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    v1.0.31
    OpenPayerBilling CodesDrugs Administered Other than Oral MethodHCPCS hcpcs-j7297-levonorgestrel-iud-liletta-52mg
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    HCPCS Level II J7297: Levonorgestrel IUD (Liletta) 52 mg

    HCPCS Level II code J7297 describes the levonorgestrel-releasing intrauterine contraceptive system (Liletta), 52 mg, a long-acting reversible contraceptive device supplied for intrauterine placement; service type is device supply for intrauterine contraception and the typical site of service is an outpatient ambulatory clinic or office where IUD placement and device provisioning occur.

    For related coverage guidance, see recent payer policy updates: Bendamustine Products Coverage Criteria, T-Cell Lymphoma Agents: Beleodaq, Istodax, Lymphir, Poteligeo, and Romidepsin, Brentuximab Vedotin (Adcetris®) Coverage Criteria.

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    Clinical & Coding Specifications

    Clinical Context

    A 28-year-old person presents to an ambulatory gynecology clinic requesting long-acting reversible contraception. They have completed counseling about options and select a levonorgestrel-releasing intrauterine system (Liletta, J7297, 52 mg). The patient has a negative pregnancy test and no active pelvic infection. The clinical workflow includes pre-procedure counseling and consent, pregnancy testing, review of cervical infection risk and recent STI screen as indicated, pelvic exam and bimanual exam, placement of the intrauterine device under speculum visualization with sterile technique, post-placement instructions, and scheduling of a follow-up visit (commonly 4–12 weeks) to check threads and address concerns. Typical site of service is an outpatient physician office or ambulatory surgery center. The service type is a contraceptive device insertion and supply of the medication-eluting intrauterine contraceptive system. Common patient scenarios include routine contraception initiation, replacement at end of labeled duration, or replacement for heavy menstrual bleeding management when appropriate.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    58300Insertion of intrauterine device (IUD)Primary procedure for placement of an intrauterine contraceptive device; performed at the time J7297 supply when billing separate insertion service.
    58301Removal of intrauterine device (IUD)Performed when the existing device is removed prior to replacement with J7297 or for device removal for other reasons.
    58301 + 58300 comboRemoval with reinsertion during same encounter (report both codes where supported)Common workflow when an existing IUD is removed and a new J7297 device is inserted in the same visit.
    99213Office or other outpatient visit for established patient, moderate complexityTypical E/M code when counseling, consent, and evaluation occur on the same day as device insertion; use 25 modifier when appropriate.
    99070Supplies and materials (eg, non-implantable)Sometimes used by facilities to report additional supply costs; check payer rules regarding device supply reporting.

    Related Modifiers

    7 rows

    ModifierDescriptionWhen to Use
    25CPT modifier 25 indicates that on the same day as another procedure or service, the same physician or other qualified health care professional provided a significant, separately identifiable…- When to apply: Use modifier 25 only on an E/M code to indicate the same provider delivered a significant, separately identifiable E/M service on the same day as another procedure or service — i.e.,…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207Q00000X
    208000000X
    363L00000X
    207V00000X
    163WP1700X
    103TC0700X
    376K00000X
    364SN0000X

    Related ICD-10-CM Codes

    25 rows

    ICD-10-CM CodeDescription
    N76.0Acute vaginitis
    N76.1Subacute and chronic vaginitis
    N76.2Acute vulvitis
    N80.9Endometriosis, unspecified
    N91.0Primary amenorrhea
    N91.4Secondary oligomenorrhea
    N92.0Excessive and frequent menstruation with regular cycle
    N92.1Excessive and frequent menstruation with irregular cycle
    N92.4Excessive bleeding in the premenopausal period
    N93.9Abnormal uterine and vaginal bleeding, unspecified

    Showing 1–10 of 25

    Related Payer Policy Updates

    Specialty: Hematology/Oncology1 / 3

    10 rows

    PolicyPayerEffective Date
    Bendamustine Products Coverage Criteriablue cross blue shield - tennessee2027-01-30
    T-Cell Lymphoma Agents: Beleodaq, Istodax, Lymphir, Poteligeo, and RomidepsinMass General Brigham Health Plan2027-01-04
    Brentuximab Vedotin (Adcetris®) Coverage Criteriablue cross blue shield - tennessee2026-12-31
    Pemetrexed Coverageblue cross blue shield - tennessee2026-12-31
    Tumor Treatment Fields - Medical PolicyHealth-New-England2026-12-01
    Extracorporeal PhotopheresisCigna2026-11-15
    VonvendiCigna2026-11-15
    Hematology - AphexdaCigna2026-11-15
    Extracorporeal PhotopheresisCigna2026-11-15
    Yartemlea (narsoplimab-wuug) Coverage for TA-TMANeighborhood Health Plan of Rhode Island2026-11-01

    Related Codes

    HCPCS-J0013-ESKETAMINE-NASAL-SPRAY-1MG

    HCPCS Level II J0013: Esketamine Nasal Spray, 1 mg

    HCPCS-J0120-INJECTION-TETRACYCLINE-250MG

    HCPCS Level II J0120: Injection, Tetracycline, up to 250 mg

    HCPCS-J0121-OMADACYCLINE-INJECTION-1MG

    HCPCS Level II J0121: Omadacycline Injection, 1 mg

    HCPCS-J0122-ERAVACYCLINE-INJECTION-1MG

    HCPCS Level II J0122: Injection, eravacycline, 1 mg

    HCPCS-J0129-ABATACEPT-INJECTION-10MG-PHYSICIAN-SUPERVISED

    HCPCS Level II J0129: Abatacept Injection, 10 mg

    HCPCS-J0130-INJECTION-ABCIXIMAB-10MG

    HCPCS Level II J0130: Injection abciximab, 10 mg

    HCPCS-J0131-INJECTION-ACETAMINOPHEN-10MG-PARENTERAL-ANALGESIC

    HCPCS Level II J0131: Injection, Acetaminophen 10 mg

    HCPCS-J0132-INJECTION-ACETYLCYSTEINE-100MG-INJECTABLE-MEDICATION

    HCPCS Level II J0132: Injection, Acetylcysteine 100 mg

    HCPCS-J0133-ACYCLOVIR-INJECTION-5MG

    HCPCS Level II J0133: Injection, Acyclovir 5 mg

    HCPCS-J0134-ACETAMINOPHEN-INJECTION-FRESENIUS-KABI-10MG

    HCPCS Level II J0134: Injection, Acetaminophen (10 mg)

    Showing 1–10 of 991

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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