AmeriHealth Select Drug Program Formulary and Prior Authorization Procedures
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This document governs the AmeriHealth Select Drug Program formulary structure, safety edits (prior authorization, age/quantity/MME/stimulant limits), and related pharmacy benefit procedures that affect members and providers participating in AmeriHealth plans.
No material clinical or coverage changes in this revision.
Coverage and Safety Edits
General coverage and prior authorization
Covered when ALL of the following are met
Claim dollar limits require PA for claims exceeding $10,000; PA approvals may be time‑limited and without PA the prescription will not be covered at retail or mail order.
Opioid safety edit
Prior authorization required if ANY of the following exceed thresholds
MME is calculated across opioid products per day.
Cumulative stimulant limits
Prior authorization required when cumulative daily stimulant dose exceeds agent-specific limits
Examples include amphetamine 60 mg/day; amphetamine‑dextroamphetamine 60 mg/day; dextroamphetamine 60 mg/day; lisdexamfetamine 70 mg/day; methamphetamine 60 mg/day; dexmethylphenidate 40 mg/day; methylphenidate 72 mg/day; serdexmethylphenidate 52.3 mg/day.
Stimulant cumulative dose coverage
Covered when dispensing does not exceed cumulative stimulant limits; claims exceeding limits require prior authorization
Provider must submit PA via ePA or fax; clinical pharmacists review therapy history and may discuss overrides with prescriber when appropriate.
Coverage stance by drug row
Coverage and administrative requirements vary by drug and are indicated in each row.
Shows tier (NPD), specialty (SP) and PA requirement
Uptravi marked NPD and PA
Dupixent is a preferred brand specialty drug requiring PA
Inclusion of a drug on this formulary does not guarantee coverage for every member. Drug coverage varies by group benefit and some cost-share tiers (including Low-Cost Generic and Specialty) may not be available on all plans. Coverage decisions are based on medical necessity and the member's specific benefit design; providers or members with questions should contact Customer Service using the number on the member ID card. (Formulary is subject to change.)
The formulary is maintained and reviewed by a Pharmacy and Therapeutics Committee of physicians and pharmacists; drugs included were selected for reported medical effectiveness, safety, and value, but inclusion alone does not override plan-specific coverage or utilization management rules.
Tier exception requests are limited by plan design: drugs on the Generic, Preferred Brand, and Specialty tiers are not eligible for tier exceptions. When allowed, requests for tier exceptions require supporting documentation and may require trials of formulary alternatives; completed formulary exception request forms should be faxed to 1-888-671-5285.
Entries flagged as NPD (Non Preferred Drug) indicate that a product is designated non-preferred on the formulary. The document does not list NPD products as categorically excluded; rather, NPD denotes a tiering and potential cost-share difference and may be paired with utilization controls (e.g., PA, QL) on the drug row.
This excerpt does not provide a list of drugs that are explicitly excluded from coverage. Instead, the drug list rows show per-drug tier assignments and utilization controls (PA, QL, AL, etc.); absence from coverage or plan-level exclusions are governed by member benefit documents and are not specified in the provided excerpt.
The document excerpt does not set out formal medical necessity decision algorithms for specific conditions. Rather, coverage decisions are managed through prior authorization and utilization controls where indicated on each drug row; prior authorization is used to confirm medical necessity and appropriateness for those drugs flagged with PA.
No clinical exclusions (for example, blanket clinical contraindications listed as exclusions) are specified in this excerpt. The policy presents per-drug administrative controls (tiering and requirement flags) rather than explicit clinical exclusion statements.
When a prescription falls outside FDA-labeled guidance (for example, an age outside the product's FDA age range), coverage may not be provided unless a Prior Authorization (PA) is obtained documenting medical necessity. Providers may request coverage for off-label or out-of-range use by submitting the PA with supporting clinical rationale.
The excerpt does not contain line-item 'not medically necessary' declarations for specific drugs. General rules indicate that use outside FDA guidance may require prior authorization; explicit not-medically-necessary statements for named products are not included in the provided sections.
Formulary Codes, Limits, and Key Thresholds
| Descovy 200-25mg | HIV PrEP product listed as available at $0 for eligible members |
| Tamoxifen 20mg | Breast cancer chemoprevention product listed as ACA preventive |
| PA | Prior Authorization |
| QL | Quantity Limits Apply |
| LDD | Limited Distribution Drug |
| PB | Preferred Brand |
| SP | Specialty Drug |
| AL | Day Supply/Age Limit |
| NPD | Non Preferred Drug |
| G | Generic |
| LCG | Low Cost Generic |
| R | Requires Rider |
Prior Authorization, Submissions, and Denial Risk
Prior authorization requirements
Prior Authorization Required — AmeriHealth requires prior authorization (PA) for certain prescription drugs to confirm medical necessity, appropriate dosing, and use per FDA‑labeled or medically accepted indications. Clinical pharmacists review PA requests using clinical data, provider‑submitted information, and the member’s prescription history; medical director review may occur if criteria are not met. Without prior authorization, the member’s prescription will not be covered at retail or mail‑order pharmacies. PA approvals may be time‑limited (for example, 6–12 months) and must be renewed when expired. Claim dollar limits trigger PA review for claims exceeding $10,000.
- PA approvals are based on Pharmacy & Therapeutics Committee‑approved criteria and may include review of drug‑drug interactions, contraindications, dosing, therapy duration, and prior therapies.
- PA review may take up to two business days after receipt of complete provider information; incomplete submissions can delay decisions.
- Some drugs require a benefit rider (e.g., certain weight‑loss drugs); contact the health plan for member eligibility and rider details.
Prior authorization required for listed PA drugs
Prior authorization is required for many specific drugs listed on the formulary when the drug’s REQUIREMENTS/LIMITS field includes the notation "PA". This PA requirement applies to all formulations of a listed drug (tablet, capsule, oral suspension, transdermal, injectable, etc.) unless otherwise specified. Claims submitted without the required PA may be denied.
- The drug list shows requirement flags (e.g., PA, QL, Q/T, MME, AL, SP) next to product entries to indicate utilization management controls.
- Providers should check the formulary row for the drug and formulation being prescribed to confirm whether PA applies prior to dispensing.
Authorization/Denial triggers
Denial Risk & Authorization Triggers — Claims for drugs flagged with requirement codes (PA, QL, Q/T, MME) may be denied if required prior authorization or documentation is not obtained. Providers should follow the PA process and supply supporting documentation to avoid payment denials.
- Examples of denial triggers: absence of PA when "PA" is indicated; exceeding Quantity Limits (QL) or Day Supply limits (5DS); exceeding Morphine Milligram Equivalent (MME) thresholds.
- Claim dollar over‑limit (+) will require PA review (claims > $10,000).
- Many specialty products and oncology/transplant agents are frequently marked PA and may also have QL or LDD requirements.
Prior authorization for opioid MME and cumulative stimulant limits
Safety limits that trigger prior authorization — AmeriHealth applies specific safety thresholds that require PA when exceeded, including opioid MME limits and cumulative stimulant dose limits.
- Opioid MME limit: prior authorization is required for opioid dosing that exceeds 90 MME per day. The MME calculation aggregates all opioid products and potencies.
- Cumulative stimulant limits: PA is required when total daily stimulant dose by active ingredient exceeds specified thresholds (examples: amphetamine 60 mg/day; methylphenidate 72 mg/day; lisdexamfetamine 70 mg/day; dexmethylphenidate 40 mg/day; serdexmethylphenidate 52.3 mg/day).
- High‑dose stimulant and opioid claims may be denied without an approved PA.
How to submit PA and formulary exceptions
How to submit prior authorization and formulary exception requests — Providers may submit PA requests electronically (ePA platforms such as SureScripts™) or by fax using the AmeriHealth/PBM prior authorization form. Formulary tier‑exception requests require documentation of trials or contraindications to alternatives as specified.
- ePA (e.g., SureScripts™) can yield real‑time approvals in the office.
- Fax prior authorization and formulary exception requests to the PBM at 1‑888‑671‑5285; forms and instructions are available at https://www.amerihealth.com/resources/for-providers/policies-and-guidelines/index.html.
- Tier exceptions: when applicable, requests for preferred coverage of a non‑preferred drug generally require trial of, or contraindication to, at least three formulary alternatives. Tier exceptions are not available for some tiers/plans—refer to the member benefit booklet.
Requirement abbreviations and required documentation (legend)
Requirement abbreviations and documentation legend — The formulary uses standardized abbreviations to indicate utilization management and documentation needs. Providers must supply documentation consistent with the legend when submitting PA or appeals.
- Key abbreviations: PA = Prior Authorization; QL = Quantity Limits Apply; Q/T = Quantity Over Time; AL = Age Limit; 5DS = Day Supply Limit; LDD = Limited Distribution Drug; SP = Specialty Drug; MME = Morphine Milligram Equivalent; + = Claim Dollar Limit; R = Requires Rider.
- When a drug entry includes PA, providers must submit the PA request with clinical rationale and supporting records (e.g., prior therapy history, contraindications).
- The formulary rows may also include QL, MME, AL flags that indicate additional documentation or limits that must be met.
Provider‑impact procedures and coverage risk
Provider impact summary — Many drugs throughout the formulary are designated PA (Prior Authorization) and/or QL (Quantity Limits) — providers should review the drug‑specific formulary row for requirements before prescribing to avoid claim denials and to ensure timely access.
- PA, QL, Q/T and MME flags appear across specialty, oncology, cardiovascular, CNS, and other therapeutic classes.
- PA applies to all formulations of a listed product unless otherwise noted; specialty or limited distribution drugs may have additional handling and documentation requirements (SP, LDD).
- If prior authorization is denied, the prescribing provider and member will be notified with instructions for appeals; appeals processes are described in denial communications.
Initial Therapy Requirements
Step Therapy / Prior Trials
| Requirement | Interpretation / Action |
|---|---|
| Prior authorization and other utilization controls (PA, QL, AL, 5DS) may be applied | Procedures such as prior authorization, age limits, and quantity limits support safe prescribing; providers must obtain PA when a drug row indicates 'PA' prior to coverage |
| Step therapy implication | These procedures may require documentation of prior trials or contraindications to alternatives; however, no explicit multi-step (failed‑first) sequences are defined in the provided excerpt |
| Drug / Class | Step therapy / Step edits noted | Notes |
|---|---|---|
| General drug list entries | No explicit step‑therapy sequences are listed; individual drugs are annotated with PA, QL, AL, etc. | Providers should follow the per‑drug requirement flags shown in each row (PA = prior authorization; QL = quantity limits; AL = age limit) |
| Selected antibiotics and other agents (example: doxycycline entries) | Annotated with requirement flags (some formulations show PA or QL); no step order specified | See the drug row for formulation‑specific flags (e.g., Doxycycline DR 80mg = PA in chunk 76) |
| Drug / Group | Specialty / Oncology / Transplant Flag | Action required |
|---|---|---|
| Multiple oncology and transplant agents (examples: dasatinib, Erivedge, Erleada) | Frequently designated SP (Specialty) and many list PA in REQUIREMENTS/LIMITS | Prior authorization is required for entries marked 'PA'; explicit step therapy sequences are not provided in this excerpt |
| Broad oncology/transplant list (Rezurock, many others) | Entries often show 'NPD, SP' and 'PA' or 'PA, QL' where indicated | Providers must submit PA for PA‑flagged specialty agents prior to coverage |
| Product / Class | Step edit / PA applied? | Reference detail |
|---|---|---|
| Amphetamine‑containing products (various branded and generics) | Step edits and utilization controls may apply; many amphetamine entries show PA and QL | Examples: amphetamine aspartate/.../dextro- listed with REQUIREMENTS/LIMITS = PA (chunk 121); amphetamine tablet (Evekeo) = PA, QL, 5DS, MME (chunk 123) |
| Cumulative stimulant dosing | Claims exceeding agent‑specific cumulative daily dose limits require prior authorization | Agent thresholds referenced in coding (e.g., amphetamine 60 mg/day) — see stimulant limit rules |
| Drug / Note | Step therapy indicated? | Comment |
|---|---|---|
| Glatiramer acetate / glatopa and other entries | No explicit step therapy sequences provided in this excerpt | Some rows indicate NPD or SP which reflect non‑preferred or specialty pathways and associated PA/QL flags (chunk 151) |
| General formulary rows | Managed access indicated by tier flags (NPD, SP) and PA/QL where shown; step therapy not defined here | Follow per‑drug flags for prior authorization or quantity limits |
| Drug / Example | Step therapy / PA flag | Implication |
|---|---|---|
| Pregabalin formulations (caps, ER, solution) | Several pregabalin entries are flagged PA or PA, QL depending on formulation | Providers must obtain PA for formulations listed with PA prior to coverage; no step algorithm provided |
| Pramipexole (and similar CNS agents) | Some entries show PA or QL as requirement flags | PA/QL indicate managed access; follow the drug row requirements |
| Drug | Step therapy / Requirement | Action |
|---|---|---|
| Eltrombopag | Requirements/Limits = PA (and appears as G, SP in list) | Prior authorization required for eltrombopag formulations listed with PA prior to coverage |
| Drug / Type | PA / QL indicated? | Notes |
|---|---|---|
| Sildenafil citrate (various strengths) and related products | Listed with REQUIREMENTS/LIMITS = PA for many formulations | Specialty or PA flags apply to some formulations; follow per‑drug PA requirements |
| Tadalafil (generic Adcirca / Cialis) and Tadliq Susp | Entries show PA or QL depending on formulation (chunk 235) | Some generics and specialty forms are subject to PA before coverage; no multi‑step sequences specified |
| Drug / Example | Step therapy / PA flag | Guidance |
|---|---|---|
| Topical and dermatology agents (e.g., diclofenac 3% gel, Differin formulations) | Many entries show PA and/or AL and sometimes QL (chunk 251) | Follow per‑drug flags; no explicit step therapy sequencing shown in this excerpt |
| Relenza and other respiratory agents | Relenza is annotated QL (chunk 90) | Quantity limits or PA apply as indicated on the drug row; step therapy not listed |
Quantity Limits and Day Supply Restrictions
Formulary Abbreviations and Definitions
Specialty and Site-of-Care Notes
Formulary Governance
The formulary is reviewed and maintained by a Pharmacy and Therapeutics Committee composed of physicians and pharmacists to ensure included drugs meet standards for safety, effectiveness, and value. The PBM routinely monitors drugs and applies safety edits (such as age limits, quantity limits, MME limits, and cumulative stimulant limits) to align prescribing with FDA guidance and clinical practice.
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