HCPCS Level II code S9375 designates a per diem charge for home infusion hydration therapy covering administrative services, professional pharmacy services, care coordination, and all necessary supplies and equipment when providing more than one liter but no more than two liters of hydration per day; drugs and nursing visits are billed separately. This code matters nationally as home-based infusion and hydration services expand to support care outside traditional facilities, affecting payer coverage, reimbursement pathways, and care coordination models.

Key payers referenced include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise overview of the clinical service represented by the code, typical site-of-service implications, and what to expect in payer coverage discussions. The publication outlines common billing considerations and benchmarks, summarizes policy and coding updates that affect per diem home infusion services, and provides clinical context for appropriate use of the code.

The report is intended for billing professionals, pharmacy and home infusion program managers, and policy analysts seeking a national perspective on how S9375 is used, how payers approach coverage, and what operational and documentation elements commonly influence payment and utilization. Data not available in the input are noted where relevant.