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    v1.0.28
    OpenPayerBilling CodesTemporary National Codes (Non-Medicare)HCPCS hcpcs-s2405-in-utero-repair-sacrococcygeal-teratoma
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    HCPCS Level II S2405: In Utero Repair of Sacrococcygeal Teratoma

    HCPCS Level II code S2405 describes surgical repair of a sacrococcygeal teratoma performed in utero; the service is a fetal surgical procedure (prenatal fetal surgery) typically performed in an operating room or specialized fetal surgery suite and is billed as an intrauterine operative fetal procedure.

    For related coverage guidance, see recent payer policy updates: Fixed Wing Air Ambulance Transport, Air Ambulance, Ambulance Services (for Tennessee Only).

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A pregnant patient in the second or early third trimester presents after detailed fetal imaging identifies a large sacrococcygeal teratoma with rapid growth, hydrops fetalis, or mass effect threatening fetal viability. The maternal-fetal medicine team coordinates a multidisciplinary workflow including fetal surgery, maternal anesthesia, neonatology, pediatric surgery, and transfusion services. Preoperative evaluation includes serial ultrasound and fetal MRI to assess tumor size, vascularity, and placental relationship, fetal echocardiography to evaluate for high-output cardiac failure, and maternal assessment for operative risk. Informed consent addresses fetal intervention risks, potential preterm delivery, and maternal complications.

    A typical in utero repair is scheduled in an operating room or dedicated fetal surgery suite with capabilities for open fetal surgery or fetoscopic techniques depending on tumor anatomy. Maternal general anesthesia with fetal monitoring is used; a hysterotomy or fetoscopic ports are placed, the tumor resected or debulked, and the uterine wall closed. Postoperative care includes maternal monitoring for hemorrhage and infection, tocolysis as indicated, serial imaging to assess residual tumor and fetal well-being, and planning for delivery and definitive neonatal surgery if needed. Discharge planning involves coordination with pediatric surgery and neonatal intensive care for anticipated postnatal care.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    59620Fetal monitoring during labor by intrauterine electrode; placementUsed for intraoperative or perioperative fetal monitoring when invasive fetal monitoring is required during fetal surgery.
    59425Antepartum fetal surveillance (nonstress test) up to 40 minutes, single or first episode of antepartum careUsed in pre- and post-procedure fetal surveillance visits.
    58340Hysterotomy during pregnancy for fetal surgeryRepresents the maternal hysterotomy approach when an open fetal repair with uterine incision is performed.
    33400Repair of congenital heart anomaly (illustrative major fetal cardiac procedures)Included as an analogous complex fetal surgical code; may be used for coordination when concurrent fetal cardiac interventions are performed (use clinically appropriate cardiac CPTs if performed).
    99499Unlisted evaluation and management serviceMay be used for unique preoperative multidisciplinary counseling or care coordination not represented by standard E/M codes (payer-dependent).

    Related Modifiers

    10 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    77Modifier 77 indicates that a previously performed procedure or service was legitimately repeated by a different physician or other qualified health care professional. The AMA’s CPT definition…- Use modifier 77 when a basic procedure or service already performed is repeated by a different physician or other qualified health care professional (for example, a second provider independently…
    91Modifier 91 — “Repeat Clinical Diagnostic Laboratory Test” — is appended when the exact same CPT laboratory test is performed more than once for the same patient on the same day because serial,…- Use modifier 91 when the exact same CPT laboratory test is performed more than once on the same patient on the same date because serial or repeated testing is medically necessary to monitor…
    99Modifier 99 is a placeholder modifier used when more modifiers apply to a single procedure than the claim form or electronic field allows. The AMA classifies it under Provider Services and Ambulatory…- Use CPT modifier -99 when more modifiers apply to a single procedure line than the claim form or payer field allows (CMS/Noridian: when more than four modifiers are needed); append modifier 99 on…

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    2080P0207XPediatric Hematology & Oncology PhysicianA pediatrician trained in the combination of pediatrics, hematology and oncology to recognize and manage pediatric blood disorders and cancerous disea…
    207K00000XAllergy & Immunology PhysicianAn allergist-immunologist is trained in evaluation, physical and laboratory diagnosis, and management of disorders involving the immune system. Select…
    207L00000XAnesthesiology PhysicianAn anesthesiologist is trained to provide pain relief and maintenance, or restoration, of a stable condition during and immediately following an opera…
    208D00000XGeneral Practice PhysicianA physician who specializes in the general practice of diagnosing, treating, and managing patients with a variety of illnesses and conditions.
    246QC1000XChemistry Pathology Specialist/TechnologistTechnologists, Technicians & Other Technical Service Providers · Specialist/Technologist, Pathology
    225400000XRehabilitation PractitionerA health care practitioner who trains or retrains individuals disabled by disease or injury to help them attain their maximum functional capacity.
    261QP0905XState or Local Public Health Clinic/CenterAmbulatory Health Care Facilities · Clinic/Center
    2085H0002XHospice and Palliative Medicine (Radiology) PhysicianA radiologist with special knowledge and skills to prevent and relieve the suffering experienced by patients with life-limiting illnesses. This specia…

    Related ICD-10-CM Codes

    14 rows

    ICD-10-CM CodeDescription
    P02.0Newborn affected by placenta previa
    P02.1Newborn affected by other forms of placental separation and hemorrhage
    P96.1Neonatal withdrawal symptoms from maternal use of drugs of addiction
    Q04.9Congenital malformation of brain, unspecified
    Q05.3Sacral spina bifida with hydrocephalus
    Q05.8Sacral spina bifida without hydrocephalus
    Q05.9Spina bifida, unspecified
    Q64.2Congenital posterior urethral valves
    Q75.4Mandibulofacial dysostosis
    Q79.9Congenital malformation of musculoskeletal system, unspecified

    Showing 1–10 of 14

    Related Payer Policy Updates

    Specialty: Emergency & Medical Transportation1 / 3

    9 rows

    PolicyPayerEffective Date
    Fixed Wing Air Ambulance TransportCigna2026-08-15
    Air AmbulanceAmbetter Georgia2026-08-01
    Ambulance Services (for Tennessee Only)UnitedHealthcare2026-08-01
    Ambulance Services (for New Mexico Only)UnitedHealthcare2026-08-01
    Clinical Policy: Air AmbulanceArizona Complete Health2026-08-01
    Clinical Policy: Air AmbulanceCentene2026-08-01
    Air AmbulanceCentene2026-08-01
    Clinical Policy: Air AmbulanceAmbetter Nevada2026-08-01
    Ambulance TransportProvidence Health Plan2026-07-01

    Related Codes

    HCPCS-LEVEL-II-S2152-SOLID-ORGAN-TRANSPLANTATION-GLOBAL-CARE

    HCPCS Level II S2152: Solid Organ Procurement and Transplantation

    HCPCS-LEVEL-II-S2266-INDUCED-ABORTION-29-TO-31-WEEKS

    HCPCS Level II S2266: Induced Abortion, 29 to 31 Weeks

    HCPCS-LEVEL-II-S3630-EOSINOPHIL-COUNT-BLOOD-DIRECT

    HCPCS Level II S3630: Eosinophil Count, Blood, Direct

    HCPCS-LEVEL-II-S4017-INCOMPLETE-ART-CYCLE-CANCELLED-PRIOR-TO-STIMULATION

    HCPCS Level II S4017: Incomplete Cycle — Cancelled Prior to Stimulation

    HCPCS-LEVEL-II-S8055-ULTRASOUND-GUIDANCE-MULTIFETAL-REDUCTION-TC

    HCPCS Level II S8055: Ultrasound Guidance for Multifetal Pregnancy Reduction

    HCPCS-LEVEL-II-S8940-EQUESTRIAN-HIPPOTHERAPY-PER-SESSION

    HCPCS Level II S8940: Equestrian/Hippotherapy, Per Session

    HCPCS-LEVEL-II-S9024-PARANASAL-SINUS-ULTRASOUND

    HCPCS Level II S9024: Paranasal Sinus Ultrasound

    HCPCS-LEVEL-II-S9366-HOME-TPN-1-2L-PER-DAY-HOME-INFUSION

    HCPCS Level II S9366: Home Infusion TPN, 1–2 L/day

    HCPCS-LEVEL-II-S9446-GROUP-PATIENT-EDUCATION-NON-PHYSICIAN

    HCPCS S9446: Patient Education, Non-Physician Provider, Group, Per Session

    HCPCS-LEVEL-II-S9451-EXERCISE-CLASS-NON-PHYSICIAN-SESSION

    HCPCS S9451: Exercise Classes, Non-Physician Provider, Per Session

    Showing 1–10 of 532

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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