Summary & Overview
HCPCS Level II S5012: 5% Dextrose with Potassium Chloride, 1000 ml
HCPCS Level II code S5012 designates a 1000 ml bag of 5% dextrose with potassium chloride—an intravenous solution used for fluid, electrolyte, and carbohydrate replacement. Nationally, such supply codes matter for hospitals, infusion providers, and home health agencies because they affect billing for commonly administered maintenance and replacement fluids.
Key payers in this analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise overview of clinical context for S5012, common sites where the product is administered, and what to expect in payer coverage considerations. The publication also outlines benchmark topics, relevant billing modifiers (listed separately), and points of policy attention that can influence claims processing and reimbursement for infusion supplies.
The piece is intended to help revenue cycle teams, clinicians involved in infusion therapy, and policy staff understand where S5012 fits within supply coding, common use cases, and the payer landscape. Data not available in the input will be clearly noted in applicable sections of the full publication.
Billing Code Overview
HCPCS Level II code S5012 describes 5% dextrose with potassium chloride, 1000 ml. This entry represents a compounded or packaged infusion fluid formulation combining a dextrose solution with added potassium chloride for electrolyte replacement and maintenance of fluid and carbohydrate needs.
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Service type: Intravenous infusion solution
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Typical site of service: Infusion centers, hospital inpatient and outpatient settings, skilled nursing facilities, and home infusion therapy
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Clinical & Coding Specifications
Clinical Context
A typical patient is an adult admitted to an inpatient ward or receiving care in an infusion center who requires intravenous maintenance or replacement fluids containing dextrose and potassium chloride, supplied as S5012 (5% dextrose with potassium chloride, 1000 ml). Common scenarios include: patients with hypokalemia requiring slow potassium repletion with concurrent glucose for patients with poor oral intake; patients receiving total or partial parenteral support where supplemental potassium is needed; patients with prolonged nausea, vomiting, or postoperative ileus where enteral intake is inadequate; and hospitalized medical patients on diuretics with documented potassium losses. The clinical workflow begins with clinician assessment and laboratory evaluation (including basic metabolic panel and serum potassium), an order placed in the electronic medical record specifying S5012 and infusion rate/volume, pharmacy verification and preparation, nursing administration via peripheral or central IV access with appropriate infusion pump settings, monitoring of vital signs and serial electrolytes, and documentation of fluid, electrolyte intake, and any adverse events. Typical sites of service include inpatient hospital units, observation units, emergency departments, and outpatient infusion centers.
Coding Specifications
| Modifier | Description | When to Use |
|---|---|---|
00 | General or default modifier (no specific CMS meaning) |