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    v1.0.30
    OpenPayerBilling CodesTemporary National Codes (Non-Medicare)HCPCS hcpcs-s9347-home-infusion-therapy-long-term-controlled-rate
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    HCPCS Level II S9347: Home Infusion Uninterrupted Long-Term Controlled-Rate

    HCPCS Level II code S9347 represents a per diem administrative and professional pharmacy service for home infusion therapy, uninterrupted, long-term, controlled-rate intravenous or subcutaneous infusion therapy (for example, epoprostenol), encompassing care coordination and necessary supplies and equipment; service type is home infusion therapy administrative and pharmacy services, and the typical site of service is the patient’s home with nursing and drug administration billed separately.

    For related coverage guidance, see recent payer policy updates: Ambulance and Medical Transport Services (Ground, Air and Water) Corporate Medical Policy, Emergency Air/Water Ambulance Services Medical Guideline, Non-Emergent Ambulance Services.

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    Clinical & Coding Specifications

    Clinical Context

    A 58-year-old patient with pulmonary arterial hypertension (PAH) is discharged from the hospital to continue long-term continuous intravenous epoprostenol infusion at home. The patient has a tunneled central venous catheter placed during hospitalization and requires uninterrupted, controlled-rate infusion delivered via a programmable ambulatory infusion pump. A home infusion pharmacy coordinates drug preparation and delivery, provides the infusion pump and supplies, arranges nursing visits for catheter care and pump teaching, and performs ongoing clinical monitoring and care coordination with the prescribing pulmonologist and the patient’s primary care clinician. Documentation includes the medication order, infusion pump settings, catheter assessment, teaching logs, nursing visit notes, and communication notes with the prescriber.

    Typical workflow:

    • Initial home care set-up visit by home infusion nurse to confirm pump programming, line integrity, and patient/caregiver competence.

    • Daily or per-diem administrative and clinical services provided by the pharmacy and care coordination team (scheduling deliveries, remote monitoring, insurance authorization, troubleshooting pump alarms) billed under S9347 per diem; drug product and nursing visits billed separately using appropriate HCPCS/CPT and supply/drug codes.

    • Routine periodic nursing visits for site/catheter assessment, dressing changes, and documentation; emergency nursing or clinician contact managed as needed.

    • Ongoing interdisciplinary communication among pulmonology, pharmacy, home health nursing, and payer case management to maintain uninterrupted infusion and address adverse events or device issues.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    96365Intravenous infusion, for therapy, prophylaxis, or diagnosis; initial, up to 1 hourMay be used for in-clinic or facility-based bolus or intermittent IV infusions preceding or supplementing ongoing home continuous infusion when billed during transition of care.
    96366Intravenous infusion, each additional hour (List separately in addition to code for primary procedure)Used to report additional hours of monitored infusion in facility settings when documenting transition care prior to home per-diem billing.
    36415Collection of venous blood by venipuncturePerformed during baseline or periodic lab monitoring required for medication dosing and safety assessments prior to or during home infusion therapy.
    36561Insertion of tunneled centrally inserted central venous catheter, without subcutaneous port or pump, age 5 years or olderProcedure that may have been performed inpatient to provide long-term central venous access for continuous infusion; its presence is necessary for home epoprostenol therapy.
    99406Smoking and tobacco-use cessation counseling, intermediate, greater than 3 minutes up to 10 minutesExample of typical E/M–adjunct counseling services that may occur in longitudinal management visits while coordinating home infusion care.

    If additional CPT codes are needed for nursing visits, home health billing, or specific infusion pump management, those services are billed separately per payer policy and documentation.

    Related Modifiers

    6 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    251B00000X
    207RG0300X
    207VH0002X
    2084P0802X
    332000000X
    364SX0204X
    315D00000X
    364SP0808X

    Related Payer Policy Updates

    Specialty: Emergency & Medical Transportation1 / 3

    10 rows

    PolicyPayerEffective Date
    Ambulance and Medical Transport Services (Ground, Air and Water) Corporate Medical Policybcbsvermont2026-10-01
    Emergency Air/Water Ambulance Services Medical GuidelineWPS Health Insurance2026-10-01
    Non-Emergent Ambulance ServicesConnectiCare2026-09-11
    Fixed Wing Air Ambulance TransportCigna2026-08-15
    Air AmbulanceAmbetter Georgia2026-08-01
    Ambulance Services (for New Mexico Only)UnitedHealthcare2026-08-01
    Ambulance Services (for Tennessee Only)UnitedHealthcare2026-08-01
    Clinical Policy: Air AmbulanceAmbetter Nevada2026-08-01
    Air AmbulanceCentene2026-08-01
    Clinical Policy: Air AmbulanceArizona Complete Health2026-08-01

    Related Codes

    HCPCS-LEVEL-II-S2152-SOLID-ORGAN-TRANSPLANTATION-GLOBAL-CARE

    HCPCS Level II S2152: Solid Organ Procurement and Transplantation

    HCPCS-LEVEL-II-S2266-INDUCED-ABORTION-29-TO-31-WEEKS

    HCPCS Level II S2266: Induced Abortion, 29 to 31 Weeks

    HCPCS-LEVEL-II-S3630-EOSINOPHIL-COUNT-BLOOD-DIRECT

    HCPCS Level II S3630: Eosinophil Count, Blood, Direct

    HCPCS-LEVEL-II-S4017-INCOMPLETE-ART-CYCLE-CANCELLED-PRIOR-TO-STIMULATION

    HCPCS Level II S4017: Incomplete Cycle — Cancelled Prior to Stimulation

    HCPCS-LEVEL-II-S8055-ULTRASOUND-GUIDANCE-MULTIFETAL-REDUCTION-TC

    HCPCS Level II S8055: Ultrasound Guidance for Multifetal Pregnancy Reduction

    HCPCS-LEVEL-II-S8940-EQUESTRIAN-HIPPOTHERAPY-PER-SESSION

    HCPCS Level II S8940: Equestrian/Hippotherapy, Per Session

    HCPCS-LEVEL-II-S9024-PARANASAL-SINUS-ULTRASOUND

    HCPCS Level II S9024: Paranasal Sinus Ultrasound

    HCPCS-LEVEL-II-S9366-HOME-TPN-1-2L-PER-DAY-HOME-INFUSION

    HCPCS Level II S9366: Home Infusion TPN, 1–2 L/day

    HCPCS-LEVEL-II-S9446-GROUP-PATIENT-EDUCATION-NON-PHYSICIAN

    HCPCS S9446: Patient Education, Non-Physician Provider, Group, Per Session

    HCPCS-LEVEL-II-S9451-EXERCISE-CLASS-NON-PHYSICIAN-SESSION

    HCPCS S9451: Exercise Classes, Non-Physician Provider, Per Session

    Showing 1–10 of 532

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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