HCPCS Level II S9347: Home Infusion Uninterrupted Long-Term Controlled-Rate

HCPCS Level II code S9347 represents a per diem administrative and professional pharmacy service for home infusion therapy, uninterrupted, long-term, controlled-rate intravenous or subcutaneous infusion therapy (for example, epoprostenol), encompassing care coordination and necessary supplies and equipment; service type is home infusion therapy administrative and pharmacy services, and the typical site of service is the patient’s home with nursing and drug administration billed separately.

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HCPCS Level II S9347: Home Infusion Uninterrupted Long-Term Controlled-Rate

Customize your policy alerts

Sign up for hcpcs S9347 policy alerts

Get alerted when payer policies referencing S9347 are released or updated.

Monitor payer policy activity

Receive email alerts as soon as relevant payer policies are published or updated.

Clinical & Coding Specifications

Clinical Context

A 58-year-old patient with pulmonary arterial hypertension (PAH) is discharged from the hospital to continue long-term continuous intravenous epoprostenol infusion at home. The patient has a tunneled central venous catheter placed during hospitalization and requires uninterrupted, controlled-rate infusion delivered via a programmable ambulatory infusion pump. A home infusion pharmacy coordinates drug preparation and delivery, provides the infusion pump and supplies, arranges nursing visits for catheter care and pump teaching, and performs ongoing clinical monitoring and care coordination with the prescribing pulmonologist and the patient’s primary care clinician. Documentation includes the medication order, infusion pump settings, catheter assessment, teaching logs, nursing visit notes, and communication notes with the prescriber.

Typical workflow:

Initial home care set-up visit by home infusion nurse to confirm pump programming, line integrity, and patient/caregiver competence.
Daily or per-diem administrative and clinical services provided by the pharmacy and care coordination team (scheduling deliveries, remote monitoring, insurance authorization, troubleshooting pump alarms) billed under S9347 per diem; drug product and nursing visits billed separately using appropriate HCPCS/CPT and supply/drug codes.
Routine periodic nursing visits for site/catheter assessment, dressing changes, and documentation; emergency nursing or clinician contact managed as needed.
Ongoing interdisciplinary communication among pulmonology, pharmacy, home health nursing, and payer case management to maintain uninterrupted infusion and address adverse events or device issues.

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`96365`	Intravenous infusion, for therapy, prophylaxis, or diagnosis; initial, up to 1 hour	May be used for in-clinic or facility-based bolus or intermittent IV infusions preceding or supplementing ongoing home continuous infusion when billed during transition of care.
`96366`	Intravenous infusion, each additional hour (List separately in addition to code for primary procedure)	Used to report additional hours of monitored infusion in facility settings when documenting transition care prior to home per-diem billing.
`36415`	Collection of venous blood by venipuncture	Performed during baseline or periodic lab monitoring required for medication dosing and safety assessments prior to or during home infusion therapy.
`36561`	Insertion of tunneled centrally inserted central venous catheter, without subcutaneous port or pump, age 5 years or older	Procedure that may have been performed inpatient to provide long-term central venous access for continuous infusion; its presence is necessary for home epoprostenol therapy.
`99406`	Smoking and tobacco-use cessation counseling, intermediate, greater than 3 minutes up to 10 minutes	Example of typical E/M–adjunct counseling services that may occur in longitudinal management visits while coordinating home infusion care.

If additional CPT codes are needed for nursing visits, home health billing, or specific infusion pump management, those services are billed separately per payer policy and documentation.

Related Modifiers

6 rows

Modifier	Description	When to Use
22	Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…	- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
26	Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…	- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
52	Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…	- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
59	Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…	- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
76	Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…	- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
78	CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…	- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…

Related Provider Taxonomies

8 rows

Taxonomy Code	Specialty	Notes
251B00000X	Case Management Agency	An organization that is responsible for providing case management services. The agency provides services which assist an individual in gaining access…
207RG0300X	Geriatric Medicine (Internal Medicine) Physician	An internist who has special knowledge of the aging process and special skills in the diagnostic, therapeutic, preventive and rehabilitative aspects o…
207VH0002X	Hospice and Palliative Medicine (Obstetrics & Gynecology) Physician	An obstetrician/gynecologist with special knowledge and skills to prevent and relieve the suffering experienced by patients with life-limiting illness…
2084P0802X	Addiction Psychiatry Physician	Addiction Psychiatry is a subspecialty of psychiatry that focuses on evaluation and treatment of individuals with alcohol, drug, or other substance-re…
332000000X	Military/U.S. Coast Guard Pharmacy	A Department of Defense (DoD) or U.S. Coast Guard entity whose primary function is to store, prepare and dispense pharmaceuticals and other associated…
364SX0204X	Pediatric Oncology Clinical Nurse Specialist	Physician Assistants & Advanced Practice Nursing Providers · Clinical Nurse Specialist
315D00000X	Inpatient Hospice	A provider organization, or distinct part of the organization, which renders an interdisciplinary program providing palliative care, chiefly medical r…
364SP0808X	Psychiatric/Mental Health Clinical Nurse Specialist	Physician Assistants & Advanced Practice Nursing Providers · Clinical Nurse Specialist

HCPCS Level II S2152: Solid Organ Procurement and Transplantation

HCPCS-LEVEL-II-S2266-INDUCED-ABORTION-29-TO-31-WEEKS

HCPCS Level II S2266: Induced Abortion, 29 to 31 Weeks

HCPCS-LEVEL-II-S3630-EOSINOPHIL-COUNT-BLOOD-DIRECT

HCPCS Level II S3630: Eosinophil Count, Blood, Direct

HCPCS-LEVEL-II-S4017-INCOMPLETE-ART-CYCLE-CANCELLED-PRIOR-TO-STIMULATION

HCPCS Level II S4017: Incomplete Cycle — Cancelled Prior to Stimulation

HCPCS-LEVEL-II-S8055-ULTRASOUND-GUIDANCE-MULTIFETAL-REDUCTION-TC

HCPCS Level II S8055: Ultrasound Guidance for Multifetal Pregnancy Reduction

HCPCS-LEVEL-II-S8940-EQUESTRIAN-HIPPOTHERAPY-PER-SESSION

HCPCS Level II S8940: Equestrian/Hippotherapy, Per Session

HCPCS-LEVEL-II-S9024-PARANASAL-SINUS-ULTRASOUND

HCPCS Level II S9024: Paranasal Sinus Ultrasound

HCPCS-LEVEL-II-S9366-HOME-TPN-1-2L-PER-DAY-HOME-INFUSION

HCPCS Level II S9366: Home Infusion TPN, 1–2 L/day

HCPCS-LEVEL-II-S9446-GROUP-PATIENT-EDUCATION-NON-PHYSICIAN

HCPCS S9446: Patient Education, Non-Physician Provider, Group, Per Session

HCPCS-LEVEL-II-S9451-EXERCISE-CLASS-NON-PHYSICIAN-SESSION

HCPCS S9451: Exercise Classes, Non-Physician Provider, Per Session

Showing 1–10 of 532

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.

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Clinical & Coding Specifications

Clinical Context

Typical workflow:

Initial home care set-up visit by home infusion nurse to confirm pump programming, line integrity, and patient/caregiver competence.
Daily or per-diem administrative and clinical services provided by the pharmacy and care coordination team (scheduling deliveries, remote monitoring, insurance authorization, troubleshooting pump alarms) billed under S9347 per diem; drug product and nursing visits billed separately using appropriate HCPCS/CPT and supply/drug codes.
Routine periodic nursing visits for site/catheter assessment, dressing changes, and documentation; emergency nursing or clinician contact managed as needed.
Ongoing interdisciplinary communication among pulmonology, pharmacy, home health nursing, and payer case management to maintain uninterrupted infusion and address adverse events or device issues.

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`96365`	Intravenous infusion, for therapy, prophylaxis, or diagnosis; initial, up to 1 hour	May be used for in-clinic or facility-based bolus or intermittent IV infusions preceding or supplementing ongoing home continuous infusion when billed during transition of care.
`96366`	Intravenous infusion, each additional hour (List separately in addition to code for primary procedure)	Used to report additional hours of monitored infusion in facility settings when documenting transition care prior to home per-diem billing.
`36415`	Collection of venous blood by venipuncture	Performed during baseline or periodic lab monitoring required for medication dosing and safety assessments prior to or during home infusion therapy.
`36561`	Insertion of tunneled centrally inserted central venous catheter, without subcutaneous port or pump, age 5 years or older	Procedure that may have been performed inpatient to provide long-term central venous access for continuous infusion; its presence is necessary for home epoprostenol therapy.
`99406`	Smoking and tobacco-use cessation counseling, intermediate, greater than 3 minutes up to 10 minutes	Example of typical E/M–adjunct counseling services that may occur in longitudinal management visits while coordinating home infusion care.

If additional CPT codes are needed for nursing visits, home health billing, or specific infusion pump management, those services are billed separately per payer policy and documentation.

Related Modifiers

6 rows

Modifier	Description	When to Use
22	Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…	- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
26	Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…	- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
52	Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…	- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
59	Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…	- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
76	Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…	- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
78	CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…	- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…

Related Provider Taxonomies

8 rows

Taxonomy Code	Specialty	Notes
251B00000X	Case Management Agency	An organization that is responsible for providing case management services. The agency provides services which assist an individual in gaining access…
207RG0300X	Geriatric Medicine (Internal Medicine) Physician	An internist who has special knowledge of the aging process and special skills in the diagnostic, therapeutic, preventive and rehabilitative aspects o…
207VH0002X	Hospice and Palliative Medicine (Obstetrics & Gynecology) Physician	An obstetrician/gynecologist with special knowledge and skills to prevent and relieve the suffering experienced by patients with life-limiting illness…
2084P0802X	Addiction Psychiatry Physician	Addiction Psychiatry is a subspecialty of psychiatry that focuses on evaluation and treatment of individuals with alcohol, drug, or other substance-re…
332000000X	Military/U.S. Coast Guard Pharmacy	A Department of Defense (DoD) or U.S. Coast Guard entity whose primary function is to store, prepare and dispense pharmaceuticals and other associated…
364SX0204X	Pediatric Oncology Clinical Nurse Specialist	Physician Assistants & Advanced Practice Nursing Providers · Clinical Nurse Specialist
315D00000X	Inpatient Hospice	A provider organization, or distinct part of the organization, which renders an interdisciplinary program providing palliative care, chiefly medical r…
364SP0808X	Psychiatric/Mental Health Clinical Nurse Specialist	Physician Assistants & Advanced Practice Nursing Providers · Clinical Nurse Specialist

HCPCS Level II S2152: Solid Organ Procurement and Transplantation

HCPCS-LEVEL-II-S2266-INDUCED-ABORTION-29-TO-31-WEEKS

HCPCS Level II S2266: Induced Abortion, 29 to 31 Weeks

HCPCS-LEVEL-II-S3630-EOSINOPHIL-COUNT-BLOOD-DIRECT

HCPCS Level II S3630: Eosinophil Count, Blood, Direct

HCPCS-LEVEL-II-S4017-INCOMPLETE-ART-CYCLE-CANCELLED-PRIOR-TO-STIMULATION

HCPCS Level II S4017: Incomplete Cycle — Cancelled Prior to Stimulation

HCPCS-LEVEL-II-S8055-ULTRASOUND-GUIDANCE-MULTIFETAL-REDUCTION-TC

HCPCS Level II S8055: Ultrasound Guidance for Multifetal Pregnancy Reduction

HCPCS-LEVEL-II-S8940-EQUESTRIAN-HIPPOTHERAPY-PER-SESSION

HCPCS Level II S8940: Equestrian/Hippotherapy, Per Session

HCPCS-LEVEL-II-S9024-PARANASAL-SINUS-ULTRASOUND

HCPCS Level II S9024: Paranasal Sinus Ultrasound

HCPCS-LEVEL-II-S9366-HOME-TPN-1-2L-PER-DAY-HOME-INFUSION

HCPCS Level II S9366: Home Infusion TPN, 1–2 L/day

HCPCS-LEVEL-II-S9446-GROUP-PATIENT-EDUCATION-NON-PHYSICIAN

HCPCS S9446: Patient Education, Non-Physician Provider, Group, Per Session

HCPCS-LEVEL-II-S9451-EXERCISE-CLASS-NON-PHYSICIAN-SESSION

HCPCS S9451: Exercise Classes, Non-Physician Provider, Per Session

Showing 1–10 of 532

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

OpenPayer

HCPCS Level II S9347: Home Infusion Uninterrupted Long-Term Controlled-Rate

Sign up for hcpcs S9347 policy alerts

OpenPayer

HCPCS Level II S9347: Home Infusion Uninterrupted Long-Term Controlled-Rate

Sign up for hcpcs S9347 policy alerts

Clinical & Coding Specifications

Clinical Context

Related CPT Codes

Related Modifiers

Related Provider Taxonomies

Related Codes

References

Clinical & Coding Specifications

Clinical Context

Related CPT Codes

Related Modifiers

Related Provider Taxonomies

Related Codes

References

HCPCS Level II S9347: Home Infusion Uninterrupted Long-Term Controlled-Rate

Sign up for hcpcs S9347 policy alerts

HCPCS Level II S9347: Home Infusion Uninterrupted Long-Term Controlled-Rate

Sign up for hcpcs S9347 policy alerts

Clinical & Coding Specifications

Clinical Context

Related CPT Codes

Related Modifiers

Related Provider Taxonomies

Related Codes

What does HCPCS code S9347 cover and what is billed separately?

What documentation and workflow elements support billing S9347?

Which modifiers are applicable to S9347 and when are they used?

Which other CPT codes or services commonly appear alongside S9347?

What diagnoses are commonly associated with billing S9347?

References

Clinical & Coding Specifications

Clinical Context

Related CPT Codes

Related Modifiers

Related Provider Taxonomies

Related Codes

What does HCPCS code S9347 cover and what is billed separately?

What documentation and workflow elements support billing S9347?

Which modifiers are applicable to S9347 and when are they used?

Which other CPT codes or services commonly appear alongside S9347?

What diagnoses are commonly associated with billing S9347?

References