltamab | linvoseltamab* |
| Tecelra | Tecelra ® |
| No codes listed |
| Adakveo | Adakveo ® |
| Amvuttra | Amvuttra™ |
| apitegromab | apitegromab* |
| Bkemv | Bkemv™ |
| Cosela | Cosela ® |
| Crysvita | Crysvita |
| deramiocel | deramiocel* |
| Enjaymo | Enjaymo™ |
| Epibbli | Epysqli ® |
| Evkeeza | Evkeeza™ |
| No codes listed |
Provider Actions and Authorization Requirements
Precertification required for listed specialty drugs
As of January 1, 2026, all listed specialty brands and their generic equivalents or biosimilars require precertification for AmeriHealth Medicare Advantage members; the list is subject to change.
- Applies to all brands listed in the document and any generics or biosimilars.
Prior authorization details not specified in this list
This segment lists drug names by therapeutic category and does not provide detailed prior authorization criteria or clinical triggers.
- Providers must follow general precertification process but no PA rules are specified here.
List subject to change; biosimilars and class members require precertification
The list is subject to change; precertification requirements also apply to FDA‑approved biosimilars and to any unlisted brands, generics, or new drugs approved in a listed class during the benefit year.
- Reference-product biosimilars marked with ‡ are included under the biosimilar applicability note.
Drug list only — no extra provider actions in this segment
This excerpt contains only drug listings by category (see respiratory and miscellaneous sections); no additional provider-action instructions are included in chunk 19 beyond the drug names.
- Providers should not infer authorization criteria from the drug list alone.
Precertification review vendor and documentation notes
Drugs marked with † are subject to precertification review by CareCore National, LLC d/b/a eviCore healthcare; benefits, copayments, and restrictions may apply and may change annually.
- Contact the external review vendor for precertification requirements where noted.
- Benefits and cost‑sharing provisions may change on January 1 of each year.
Agent listing only — no additional provider instructions in this section
The miscellaneous therapeutic agents section lists many brands but does not specify additional provider-action steps or documentation requirements in chunk 22 itself.
- Providers must submit precertification requests when applicable, but chunk 22 contains only the agent names.
Denial risk if precertification is not obtained
Failure to obtain precertification for any listed specialty drug, including its generic equivalents or biosimilars, may result in denial or coverage limitation.
- Obtain precertification before initiating therapy to avoid claim denials or coverage actions.
No authorization/denial triggers provided in this list
This segment provides only drug names grouped by category and does not include explicit authorization or denial triggers.
- Do not rely on this list for clinical authorization criteria; seek the full policy or vendor guidance for triggers.
Background
This document is a formulary/precertification listing of specialty drugs that require prior authorization for AmeriHealth Medicare Advantage members effective January 1, 2026. It groups drugs by therapeutic area and specifies that all listed brands, their generic equivalents, and FDA‑approved biosimilars within a class require precertification. Notes indicate certain products are pending approval, subject to external precertification review by CareCore National (eviCore), and that limitations, copayments, and annual benefit changes may apply.
Definitions and Notes
Step Therapy
| Step | Requirement |
|---|---|
| [{"text":"1","status":""},{"text":"No specific step-therapy sequences are provided in this document excerpt; class-level precertification applies to all drugs listed under a therapeutic class ("All drugs that can be classified under this header require precertification"), including unlisted brands, generics, and FDA‑approved biosimilars.","status":""}] |
Site of Care
Site-of-care rules not specified for listed IV agents
Site-of-care requirements (e.g., infusion center rules) are not specified in this portion of the document despite inclusion of intravenous agents.
- If site-of-care rules are needed, consult the full policy or payer/vendor guidance.
Biosimilar Notes
Biosimilar applicability for products marked with ‡
Precertification requirements apply to all FDA‑approved biosimilars to the reference products noted with ‡ in the list (e.g., Soliris ® is marked with ‡).
- When a reference product is marked with ‡, any FDA‑approved biosimilar to that product also requires precertification.
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