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    v1.0.28
    OpenPayerBilling CodesTemporary National Codes (Non-Medicare)HCPCS hcpcs-s9430-pharmacy-compounding-dispensing
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    HCPCS Level II S9430: Pharmacy Compounding and Dispensing Services

    HCPCS Level II code S9430 describes pharmacy compounding and dispensing services, representing professional pharmacy activities to prepare and dispense personalized medications; service type is compounding and dispensing, and the typical site of service is pharmacy or outpatient clinic-based pharmacy where individualized medications are prepared for patient use.

    For related coverage guidance, see recent payer policy updates: Fixed Wing Air Ambulance Transport, Air Ambulance, Ambulance Services (for New Mexico Only).

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A patient with a chronic dermatologic condition (for example severe eczema or psoriasis) presents to a retail or specialty pharmacy with a prescription for a customized topical formulation that is not commercially available. The prescriber orders a compounded topical steroid/antibiotic/emollient preparation to a specific concentration and vehicle for targeted site application over a 30‑day supply.

    The clinical workflow: the prescriber sends a written or electronic prescription specifying ingredients, concentrations, dosage form, and directions. The pharmacist reviews the prescription for safety, verifies allergies and drug interactions, performs compounding per USP <795>/<797> or state board standards, documents lot numbers and beyond‑use dating, dispenses the product with counseling, and bills pharmacy compounding and dispensing services using S9430. Medication administration occurs at home by the patient with documented patient education and follow up arranged with the prescriber for effectiveness and adverse effects.

    Related Diagnoses

    ICD-10 CodeDescriptionClinical Relevance
    L20.9Atopic dermatitis, unspecifiedCommon indication for custom topical steroids or emollient combinations requiring compounding.
    L40.9Psoriasis, unspecifiedMay require tailored topical adjuncts or preparations not commercially available.
    L98.9Disorder of skin and subcutaneous tissue, unspecifiedUsed when a specific diagnosis is not precise but a compounded topical or topical antibiotic is prescribed.
    T88.7XXAUnspecified adverse effect of drug or medicament, initial encounterRelevant when a patient requires a compounded alternative due to intolerance to standard formulations.
    R21Rash and other nonspecific skin eruptionShort‑term need for customized topical therapies when standard products fail or cause irritation.

    Related Modifiers

    8 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    54Modifier ‑54 (“Surgical care only”) is appended to a CPT surgical procedure when the reporting surgeon performs the intraoperative (surgical) component but does not furnish the preoperative and/or…- Use modifier -54 when the reporting surgeon provided only the intraoperative (surgical) component of a procedure and preoperative and/or postoperative management has been or will be provided by…
    55Modifier –55 indicates the billing provider furnished only postoperative management for a procedure that has a global surgical period. According to AAPC, this modifier is appended to the same CPT…- Use modifier -55 when billing the same CPT surgical code that has a 10- or 90-day global period and you, as a provider other than the original surgeon, furnished ONLY postoperative management (no…
    56Modifier ‑56 indicates the reporting provider furnished only the preoperative management for a surgical procedure and did not perform the intraoperative or postoperative care. It is used in…- Use Modifier -56 when a provider performs only the preoperative management in a split‑care situation (one physician manages preop care while a different physician performs the intraoperative…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    333600000XPharmacyA facility used by pharmacists for the compounding and dispensing of medicinal preparations and other associated professional and administrative servi…
    208D00000XGeneral Practice PhysicianA physician who specializes in the general practice of diagnosing, treating, and managing patients with a variety of illnesses and conditions.
    207Q00000XFamily Medicine PhysicianFamily Medicine is the medical specialty which is concerned with the total health care of the individual and the family. It is the specialty in breadt…
    2084B0040XBehavioral Neurology & Neuropsychiatry PhysicianBehavioral Neurology & Neuropsychiatry is a medical subspecialty involving the diagnosis and treatment of neurologically based behavioral issues.
    364SM0705XMedical-Surgical Clinical Nurse SpecialistPhysician Assistants & Advanced Practice Nursing Providers · Clinical Nurse Specialist
    1223P0221XPediatric DentistryAn age-defined specialty that provides both primary and comprehensive preventive and therapeutic oral health care for infants and children through ado…
    207RH0005XHypertension Specialist PhysicianA Hypertension Specialist is a physician who concentrates on all aspects of the diagnosis and treatment of hypertension.
    2471R0002XRadiation Therapy Radiologic TechnologistA radiologic technologist who specializes in radiation therapy and is appropriately educated and trained, consistent with nationally recognized standa…

    Related ICD-10-CM Codes

    29 rows

    ICD-10-CM CodeDescription
    B35.1Tinea unguium
    B37.0Candidal stomatitis
    E10.65Type 1 diabetes mellitus with hyperglycemia
    E11.65Type 2 diabetes mellitus with hyperglycemia
    E78.5Hyperlipidemia, unspecified
    F11.20Opioid dependence, uncomplicated
    I10Essential (primary) hypertension
    J44.9Chronic obstructive pulmonary disease, unspecified
    J45.909Unspecified asthma, uncomplicated
    K50.90Crohn's disease, unspecified, without complications

    Showing 1–10 of 29

    Related Payer Policy Updates

    Specialty: Emergency & Medical Transportation1 / 3

    10 rows

    PolicyPayerEffective Date
    Fixed Wing Air Ambulance TransportCigna2026-08-15
    Air AmbulanceAmbetter Georgia2026-08-01
    Ambulance Services (for New Mexico Only)UnitedHealthcare2026-08-01
    Ambulance Services (for Tennessee Only)UnitedHealthcare2026-08-01
    Clinical Policy: Air AmbulanceArizona Complete Health2026-08-01
    Air AmbulanceCentene2026-08-01
    Clinical Policy: Air AmbulanceCentene2026-08-01
    Clinical Policy: Air AmbulanceAmbetter Nevada2026-08-01
    Ambulance TransportProvidence Health Plan2026-07-01
    Air ambulance transport coverage criteriaeocco2026-07-01

    Related Codes

    HCPCS-LEVEL-II-S2152-SOLID-ORGAN-TRANSPLANTATION-GLOBAL-CARE

    HCPCS Level II S2152: Solid Organ Procurement and Transplantation

    HCPCS-LEVEL-II-S2266-INDUCED-ABORTION-29-TO-31-WEEKS

    HCPCS Level II S2266: Induced Abortion, 29 to 31 Weeks

    HCPCS-LEVEL-II-S3630-EOSINOPHIL-COUNT-BLOOD-DIRECT

    HCPCS Level II S3630: Eosinophil Count, Blood, Direct

    HCPCS-LEVEL-II-S4017-INCOMPLETE-ART-CYCLE-CANCELLED-PRIOR-TO-STIMULATION

    HCPCS Level II S4017: Incomplete Cycle — Cancelled Prior to Stimulation

    HCPCS-LEVEL-II-S8055-ULTRASOUND-GUIDANCE-MULTIFETAL-REDUCTION-TC

    HCPCS Level II S8055: Ultrasound Guidance for Multifetal Pregnancy Reduction

    HCPCS-LEVEL-II-S8940-EQUESTRIAN-HIPPOTHERAPY-PER-SESSION

    HCPCS Level II S8940: Equestrian/Hippotherapy, Per Session

    HCPCS-LEVEL-II-S9024-PARANASAL-SINUS-ULTRASOUND

    HCPCS Level II S9024: Paranasal Sinus Ultrasound

    HCPCS-LEVEL-II-S9366-HOME-TPN-1-2L-PER-DAY-HOME-INFUSION

    HCPCS Level II S9366: Home Infusion TPN, 1–2 L/day

    HCPCS-LEVEL-II-S9446-GROUP-PATIENT-EDUCATION-NON-PHYSICIAN

    HCPCS S9446: Patient Education, Non-Physician Provider, Group, Per Session

    HCPCS-LEVEL-II-S9451-EXERCISE-CLASS-NON-PHYSICIAN-SESSION

    HCPCS S9451: Exercise Classes, Non-Physician Provider, Per Session

    Showing 1–10 of 532

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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