Summary & Overview
HCPCS Level II Q4152: Dermapure, Per Square Centimeter (Add-on)
HCPCS Level II code Q4152 designates Dermapure billed per square centimeter as an add-on to a primary dermatologic procedure. The code captures surface-area–based reporting for adjunctive topical or local therapy used during dermatologic interventions and matters nationally because it affects procedure-level reimbursement, coding accuracy, and commodity tracking for skin-directed therapies. Payers commonly referenced for coverage and coding practices include Aetna, Blue Cross Blue Shield, Cigna, UnitedHealthcare, and Medicare.
This publication provides a concise national overview of HCPCS Level II code Q4152, explaining its clinical context and billing role, and outlines what readers can expect: a summary of payer coverage considerations, common modifiers and claims practices, and the clinical scenarios in which Dermapure is reported as an add-on per square centimeter. It highlights implications for documentation and claim construction and points readers to where to find policy language and coding guidance. Data not available in the input is noted where applicable.
Billing Code Overview
HCPCS Level II code Q4152 represents Dermapure, per square centimeter (add-on, list separately in addition to primary procedure). This code is used to report the application or administration of Dermapure measured by surface area in square centimeters when billed as an add-on to a primary dermatologic procedure.
Service type: Topical or local dermatologic therapy applied per square centimeter as an add-on to a primary skin procedure.
Typical site of service: Outpatient dermatology clinics, ambulatory surgical centers, or office-based dermatology procedures where a primary procedure is performed and Dermapure is applied as an adjunctive treatment.
Data not available in the input.
Clinical & Coding Specifications
Clinical Context
A typical patient is an adult seeking in-office dermatologic treatment for localized skin imperfections such as acne scarring, superficial rhytids, or focal dermal defects where a platelet-rich plasma or topical biologic adjunct (branded as Dermapure) is applied per square centimeter as an add-on to a primary procedural service. The clinical workflow begins with an evaluation by a dermatology or cosmetic surgery provider, documentation of the target treatment area size in square centimeters, informed consent for the primary procedure and the adjunct product, and billing of the primary procedure CPT code with the add-on HCPCS Level II code Q4152 reported per square centimeter. The typical site of service is an outpatient dermatology clinic, ambulatory surgical center, or physician office procedure room. The patient presentation often includes localized scarring, post-procedure skin irregularity, or aesthetic concerns where an adjunct topical/dermal product is applied to enhance outcomes; the provider documents medical necessity, quantity of product in square centimeters, and any applicable modifiers to reflect unusual circumstances such as increased procedural services, reduced services, or professional component billing separation.
Coding Specifications
| Modifier | Description | When to Use |
|---|---|---|
22 | Increased Procedural Services | Use when services are substantially greater than typical for the primary procedure when Dermapure application required significantly more work. |