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    v1.0.28
    OpenPayerBilling CodesDrugs Administered Other than Oral MethodHCPCS hcpcs-j7620-albuterol-ipratropium-nebulized-dme
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    HCPCS Level II J7620: Albuterol and Ipratropium Nebulized DME Product

    HCPCS Level II code J7620 describes an FDA-approved combination drug product of albuterol (up to 2.5 mg) and ipratropium bromide (up to 0.5 mg) supplied as a final, non-compounded solution for administration through durable medical equipment; the service is a respiratory medication administration delivered via nebulizer and the typical site of service is outpatient or home using DME nebulizer equipment.

    For related coverage guidance, see recent payer policy updates: Epithelial Cell Cytology in Breast Cancer Risk Assessment, Chemotherapy Observation or Inpatient Hospitalization (for New Mexico Only), Antibody-Drug Conjugates.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is an adult or pediatric individual presenting to an outpatient infusion clinic, emergency department, or skilled nursing facility with acute exacerbation of chronic obstructive pulmonary disease (COPD) or an acute asthma exacerbation with bronchospasm unresponsive to handheld inhalers. The patient is assessed by a clinician (pulmonologist, emergency physician, or respiratory therapist). Vitals and pulse oximetry are monitored. A decision is made to administer nebulized combination therapy of albuterol and ipratropium bromide using durable medical equipment (nebulizer supplied by a DME vendor). The medication billed with J7620 is the FDA-approved premixed albuterol up to 2.5 mg with ipratropium bromide up to 0.5 mg solution, non-compounded, delivered via the facility’s or patient’s DME nebulizer. Typical workflow: evaluate airway/breathing, document indication and response, set up nebulizer with the J7620 ampule or single-use vial, administer over standard treatment time (typically 5–15 minutes), monitor for improvement or adverse effects (tachycardia, tremor, dry mouth), document start/stop times, and disposition (return to baseline, observation, admission, or discharge). Billing may occur for each unit of drug administered per facility policy and payer rules; modifiers may be appended as appropriate for place of service, provider status, or service circumstances.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    94640Pressurized or non-pressurized inhalation treatment for acute airway obstruction or for sputum induction, including aerosol generator, nebulizer, tubing, and mask or mouthpieceFrequently billed when a nebulized bronchodilator combination is administered and facility or provider bills for the inhalation treatment service in addition to the drug.
    99283Emergency department visit, moderate severityCommon E/M code for an ED encounter where nebulized J7620 therapy is initiated for an acute exacerbation.
    94664Demonstration and/or evaluation of patient utilization of an aerosol generator, nebulizer, metered dose inhaler, or IPPB devicePerformed when patient education or device training accompanies nebulized therapy, often in outpatient or home DME settings.
    36415Collection of venous blood by venipunctureOften performed alongside acute respiratory treatment to obtain labs (e.g., arterial blood gas or basic labs) in the ED or inpatient setting.
    94010Breathing capacity test (spirometry)Performed in outpatient follow-up to assess response to bronchodilator therapy and evaluate airway obstruction.

    Related Modifiers

    6 rows

    ModifierDescriptionWhen to Use
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    25CPT modifier 25 indicates that on the same day as another procedure or service, the same physician or other qualified health care professional provided a significant, separately identifiable…- When to apply: Use modifier 25 only on an E/M code to indicate the same provider delivered a significant, separately identifiable E/M service on the same day as another procedure or service — i.e.,…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    77Modifier 77 indicates that a previously performed procedure or service was legitimately repeated by a different physician or other qualified health care professional. The AMA’s CPT definition…- Use modifier 77 when a basic procedure or service already performed is repeated by a different physician or other qualified health care professional (for example, a second provider independently…

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    207RH0000XHematology (Internal Medicine) PhysicianAn internist with additional training who specializes in diseases of the blood, spleen and lymph. This specialist treats conditions such as anemia, cl…
    207RR0500XRheumatology PhysicianAn internist who treats diseases of joints, muscle, bones and tendons. This specialist diagnoses and treats arthritis, back pain, muscle strains, comm…
    261QP2300XPrimary Care Clinic/CenterAmbulatory Health Care Facilities · Clinic/Center
    261QX0200XOncology Clinic/CenterAn entity, facility, or distinct part of a facility providing diagnostic, treatment and prescriptive services related to cancerous conditions. Servic…
    315D00000XInpatient HospiceA provider organization, or distinct part of the organization, which renders an interdisciplinary program providing palliative care, chiefly medical r…
    251F00000XHome Infusion AgencyAgencies · Home Infusion
    163WH0200XHome Health Registered NurseNursing Service Providers · Registered Nurse
    364SH0200XHome Health Clinical Nurse SpecialistPhysician Assistants & Advanced Practice Nursing Providers · Clinical Nurse Specialist

    Related ICD-10-CM Codes

    29 rows

    ICD-10-CM CodeDescription
    E66.9Obesity, unspecified
    I27.21Secondary pulmonary arterial hypertension
    I50.1Left ventricular failure, unspecified
    I50.9Heart failure, unspecified
    J10.1Influenza due to other identified influenza virus with other respiratory manifestations
    J11.1Influenza due to unidentified influenza virus with other respiratory manifestations
    J12.9Viral pneumonia, unspecified
    J13Pneumonia due to Streptococcus pneumoniae
    J18.9Pneumonia, unspecified organism
    J20.9Acute bronchitis, unspecified

    Showing 1–10 of 29

    Related Payer Policy Updates

    Specialty: Hematology/Oncology1 / 3

    4 rows

    PolicyPayerEffective Date
    Epithelial Cell Cytology in Breast Cancer Risk AssessmentOscar Health2026-10-01
    Chemotherapy Observation or Inpatient Hospitalization (for New Mexico Only)UnitedHealthcare2026-08-01
    Antibody-Drug ConjugatesPremera Bluecross2026-08-01
    Umbilical Cord Blood Harvesting and Storage for Future Use (for Indiana Only)UnitedHealthcare2026-08-01

    Related Codes

    HCPCS-J0013-ESKETAMINE-NASAL-SPRAY-1MG

    HCPCS Level II J0013: Esketamine Nasal Spray, 1 mg

    HCPCS-J0120-INJECTION-TETRACYCLINE-250MG

    HCPCS Level II J0120: Injection, Tetracycline, up to 250 mg

    HCPCS-J0121-OMADACYCLINE-INJECTION-1MG

    HCPCS Level II J0121: Omadacycline Injection, 1 mg

    HCPCS-J0122-ERAVACYCLINE-INJECTION-1MG

    HCPCS Level II J0122: Injection, eravacycline, 1 mg

    HCPCS-J0129-ABATACEPT-INJECTION-10MG-PHYSICIAN-SUPERVISED

    HCPCS Level II J0129: Abatacept Injection, 10 mg

    HCPCS-J0130-INJECTION-ABCIXIMAB-10MG

    HCPCS Level II J0130: Injection abciximab, 10 mg

    HCPCS-J0131-INJECTION-ACETAMINOPHEN-10MG-PARENTERAL-ANALGESIC

    HCPCS Level II J0131: Injection, Acetaminophen 10 mg

    HCPCS-J0132-INJECTION-ACETYLCYSTEINE-100MG-INJECTABLE-MEDICATION

    HCPCS Level II J0132: Injection, Acetylcysteine 100 mg

    HCPCS-J0133-ACYCLOVIR-INJECTION-5MG

    HCPCS Level II J0133: Injection, Acyclovir 5 mg

    HCPCS-J0134-ACETAMINOPHEN-INJECTION-FRESENIUS-KABI-10MG

    HCPCS Level II J0134: Injection, Acetaminophen (10 mg)

    Showing 1–10 of 991

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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