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    OpenPayerBilling CodesTemporary CodesHCPCS hcpcs-q9982-flutemetamol-f18-pet-amyloid-imaging
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    HCPCS Q9982: Flutemetamol F-18 Diagnostic PET Radiotracer

    HCPCS Level II code Q9982 describes administration of flutemetamol F-18 for PET brain imaging, billed per study dose up to 5 millicuries; this is a diagnostic radiopharmaceutical used in nuclear medicine for amyloid imaging, typically provided as an injectable radiotracer and performed in hospital outpatient departments or imaging centers during a PET scan study.

    For related coverage guidance, see recent payer policy updates: B-Hemolytic Streptococcus Testing, Human Immunodeficiency Virus (HIV) — Coverage Criteria for Testing and Resistance Assays, Hepatitis Testing (A, B, C, D) Coverage Criteria.

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    Table of contents

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    • Billing CodesCPT, HCPCS, DRG & more
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    • ModifiersCPT modifiers & usage
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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is an adult referred by a neurologist or geriatrician for evaluation of suspected Alzheimer disease or other cognitive impairment where amyloid PET imaging will aid diagnosis. The patient presents with progressive memory loss, impaired executive function, or atypical cognitive decline despite prior conventional workup (history, physical exam, neuropsychological testing, and brain MRI/CT). The clinical workflow: the ordering clinician documents indication and obtains informed consent; the nuclear medicine or radiopharmacy prepares Flutemetamol F18 up to 5 millicuries per study dose; the patient arrives to an outpatient imaging center or hospital PET unit (typical site of service: hospital outpatient department or independent diagnostic testing facility); an intravenous dose of Q9982 is administered; after the appropriate uptake period the patient undergoes PET acquisition; images are interpreted by a board-certified nuclear medicine physician or radiologist; results are reported to the ordering clinician and used to support diagnostic assessment and care planning.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    78811Positron emission tomography (PET) radiopharmaceutical localization of brain, single study, qualitative or semiquantitativeCommonly reported for the PET acquisition associated with an amyloid radiotracer study when a CPT is required for imaging procedure separate from radiopharmaceutical billing
    78812Positron emission tomography (PET) brain, single study, quantitative analysisUsed when quantitative image analysis of amyloid burden is performed in conjunction with the diagnostic radiopharmaceutical administration
    78429PET imaging, other than cardiac, for tumor or disease evaluationOccasionally used as ancillary PET imaging CPT when facility coding maps brain amyloid PET under non-standard local coding schemas
    0001APositron emission tomography (PET) amyloid radiopharmaceutical(s) and imaging, interpretation and report, per study (Category I examples)Use when specific amyloid PET interpretation CPTs are applicable by payer; documents the professional interpretation component
    0002APET amyloid image processing and quantification, per studyUsed when advanced quantitative processing is performed as a separate billable service

    Related Modifiers

    6 rows

    ModifierDescriptionWhen to Use
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…
    82Modifier 82 is appended to a surgical CPT code to indicate that an attending physician acted as an assistant because a qualified resident surgeon was unavailable. In teaching hospitals it documents…- When to use: Append modifier 82 in teaching-hospital settings to indicate a physician served as an assistant surgeon because a qualified resident surgeon was unavailable (includes situations where…

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    208D00000XGeneral Practice PhysicianA physician who specializes in the general practice of diagnosing, treating, and managing patients with a variety of illnesses and conditions.
    2084P0800XPsychiatry PhysicianA Psychiatrist specializes in the prevention, diagnosis, and treatment of mental disorders, emotional disorders, psychotic disorders, mood disorders, …
    367A00000XAdvanced Practice MidwifeAdvanced practice midwifery encompasses the independent provision of care during pregnancy, childbirth, and the postpartum period; sexual and reproduc…
    363L00000XNurse Practitioner(1) A registered nurse provider with a graduate degree in nursing prepared for advanced practice involving independent and interdependent decision mak…
    364SC1501XCommunity Health/Public Health Clinical Nurse SpecialistPhysician Assistants & Advanced Practice Nursing Providers · Clinical Nurse Specialist
    2084P0015XPsychosomatic Medicine PhysicianPsychosomatic Medicine is subspecialty in the diagnosis and treatment of psychiatric disorders and symptoms in complex medically ill patients. This su…
    207YX0901XOtology & Neurotology PhysicianAn otolaryngologist who treats diseases of the ear and temporal bone, including disorders of hearing and balance. The additional training in otology a…
    364SW0102XWomen's Health Clinical Nurse SpecialistPhysician Assistants & Advanced Practice Nursing Providers · Clinical Nurse Specialist

    Related ICD-10-CM Codes

    24 rows

    ICD-10-CM CodeDescription
    E11.9Type 2 diabetes mellitus without complications
    F02.80Dementia in other diseases classified elsewhere, unspecified severity, without behavioral disturbance, psychotic disturbance, mood disturbance, and anxiety
    F03.90Unspecified dementia, unspecified severity, without behavioral disturbance, psychotic disturbance, mood disturbance, and anxiety
    F07.0Personality change due to known physiological condition
    F10.27Alcohol dependence with alcohol-induced persisting dementia
    G23.1Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]
    G30.0Alzheimer's disease with early onset
    G30.1Alzheimer's disease with late onset
    G30.9Alzheimer's disease, unspecified
    G31.1Senile degeneration of brain, not elsewhere classified

    Showing 1–10 of 24

    Related Payer Policy Updates

    Specialty: Infectious Disease1 / 3

    10 rows

    PolicyPayerEffective Date
    B-Hemolytic Streptococcus TestingOscar Health2026-10-01
    Human Immunodeficiency Virus (HIV) — Coverage Criteria for Testing and Resistance AssaysOscar Health2026-10-01
    Hepatitis Testing (A, B, C, D) Coverage CriteriaOscar Health2026-10-01
    Lyme Disease Testing Coverage CriteriaOscar Health2026-10-01
    Pathogen Panel TestingOscar Health2026-10-01
    Diagnostic Testing of Common Sexually Transmitted InfectionsOscar Health2026-10-01
    Testing for Diagnosis of Active or Latent TuberculosisOscar Health2026-10-01
    Testing for Vector-Borne InfectionsOscar Health2026-10-01
    Coronavirus Testing in the Outpatient SettingOscar Health2026-10-01
    Human Immunodeficiency Virus (HIV)blue cross blue shield - louisiana2026-09-15

    Related Codes

    HCPCS-LEVEL-II-Q4139-INJECTABLE-AMNIOMATRIX-BIODMATRIX-1-CC

    HCPCS Q4139: Amniomatrix or Biodmatrix, Injectable, 1 cc

    HCPCS-LEVEL-II-Q4256-AREA-BASED-PROCEDURAL-ADD-ON-PER-SQ-CM

    HCPCS Q4256: MLG-complete Skin Graft Material, Per Sq Cm

    HCPCS-LEVEL-II-Q5132-ADALIMUMAB-AFZB-ABRILADA-10MG-INJECTION

    HCPCS Level II Q5132: Injection, adalimumab-afzb (Abrilada), 10 mg

    HCPCS-Q0035-CARDIOKYMOGRAPHY-CARDIAC-MOTION-RECORDING

    HCPCS Level II Q0035: Cardiokymography

    HCPCS-Q0081-INFUSION-THERAPY-NON-CHEMOTHERAPEUTIC-PER-VISIT

    HCPCS Level II Q0081: Infusion Therapy, Non‑Chemotherapeutic, Per Visit

    HCPCS-Q0083-CHEMOTHERAPY-NON-INFUSION-ADMINISTRATION

    HCPCS Q0083: Chemotherapy Administration, Non-Infusion Methods

    HCPCS-Q0084-CHEMOTHERAPY-INFUSION-ADMINISTRATION-PER-VISIT

    HCPCS Q0084: Chemotherapy Infusion Administration, Per Visit

    HCPCS-Q0085-CHEMOTHERAPY-INFUSION-PLUS-OTHER-TECHNIQUES-PER-VISIT

    HCPCS Q0085: Chemotherapy Infusion Plus Other Technique(s), Per Visit

    HCPCS-Q0091-PAP-SMEAR-SPECIMEN-COLLECTION-TRANSPORT

    HCPCS Q0091: Screening Papanicolaou Smear Collection and Transport

    HCPCS-Q0092-PORTABLE-XRAY-EQUIPMENT-SETUP

    HCPCS Q0092: Set-up Portable X-ray Equipment

    Showing 1–10 of 629

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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