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    v1.0.28
    OpenPayerBilling CodesDrugs Administered Other than Oral MethodHCPCS hcpcs-j1444-ferric-pyrophosphate-citrate-injection-iron-0-1-mg
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    HCPCS Level II J1444: Ferric Pyrophosphate Citrate Injection, 0.1 mg

    HCPCS Level II code J1444 describes a billing entry for an injection of ferric pyrophosphate citrate powder containing 0.1 mg of iron, used as an intravenous iron replacement therapy preparation; the service is the administration of an iron formulation supplied as a powder for injection and the typical site of service is an outpatient infusion or dialysis setting where IV iron is administered.

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    Clinical & Coding Specifications

    Clinical Context

    A 54-year-old patient with end-stage renal disease (ESRD) on maintenance hemodialysis presents for routine in-center dialysis. The patient has documented iron deficiency related to ongoing blood losses and inflammatory-mediated functional iron deficiency despite prior oral iron therapy. The clinician orders intravenous administration of ferric pyrophosphate citrate to maintain hemoglobin and reduce erythropoiesis-stimulating agent requirements. The product described by billing code J1444 (injection, ferric pyrophosphate citrate powder, 0.1 mg of iron) is prepared per manufacturer instructions and administered via the dialysis circuit during each hemodialysis session by a dialysis nurse under standing order or direct provider authorization. Vital signs are monitored before, during, and after infusion; the dialysis nursing note documents lot number, dose, route (via dialysis catheter/arterial line), and any adverse reactions. Billing is submitted under the outpatient dialysis encounter with J1444 reported per 0.1 mg dosing units as applicable, and appropriate place-of-service and modifier usage recorded when required.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    90935Hemodialysis procedure with single evaluation by a physician or other qualified health care professionalRepresents a dialysis session during which J1444 may be administered; documents the dialysis treatment encounter.
    96365Intravenous infusion, for therapy, prophylaxis, or diagnosis; initial, up to 1 hourUsed when an infusion service is separately reportable for IV medications administered during a dialysis session if payer allows.
    96374Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); intramuscularUsed rarely if formulation/administration route differs; typically not used for dialysis circuit administration.
    36415Collection of venous blood by venipuncturePerformed when pre- and post-dialysis labs (iron studies, hemoglobin) are drawn to monitor therapy effectiveness.
    84148FerritinLaboratory test commonly ordered to assess iron stores prior to or during therapy with J1444.
    85014Hemoglobin; quantitative, automatedRoutine lab monitoring related to iron therapy response during dialysis care.

    Related Modifiers

    9 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    54Modifier ‑54 (“Surgical care only”) is appended to a CPT surgical procedure when the reporting surgeon performs the intraoperative (surgical) component but does not furnish the preoperative and/or…- Use modifier -54 when the reporting surgeon provided only the intraoperative (surgical) component of a procedure and preoperative and/or postoperative management has been or will be provided by…
    55Modifier –55 indicates the billing provider furnished only postoperative management for a procedure that has a global surgical period. According to AAPC, this modifier is appended to the same CPT…- Use modifier -55 when billing the same CPT surgical code that has a 10- or 90-day global period and you, as a provider other than the original surgeon, furnished ONLY postoperative management (no…
    56Modifier ‑56 indicates the reporting provider furnished only the preoperative management for a surgical procedure and did not perform the intraoperative or postoperative care. It is used in…- Use Modifier -56 when a provider performs only the preoperative management in a split‑care situation (one physician manages preop care while a different physician performs the intraoperative…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    174M00000XVeterinarianA doctor of veterinary medicine, trained and authorized to practice veterinarian medicine and surgery.
    363A00000XPhysician AssistantA physician assistant is a person who has successfully completed an accredited education program for physician assistant, is licensed by the state and…
    363L00000XNurse Practitioner(1) A registered nurse provider with a graduate degree in nursing prepared for advanced practice involving independent and interdependent decision mak…
    363LA2200XAdult Health Nurse PractitionerPhysician Assistants & Advanced Practice Nursing Providers · Nurse Practitioner
    171R00000XInterpreterAn Interpreter is a person who translates oral communication between two or more people. This includes translating from one language to another or in…
    1223G0001XGeneral Practice DentistryA general dentist is the primary dental care provider for patients of all ages. The general dentist is responsible for the diagnosis, treatment, manag…
    261QE0700XEnd-Stage Renal Disease (ESRD) Treatment Clinic/CenterAmbulatory Health Care Facilities · Clinic/Center
    163WC3500XCardiac Rehabilitation Registered NurseNursing Service Providers · Registered Nurse

    Related ICD-10-CM Codes

    27 rows

    ICD-10-CM CodeDescription
    B20Human immunodeficiency virus [HIV] disease
    C18.9Malignant neoplasm of colon, unspecified
    C22.0Liver cell carcinoma
    C34.90Malignant neoplasm of unspecified part of unspecified bronchus or lung
    C50.912Malignant neoplasm of unspecified site of left female breast
    D46.9Myelodysplastic syndrome, unspecified
    D50.0Iron deficiency anemia secondary to blood loss (chronic)
    D50.8Other iron deficiency anemias
    D50.9Iron deficiency anemia, unspecified
    D63.0Anemia in neoplastic disease

    Showing 1–10 of 27

    Related Codes

    HCPCS-J0013-ESKETAMINE-NASAL-SPRAY-1MG

    HCPCS Level II J0013: Esketamine Nasal Spray, 1 mg

    HCPCS-J0120-INJECTION-TETRACYCLINE-250MG

    HCPCS Level II J0120: Injection, Tetracycline, up to 250 mg

    HCPCS-J0121-OMADACYCLINE-INJECTION-1MG

    HCPCS Level II J0121: Omadacycline Injection, 1 mg

    HCPCS-J0122-ERAVACYCLINE-INJECTION-1MG

    HCPCS Level II J0122: Injection, eravacycline, 1 mg

    HCPCS-J0129-ABATACEPT-INJECTION-10MG-PHYSICIAN-SUPERVISED

    HCPCS Level II J0129: Abatacept Injection, 10 mg

    HCPCS-J0130-INJECTION-ABCIXIMAB-10MG

    HCPCS Level II J0130: Injection abciximab, 10 mg

    HCPCS-J0131-INJECTION-ACETAMINOPHEN-10MG-PARENTERAL-ANALGESIC

    HCPCS Level II J0131: Injection, Acetaminophen 10 mg

    HCPCS-J0132-INJECTION-ACETYLCYSTEINE-100MG-INJECTABLE-MEDICATION

    HCPCS Level II J0132: Injection, Acetylcysteine 100 mg

    HCPCS-J0133-ACYCLOVIR-INJECTION-5MG

    HCPCS Level II J0133: Injection, Acyclovir 5 mg

    HCPCS-J0134-ACETAMINOPHEN-INJECTION-FRESENIUS-KABI-10MG

    HCPCS Level II J0134: Injection, Acetaminophen (10 mg)

    Showing 1–10 of 991

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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