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    v1.0.28
    OpenPayerBilling CodesTemporary CodesHCPCS hcpcs-q4210-axolotl-graft-per-cm
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    HCPCS Level II Q4210: Axolotl Graft or Dualgraft, Per cm2

    HCPCS Level II code Q4210 describes billing for an axolotl graft or axolotl dualgraft, reported per square centimeter, a biologic graft product used in wound care and tissue repair; the service is a graft application/supply typically provided in outpatient wound care clinics, ambulatory surgical centers, or hospital outpatient departments and is reported when the axolotl-derived graft material is furnished and measured by surface area in square centimeters.

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    Clinical & Coding Specifications

    Clinical Context

    A 58-year-old patient with a chronic full-thickness lower extremity wound following trauma and prior graft failure is evaluated in an outpatient specialty wound clinic. After multidisciplinary assessment, the surgeon selects an axolotl graft or axolotl dualgraft and orders grafting by surface area. The procedure is performed in an ambulatory surgery center under monitored anesthesia care. The wound bed is prepared with debridement and hemostasis; the axolotl graft material is measured in square centimeters and applied to the recipient site, secured with sutures or adhesive dressings. Postoperative care includes dressing changes, infection surveillance, and scheduled outpatient follow-up for graft take assessment and possible revision if needed.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    11042Debridement, subcutaneous tissue, first 20 sq cm or lessOften performed immediately prior to graft placement to prepare the wound bed.
    11043Debridement, muscle and/or fascia, first 20 sq cm or lessUsed when deeper debridement is required before grafting.
    15271Application of skin substitute graft to trunk, arms, legs; first 100 sq cm or lessComparable coding for application of a biologic skin substitute by surface area; used as related reference for graft sizing and reporting.
    15275Application of skin substitute graft to a single wound; larger than 100 sq cmUsed when graft surface area exceeds 100 sq cm and larger-area grafting is performed.
    13131Repair, complex, trunk/arm/leg, 2.5 cm to 7.5 cmMay be performed for wound edge reconstruction or closure adjunctive to grafting in the same session.

    Related Modifiers

    8 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    54Modifier ‑54 (“Surgical care only”) is appended to a CPT surgical procedure when the reporting surgeon performs the intraoperative (surgical) component but does not furnish the preoperative and/or…- Use modifier -54 when the reporting surgeon provided only the intraoperative (surgical) component of a procedure and preoperative and/or postoperative management has been or will be provided by…
    55Modifier –55 indicates the billing provider furnished only postoperative management for a procedure that has a global surgical period. According to AAPC, this modifier is appended to the same CPT…- Use modifier -55 when billing the same CPT surgical code that has a 10- or 90-day global period and you, as a provider other than the original surgeon, furnished ONLY postoperative management (no…
    56Modifier ‑56 indicates the reporting provider furnished only the preoperative management for a surgical procedure and did not perform the intraoperative or postoperative care. It is used in…- Use Modifier -56 when a provider performs only the preoperative management in a split‑care situation (one physician manages preop care while a different physician performs the intraoperative…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    207P00000XEmergency Medicine PhysicianAn emergency physician focuses on the immediate decision making and action necessary to prevent death or any further disability both in the pre-hospit…
    208100000XPhysical Medicine & Rehabilitation PhysicianPhysical medicine and rehabilitation, also referred to as rehabilitation medicine, is the medical specialty concerned with diagnosing, evaluating, and…
    261QX0100XOccupational Medicine Clinic/CenterAmbulatory Health Care Facilities · Clinic/Center
    2084A0401XAddiction Medicine (Psychiatry & Neurology) PhysicianA doctor of osteopathy board eligible/certified in the field of Psychiatry by the American Osteopathic Board of Neurology and Psychiatry is able to ob…
    225XF0002XFeeding, Eating & Swallowing Occupational TherapistOccupational therapists provide interventions to clients of all ages with feeding, eating and swallowing difficulties. Occupational therapists provid…
    2080H0002XPediatric Hospice and Palliative Medicine PhysicianA pediatrician with special knowledge and skills to prevent and relieve the suffering experienced by patients with life-limiting illnesses. This speci…
    3336S0011XSpecialty PharmacyA pharmacy that dispenses generally low volume and high cost medicinal preparations to patients who are undergoing intensive therapies for illnesses t…
    207LP2900XPain Medicine (Anesthesiology) PhysicianAn anesthesiologist who provides a high level of care, either as a primary physician or consultant, for patients experiencing problems with acute, chr…

    Related ICD-10-CM Codes

    24 rows

    ICD-10-CM CodeDescription
    A46Erysipelas
    E10.621Type 1 diabetes mellitus with foot ulcer
    E11.621Type 2 diabetes mellitus with foot ulcer
    I83.019Varicose veins of right lower extremity with ulcer of unspecified site
    I83.11Varicose veins of right lower extremity with inflammation
    K91.89Other postprocedural complications and disorders of digestive system
    L03.115Cellulitis of right lower limb
    L03.116Cellulitis of left lower limb
    L89.309Pressure ulcer of unspecified buttock, unspecified stage
    L97.413Non-pressure chronic ulcer of right heel and midfoot with necrosis of muscle

    Showing 1–10 of 24

    Related Codes

    HCPCS-LEVEL-II-Q4139-INJECTABLE-AMNIOMATRIX-BIODMATRIX-1-CC

    HCPCS Q4139: Amniomatrix or Biodmatrix, Injectable, 1 cc

    HCPCS-LEVEL-II-Q4256-AREA-BASED-PROCEDURAL-ADD-ON-PER-SQ-CM

    HCPCS Q4256: MLG-complete Skin Graft Material, Per Sq Cm

    HCPCS-LEVEL-II-Q5132-ADALIMUMAB-AFZB-ABRILADA-10MG-INJECTION

    HCPCS Level II Q5132: Injection, adalimumab-afzb (Abrilada), 10 mg

    HCPCS-Q0035-CARDIOKYMOGRAPHY-CARDIAC-MOTION-RECORDING

    HCPCS Level II Q0035: Cardiokymography

    HCPCS-Q0081-INFUSION-THERAPY-NON-CHEMOTHERAPEUTIC-PER-VISIT

    HCPCS Level II Q0081: Infusion Therapy, Non‑Chemotherapeutic, Per Visit

    HCPCS-Q0083-CHEMOTHERAPY-NON-INFUSION-ADMINISTRATION

    HCPCS Q0083: Chemotherapy Administration, Non-Infusion Methods

    HCPCS-Q0084-CHEMOTHERAPY-INFUSION-ADMINISTRATION-PER-VISIT

    HCPCS Q0084: Chemotherapy Infusion Administration, Per Visit

    HCPCS-Q0085-CHEMOTHERAPY-INFUSION-PLUS-OTHER-TECHNIQUES-PER-VISIT

    HCPCS Q0085: Chemotherapy Infusion Plus Other Technique(s), Per Visit

    HCPCS-Q0091-PAP-SMEAR-SPECIMEN-COLLECTION-TRANSPORT

    HCPCS Q0091: Screening Papanicolaou Smear Collection and Transport

    HCPCS-Q0092-PORTABLE-XRAY-EQUIPMENT-SETUP

    HCPCS Q0092: Set-up Portable X-ray Equipment

    Showing 1–10 of 629

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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