HCPCS Q4347: Rampart dl Matrix, Per Square Centimeter

Medicare pays $133 on average nationally for this procedure.

HCPCS Level II code Q4347 describes billing for the Rampart dl matrix product, reported per square centimeter as an add-on supply used during wound care or surgical reconstruction; the service type is the provision of a biologic/dermal matrix graft and the typical site of service is operating room or outpatient wound care clinic where the matrix is applied in conjunction with a primary procedure.

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HCPCS Q4347: Rampart dl Matrix, Per Square Centimeter

Medicare pays $133 on average nationally for this procedure.

Customize your policy alerts

Sign up for hcpcs Q4347 policy alerts

Get alerted when payer policies referencing Q4347 are released or updated.

Monitor payer policy activity

Receive email alerts as soon as relevant payer policies are published or updated.

Clinical & Coding Specifications

Clinical Context

A typical patient is an adult with a full-thickness or complex partial-thickness wound of the skin after trauma, surgical excision of necrotic tissue, or chronic ulceration (for example, diabetic foot ulcer or pressure ulcer) requiring advanced wound coverage. The clinician prepares the wound bed with debridement and hemostasis, measures the defect in square centimeters, and applies an extracellular matrix product — in this case the Rampart dl matrix — as an adjunctive biologic scaffold to support tissue regeneration. The service is billed as an add-on, reported per square centimeter with Q4347 in addition to a primary procedure or application code that describes the debridement or wound repair.

Typical workflow:

The patient is evaluated in the outpatient wound clinic, emergency department, or operating room for a complex wound.
The primary procedure (for example, debridement, excision, or graft placement) is performed and documented with the appropriate CPT code(s).
The wound is measured and the provider documents the number of square centimeters of matrix applied.
The Rampart dl matrix is applied and secured according to manufacturer instructions; documentation includes product name, lot number, quantity (cm2), and clinical rationale.
Billing is submitted with the primary procedure CPT code(s) and the add-on HCPCS Level II code Q4347 with the appropriate modifier(s) to reflect circumstances of service or payer requirements.

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`11042`	Debridement, subcutaneous tissue (includes epidermis and dermis), first 20 sq cm or less	Commonly billed when surgical debridement precedes placement of the extracellular matrix to prepare the wound bed.
`11043`	Debridement, muscle and/or fascia, first 20 sq cm or less	Used for deeper debridement of wounds prior to matrix application when muscle or fascia are involved.
`15271`	Application of biologic (eg, collagen) graft to trunk, arms, legs; first 100 sq cm or less, or peripheral vascular bypass wound of lower extremity	May be used for primary reporting of biologic graft application; `Q4347` is billed additionally per square centimeter for the specific Rampart dl matrix as an add-on product.
`15275`	Application of skin substitute graft resulting in full-thickness skin loss, trunk, arms, legs; greater than 100 sq cm	Performed when larger surface areas require coverage; the matrix product may be used adjunctively and reported with `Q4347`.
`15734`	Muscle, myocutaneous, or fasciocutaneous flap with microvascular anastomosis	Performed for complex reconstruction; biologic matrix may be used adjunctively to support soft tissue coverage and reported as add-on if applicable.

Related Modifiers

6 rows

Modifier	Description	When to Use
22	Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…	- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
23	Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…	- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
52	Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…	- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
53	Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…	- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
62	Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…	- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
78	CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…	- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…

Related Provider Taxonomies

8 rows

Taxonomy Code	Specialty	Notes
174400000X	Specialist	An individual educated and trained in an applied knowledge discipline used in the performance of work at a level requiring knowledge and skills beyond…
207Q00000X	Family Medicine Physician	Family Medicine is the medical specialty which is concerned with the total health care of the individual and the family. It is the specialty in breadt…
363A00000X	Physician Assistant	A physician assistant is a person who has successfully completed an accredited education program for physician assistant, is licensed by the state and…
103T00000X	Psychologist	A psychologist is an individual who is licensed to practice psychology which is defined as the observation, description, evaluation, interpretation, a…
225XR0403X	Driving and Community Mobility Occupational Therapist	Occupational therapists can optimize and prolong an older driver's ability to drive safely and ease the transition to other forms of transportation if…
3336L0003X	Long Term Care Pharmacy	A pharmacy that dispenses medicinal preparations delivered to patients residing within an intermediate or skilled nursing facility, including intermed…
163WI0500X	Infusion Therapy Registered Nurse	Nursing Service Providers · Registered Nurse
2084P0301X	Brain Injury Medicine (Psychiatry & Neurology) Physician	A Brain Injury Medicine physician specializes in disorders of brain function due to injury and disease. These disorders encompass a range of medical,…

Related ICD-10-CM Codes

23 rows

ICD-10-CM Code	Description
E10.621	Type 1 diabetes mellitus with foot ulcer
E11.621	Type 2 diabetes mellitus with foot ulcer
I83.013	Varicose veins of right lower extremity with ulcer of ankle
I83.219	Varicose veins of right lower extremity with both ulcer of unspecified site and inflammation
I87.2	Venous insufficiency (chronic) (peripheral)
L03.115	Cellulitis of right lower limb
L03.116	Cellulitis of left lower limb
L89.151	Pressure ulcer of sacral region, stage 1
L89.152	Pressure ulcer of sacral region, stage 2
L89.153	Pressure ulcer of sacral region, stage 3

Showing 1–10 of 23

Related Payer Policy Updates

Specialty: Infectious Disease1 / 3

10 rows

Policy	Payer	Effective Date
B-Hemolytic Streptococcus Testing	Oscar Health	2026-10-01
Human Immunodeficiency Virus (HIV) — Coverage Criteria for Testing and Resistance Assays	Oscar Health	2026-10-01
Hepatitis Testing (A, B, C, D) Coverage Criteria	Oscar Health	2026-10-01
Lyme Disease Testing Coverage Criteria	Oscar Health	2026-10-01
Pathogen Panel Testing	Oscar Health	2026-10-01
Diagnostic Testing of Common Sexually Transmitted Infections	Oscar Health	2026-10-01
Coronavirus Testing in the Outpatient Setting	Oscar Health	2026-10-01
Testing for Vector-Borne Infections	Oscar Health	2026-10-01
Testing for Diagnosis of Active or Latent Tuberculosis	Oscar Health	2026-10-01
Human Immunodeficiency Virus (HIV)	blue cross blue shield - louisiana	2026-09-15

HCPCS Q4139: Amniomatrix or Biodmatrix, Injectable, 1 cc

HCPCS-LEVEL-II-Q4256-AREA-BASED-PROCEDURAL-ADD-ON-PER-SQ-CM

HCPCS Q4256: MLG-complete Skin Graft Material, Per Sq Cm

HCPCS-LEVEL-II-Q5132-ADALIMUMAB-AFZB-ABRILADA-10MG-INJECTION

HCPCS Level II Q5132: Injection, adalimumab-afzb (Abrilada), 10 mg

HCPCS-Q0035-CARDIOKYMOGRAPHY-CARDIAC-MOTION-RECORDING

HCPCS Level II Q0035: Cardiokymography

HCPCS-Q0081-INFUSION-THERAPY-NON-CHEMOTHERAPEUTIC-PER-VISIT

HCPCS Level II Q0081: Infusion Therapy, Non‑Chemotherapeutic, Per Visit

HCPCS-Q0083-CHEMOTHERAPY-NON-INFUSION-ADMINISTRATION

HCPCS Q0083: Chemotherapy Administration, Non-Infusion Methods

HCPCS-Q0084-CHEMOTHERAPY-INFUSION-ADMINISTRATION-PER-VISIT

HCPCS Q0084: Chemotherapy Infusion Administration, Per Visit

HCPCS-Q0085-CHEMOTHERAPY-INFUSION-PLUS-OTHER-TECHNIQUES-PER-VISIT

HCPCS Q0085: Chemotherapy Infusion Plus Other Technique(s), Per Visit

HCPCS-Q0091-PAP-SMEAR-SPECIMEN-COLLECTION-TRANSPORT

HCPCS Q0091: Screening Papanicolaou Smear Collection and Transport

HCPCS-Q0092-PORTABLE-XRAY-EQUIPMENT-SETUP

HCPCS Q0092: Set-up Portable X-ray Equipment

Showing 1–10 of 629

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.

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Clinical & Coding Specifications

Clinical Context

Typical workflow:

The patient is evaluated in the outpatient wound clinic, emergency department, or operating room for a complex wound.
The primary procedure (for example, debridement, excision, or graft placement) is performed and documented with the appropriate CPT code(s).
The wound is measured and the provider documents the number of square centimeters of matrix applied.
The Rampart dl matrix is applied and secured according to manufacturer instructions; documentation includes product name, lot number, quantity (cm2), and clinical rationale.
Billing is submitted with the primary procedure CPT code(s) and the add-on HCPCS Level II code Q4347 with the appropriate modifier(s) to reflect circumstances of service or payer requirements.

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`11042`	Debridement, subcutaneous tissue (includes epidermis and dermis), first 20 sq cm or less	Commonly billed when surgical debridement precedes placement of the extracellular matrix to prepare the wound bed.
`11043`	Debridement, muscle and/or fascia, first 20 sq cm or less	Used for deeper debridement of wounds prior to matrix application when muscle or fascia are involved.
`15271`	Application of biologic (eg, collagen) graft to trunk, arms, legs; first 100 sq cm or less, or peripheral vascular bypass wound of lower extremity	May be used for primary reporting of biologic graft application; `Q4347` is billed additionally per square centimeter for the specific Rampart dl matrix as an add-on product.
`15275`	Application of skin substitute graft resulting in full-thickness skin loss, trunk, arms, legs; greater than 100 sq cm	Performed when larger surface areas require coverage; the matrix product may be used adjunctively and reported with `Q4347`.
`15734`	Muscle, myocutaneous, or fasciocutaneous flap with microvascular anastomosis	Performed for complex reconstruction; biologic matrix may be used adjunctively to support soft tissue coverage and reported as add-on if applicable.

Related Modifiers

6 rows

Modifier	Description	When to Use
22	Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…	- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
23	Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…	- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
52	Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…	- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
53	Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…	- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
62	Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…	- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
78	CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…	- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…

Related Provider Taxonomies

8 rows

Taxonomy Code	Specialty	Notes
174400000X	Specialist	An individual educated and trained in an applied knowledge discipline used in the performance of work at a level requiring knowledge and skills beyond…
207Q00000X	Family Medicine Physician	Family Medicine is the medical specialty which is concerned with the total health care of the individual and the family. It is the specialty in breadt…
363A00000X	Physician Assistant	A physician assistant is a person who has successfully completed an accredited education program for physician assistant, is licensed by the state and…
103T00000X	Psychologist	A psychologist is an individual who is licensed to practice psychology which is defined as the observation, description, evaluation, interpretation, a…
225XR0403X	Driving and Community Mobility Occupational Therapist	Occupational therapists can optimize and prolong an older driver's ability to drive safely and ease the transition to other forms of transportation if…
3336L0003X	Long Term Care Pharmacy	A pharmacy that dispenses medicinal preparations delivered to patients residing within an intermediate or skilled nursing facility, including intermed…
163WI0500X	Infusion Therapy Registered Nurse	Nursing Service Providers · Registered Nurse
2084P0301X	Brain Injury Medicine (Psychiatry & Neurology) Physician	A Brain Injury Medicine physician specializes in disorders of brain function due to injury and disease. These disorders encompass a range of medical,…

Related ICD-10-CM Codes

23 rows

ICD-10-CM Code	Description
E10.621	Type 1 diabetes mellitus with foot ulcer
E11.621	Type 2 diabetes mellitus with foot ulcer
I83.013	Varicose veins of right lower extremity with ulcer of ankle
I83.219	Varicose veins of right lower extremity with both ulcer of unspecified site and inflammation
I87.2	Venous insufficiency (chronic) (peripheral)
L03.115	Cellulitis of right lower limb
L03.116	Cellulitis of left lower limb
L89.151	Pressure ulcer of sacral region, stage 1
L89.152	Pressure ulcer of sacral region, stage 2
L89.153	Pressure ulcer of sacral region, stage 3

Showing 1–10 of 23

Related Payer Policy Updates

Specialty: Infectious Disease1 / 3

10 rows

Policy	Payer	Effective Date
B-Hemolytic Streptococcus Testing	Oscar Health	2026-10-01
Human Immunodeficiency Virus (HIV) — Coverage Criteria for Testing and Resistance Assays	Oscar Health	2026-10-01
Hepatitis Testing (A, B, C, D) Coverage Criteria	Oscar Health	2026-10-01
Lyme Disease Testing Coverage Criteria	Oscar Health	2026-10-01
Pathogen Panel Testing	Oscar Health	2026-10-01
Diagnostic Testing of Common Sexually Transmitted Infections	Oscar Health	2026-10-01
Coronavirus Testing in the Outpatient Setting	Oscar Health	2026-10-01
Testing for Vector-Borne Infections	Oscar Health	2026-10-01
Testing for Diagnosis of Active or Latent Tuberculosis	Oscar Health	2026-10-01
Human Immunodeficiency Virus (HIV)	blue cross blue shield - louisiana	2026-09-15

HCPCS Q4139: Amniomatrix or Biodmatrix, Injectable, 1 cc

HCPCS-LEVEL-II-Q4256-AREA-BASED-PROCEDURAL-ADD-ON-PER-SQ-CM

HCPCS Q4256: MLG-complete Skin Graft Material, Per Sq Cm

HCPCS-LEVEL-II-Q5132-ADALIMUMAB-AFZB-ABRILADA-10MG-INJECTION

HCPCS Level II Q5132: Injection, adalimumab-afzb (Abrilada), 10 mg

HCPCS-Q0035-CARDIOKYMOGRAPHY-CARDIAC-MOTION-RECORDING

HCPCS Level II Q0035: Cardiokymography

HCPCS-Q0081-INFUSION-THERAPY-NON-CHEMOTHERAPEUTIC-PER-VISIT

HCPCS Level II Q0081: Infusion Therapy, Non‑Chemotherapeutic, Per Visit

HCPCS-Q0083-CHEMOTHERAPY-NON-INFUSION-ADMINISTRATION

HCPCS Q0083: Chemotherapy Administration, Non-Infusion Methods

HCPCS-Q0084-CHEMOTHERAPY-INFUSION-ADMINISTRATION-PER-VISIT

HCPCS Q0084: Chemotherapy Infusion Administration, Per Visit

HCPCS-Q0085-CHEMOTHERAPY-INFUSION-PLUS-OTHER-TECHNIQUES-PER-VISIT

HCPCS Q0085: Chemotherapy Infusion Plus Other Technique(s), Per Visit

HCPCS-Q0091-PAP-SMEAR-SPECIMEN-COLLECTION-TRANSPORT

HCPCS Q0091: Screening Papanicolaou Smear Collection and Transport

HCPCS-Q0092-PORTABLE-XRAY-EQUIPMENT-SETUP

HCPCS Q0092: Set-up Portable X-ray Equipment

Showing 1–10 of 629

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

OpenPayer

HCPCS Q4347: Rampart dl Matrix, Per Square Centimeter

Sign up for hcpcs Q4347 policy alerts

OpenPayer

HCPCS Q4347: Rampart dl Matrix, Per Square Centimeter

Sign up for hcpcs Q4347 policy alerts

Clinical & Coding Specifications

Clinical Context

Related CPT Codes

Related Modifiers

Related Provider Taxonomies

Related ICD-10-CM Codes

Related Payer Policy Updates

Related Codes

References

Clinical & Coding Specifications

Clinical Context

Related CPT Codes

Related Modifiers

Related Provider Taxonomies

Related ICD-10-CM Codes

Related Payer Policy Updates

Related Codes

References

HCPCS Q4347: Rampart dl Matrix, Per Square Centimeter

Sign up for hcpcs Q4347 policy alerts

HCPCS Q4347: Rampart dl Matrix, Per Square Centimeter

Sign up for hcpcs Q4347 policy alerts

Clinical & Coding Specifications

Clinical Context

Related CPT Codes

Related Modifiers

Related Provider Taxonomies

Related ICD-10-CM Codes

Related Payer Policy Updates

Related Codes

What does HCPCS code Q4347 represent and how is it reported?

What documentation is required when billing Q4347?

Do I bill Q4347 alone or with other procedure codes?

Which modifiers are commonly used with Q4347?

In which clinical situations and specialties is Q4347 most commonly used?

References

Clinical & Coding Specifications

Clinical Context

Related CPT Codes

Related Modifiers

Related Provider Taxonomies

Related ICD-10-CM Codes

Related Payer Policy Updates

Related Codes

What does HCPCS code Q4347 represent and how is it reported?

What documentation is required when billing Q4347?

Do I bill Q4347 alone or with other procedure codes?

Which modifiers are commonly used with Q4347?

In which clinical situations and specialties is Q4347 most commonly used?

References