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HCPCS G0680: Coronary Artery and Aortic Valve Calcification Quantification

HCPCS Level II code G0680 identifies an algorithmic analysis and reporting service that detects and quantifies coronary artery calcium and/or aortic valve calcification from computed tomography of the chest. As automated and semi-automated calcium scoring tools proliferate, this code captures a distinct imaging-derived quantification service separate from CT acquisition and primary radiology interpretation. Nationally, the code matters for cardiac risk stratification workflows, preventive cardiology pathways, and reimbursement clarity around post-processing imaging analytics.

Key payers in the analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. The publication outlines payer coverage patterns and benchmark considerations where available, though specific coverage details may vary by plan and clinical indication.

Readers will learn the clinical context for use of G0680, typical service venues, and the role of algorithmic calcium quantification in care pathways. The report also summarizes where stakeholders commonly look for benchmarks, coding relationships, and policy updates relevant to imaging post-processing codes. Data not available in the input are explicitly noted in relevant sections.

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Billing Code Overview

HCPCS Level II code G0680 describes the detection and quantification of coronary artery calcium and/or aortic valve calcification using algorithmic analysis of computed tomography of the chest, with an accompanying report. This service represents an image-processing and interpretation workflow that derives quantitative calcium scores from chest CT data.

Service type: Algorithmic analysis and reporting of chest CT imaging for vascular and valvular calcification quantification
Typical site of service: Outpatient radiology or diagnostic imaging centers, hospital radiology departments, and any setting where chest CT studies are acquired and processed for secondary quantitative analysis

Data not available in the input for modifiers, associated taxonomies, ICD-10 diagnoses, related codes, and service line.

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HCPCS G0680: Coronary Artery and Aortic Valve Calcification Quantification

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Get alerted when payer policies referencing G0680 are released or updated.

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Billing Code Overview

Service type: Algorithmic analysis and reporting of chest CT imaging for vascular and valvular calcification quantification
Typical site of service: Outpatient radiology or diagnostic imaging centers, hospital radiology departments, and any setting where chest CT studies are acquired and processed for secondary quantitative analysis

Data not available in the input for modifiers, associated taxonomies, ICD-10 diagnoses, related codes, and service line.

Clinical & Coding Specifications

Clinical Context

A 62-year-old asymptomatic man with intermediate cardiovascular risk due to hypertension and hyperlipidemia is referred for coronary artery calcium (CAC) scoring using non-contrast computed tomography of the chest. The ordering clinician requests algorithmic detection and quantification of coronary artery calcium and aortic valve calcification with a structured report to inform primary prevention decisions. Workflow: scheduling and preauthorization (if required) → patient arrives and screening/consent → non-contrast chest CT acquisition using cardiac-gated or non-gated protocol per facility policy → image reconstruction and transfer to automated CAC quantification software (algorithmic analysis) → software generates Agatston score, lesion volumes, and aortic valve calcium metrics → interpreting physician reviews automated results, edits if necessary, and finalizes a structured report that includes total and vessel-specific CAC, Agatston score categories, and aortic valve calcification findings → report is transmitted to the ordering clinician for risk stratification and management planning. Typical site of service: outpatient radiology or cardiology imaging suite within an ambulatory care center, hospital outpatient department, or imaging center.

Coding Specifications

Modifier	Description	When to Use
`26`	Professional component	When billing the physician interpretation of the algorithm-generated CAC/aortic valve calcification report separately from technical imaging services.
`TC`	Technical component	When billing only the imaging acquisition and algorithm processing, without physician interpretation.
`59`	Distinct procedural service	When CAC scoring is performed in a separate session or distinct from another imaging procedure on the same day and documentation supports distinct service.
`GQ`	Telehealth originating site (as an example G modifier for services via asynchronous technology)	When algorithmic analysis and reporting occur using credentialed remote software workflow subject to payer-specific guidance.
`LT`	Left side	If a laterality modifier is required by a payer for aortic valve or left-sided-specific annotation (rare; use per payer rules).
`RT`	Right side	If a laterality modifier is required by a payer for right-sided-specific annotation (rare; use per payer rules).
`25`	Significant, separately identifiable evaluation and management service by the same physician on the same day	When an E/M visit is performed on the same day with documentation supporting a significant separate service in addition to interpretation and reporting.
`57`	Decision for surgery	When the visit leading to the imaging represents the initial decision for surgery and payer rules require this modifier (rare for CAC studies).
`GA`	Waiver of liability statement on file (patient requested ABN)	When the patient has signed an Advance Beneficiary Notice and the payer requires this modifier for beneficiary liability declarations.
`XE`	Separate encounter, distinct from the other service	When the algorithmic analysis is performed during a separate encounter per documentation and payer rules.

Taxonomy Code	Specialty	Notes
`207RC0000X`	Radiology — Diagnostic Radiology	Radiologists commonly interpret chest CT and finalize CAC/aortic valve calcification reports.
`2084P0800X`	Cardiology — Interventional Cardiology	Cardiologists may order and interpret CAC scoring as part of cardiovascular risk assessment and procedural planning.
`207L00000X`	Nuclear Medicine	Imaging specialists involved in cardiac imaging workflows and image quantification software oversight.
`207K00000X`	Radiology — Diagnostic Thoracic Radiology	Thoracic radiologists who interpret chest CTs and incidental cardiac/aortic valve calcifications.

Related Diagnoses

ICD-10 Code	Description	Clinical Relevance
`I25.10`	Atherosclerotic heart disease of native coronary artery without angina pectoris	CAC scoring quantifies coronary atherosclerotic calcified plaque burden to stratify risk in patients with suspected or known coronary artery disease.
`I10`	Essential (primary) hypertension	Hypertension is a common risk factor prompting CAC scoring for cardiovascular risk assessment.
`E78.5`	Hyperlipidemia, unspecified	Dyslipidemia contributes to atherosclerotic disease; CAC informs primary prevention decisions for lipid management.
`R07.9`	Chest pain, unspecified	Symptomatic patients with non-anginal chest pain may receive CAC scoring as part of evaluation in selected clinical pathways.
`Z13.6`	Encounter for screening for cardiovascular disorders	CAC scoring is frequently ordered as a screening or risk assessment tool in asymptomatic patients with risk factors.

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`71250`	CT chest without contrast material, single or multiple focal areas; standard reconstruction	Often the imaging acquisition code used when a non-contrast chest CT is performed for CAC scoring; provides the technical dataset for algorithmic analysis.
`75571`	Coronary artery calcium scoring by CT without contrast material, using 3D image processing; interpretation and reporting	Clinically specific CPT for CAC scoring—may be reported in workflows where facility and payers accept CPT coding for CAC instead of HCPCS Level II reporting.
`74177`	CT abdomen and pelvis; without contrast material	Occasionally performed in the same session for other indications; listed when multiple regional CTs are performed (documentation must support distinct services).
`93799`	Unlisted cardiovascular procedure (nonoperative)	Used rarely if specific algorithmic aortic valve calcium quantification lacks an exact CPT match and payer requires an unlisted code with supporting documentation.
`70450`	CT head/brain without contrast material	Included as a commonly performed unrelated CT that might be documented on the same day; not routine but listed for completeness when multiple imaging studies occur.

HCPCS G9490: Home Visit Assessment for Non-Homebound Patients

HCPCS-G0008-INFLUENZA-VACCINE-ADMINISTRATION

HCPCS G0008: Influenza Virus Vaccine Administration

HCPCS-G0009-PNEUMOCOCCAL-VACCINE-ADMINISTRATION

HCPCS G0009: Administration of Pneumococcal Vaccine

HCPCS-G0010-HEPATITIS-B-VACCINE-ADMINISTRATION

HCPCS G0010: Administration of Hepatitis B Vaccine

HCPCS-G0011-PREP-COUNSELING-HIV-RISK-REDUCTION-ADHERENCE

HCPCS G0011: Individual PrEP Counseling, HIV Risk Assessment

HCPCS-G0012-PRE-EXPOSURE-PROPHYLAXIS-INJECTION-HIV-PREVENTION

HCPCS G0012: Injection of Pre-Exposure Prophylaxis (PrEP) for HIV Prevention

HCPCS-G0013-PREP-INDIVIDUAL-COUNSELING-HIV-RISK-REDUCTION

HCPCS G0013: Individual PrEP Counseling and HIV Risk Assessment

HCPCS-G0017-PSYCHOTHERAPY-CRISIS-FIRST-60-MINUTES-NON-OFFICE

HCPCS G0017: Psychotherapy for Crisis, First 60 Minutes

HCPCS-G0018-PSYCHOTHERAPY-CRISIS-ADDITIONAL-30-MINUTES-NON-OFFICE

HCPCS G0018: Psychotherapy for Crisis, Additional 30 Minutes

HCPCS-G0019-COMMUNITY-HEALTH-INTEGRATION-SDOH-CARE-COORDINATION

HCPCS G0019: Community Health Integration for Social Determinants of Health

Showing 1–10 of 1996

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.

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Clinical & Coding Specifications

Clinical Context

Coding Specifications

Modifier	Description	When to Use
`26`	Professional component	When billing the physician interpretation of the algorithm-generated CAC/aortic valve calcification report separately from technical imaging services.
`TC`	Technical component	When billing only the imaging acquisition and algorithm processing, without physician interpretation.
`59`	Distinct procedural service	When CAC scoring is performed in a separate session or distinct from another imaging procedure on the same day and documentation supports distinct service.
`GQ`	Telehealth originating site (as an example G modifier for services via asynchronous technology)	When algorithmic analysis and reporting occur using credentialed remote software workflow subject to payer-specific guidance.
`LT`	Left side	If a laterality modifier is required by a payer for aortic valve or left-sided-specific annotation (rare; use per payer rules).
`RT`	Right side	If a laterality modifier is required by a payer for right-sided-specific annotation (rare; use per payer rules).
`25`	Significant, separately identifiable evaluation and management service by the same physician on the same day	When an E/M visit is performed on the same day with documentation supporting a significant separate service in addition to interpretation and reporting.
`57`	Decision for surgery	When the visit leading to the imaging represents the initial decision for surgery and payer rules require this modifier (rare for CAC studies).
`GA`	Waiver of liability statement on file (patient requested ABN)	When the patient has signed an Advance Beneficiary Notice and the payer requires this modifier for beneficiary liability declarations.
`XE`	Separate encounter, distinct from the other service	When the algorithmic analysis is performed during a separate encounter per documentation and payer rules.

Taxonomy Code	Specialty	Notes
`207RC0000X`	Radiology — Diagnostic Radiology	Radiologists commonly interpret chest CT and finalize CAC/aortic valve calcification reports.
`2084P0800X`	Cardiology — Interventional Cardiology	Cardiologists may order and interpret CAC scoring as part of cardiovascular risk assessment and procedural planning.
`207L00000X`	Nuclear Medicine	Imaging specialists involved in cardiac imaging workflows and image quantification software oversight.
`207K00000X`	Radiology — Diagnostic Thoracic Radiology	Thoracic radiologists who interpret chest CTs and incidental cardiac/aortic valve calcifications.

Related Diagnoses

ICD-10 Code	Description	Clinical Relevance
`I25.10`	Atherosclerotic heart disease of native coronary artery without angina pectoris	CAC scoring quantifies coronary atherosclerotic calcified plaque burden to stratify risk in patients with suspected or known coronary artery disease.
`I10`	Essential (primary) hypertension	Hypertension is a common risk factor prompting CAC scoring for cardiovascular risk assessment.
`E78.5`	Hyperlipidemia, unspecified	Dyslipidemia contributes to atherosclerotic disease; CAC informs primary prevention decisions for lipid management.
`R07.9`	Chest pain, unspecified	Symptomatic patients with non-anginal chest pain may receive CAC scoring as part of evaluation in selected clinical pathways.
`Z13.6`	Encounter for screening for cardiovascular disorders	CAC scoring is frequently ordered as a screening or risk assessment tool in asymptomatic patients with risk factors.

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`71250`	CT chest without contrast material, single or multiple focal areas; standard reconstruction	Often the imaging acquisition code used when a non-contrast chest CT is performed for CAC scoring; provides the technical dataset for algorithmic analysis.
`75571`	Coronary artery calcium scoring by CT without contrast material, using 3D image processing; interpretation and reporting	Clinically specific CPT for CAC scoring—may be reported in workflows where facility and payers accept CPT coding for CAC instead of HCPCS Level II reporting.
`74177`	CT abdomen and pelvis; without contrast material	Occasionally performed in the same session for other indications; listed when multiple regional CTs are performed (documentation must support distinct services).
`93799`	Unlisted cardiovascular procedure (nonoperative)	Used rarely if specific algorithmic aortic valve calcium quantification lacks an exact CPT match and payer requires an unlisted code with supporting documentation.
`70450`	CT head/brain without contrast material	Included as a commonly performed unrelated CT that might be documented on the same day; not routine but listed for completeness when multiple imaging studies occur.

HCPCS G9490: Home Visit Assessment for Non-Homebound Patients

HCPCS-G0008-INFLUENZA-VACCINE-ADMINISTRATION

HCPCS G0008: Influenza Virus Vaccine Administration

HCPCS-G0009-PNEUMOCOCCAL-VACCINE-ADMINISTRATION

HCPCS G0009: Administration of Pneumococcal Vaccine

HCPCS-G0010-HEPATITIS-B-VACCINE-ADMINISTRATION

HCPCS G0010: Administration of Hepatitis B Vaccine

HCPCS-G0011-PREP-COUNSELING-HIV-RISK-REDUCTION-ADHERENCE

HCPCS G0011: Individual PrEP Counseling, HIV Risk Assessment

HCPCS-G0012-PRE-EXPOSURE-PROPHYLAXIS-INJECTION-HIV-PREVENTION

HCPCS G0012: Injection of Pre-Exposure Prophylaxis (PrEP) for HIV Prevention

HCPCS-G0013-PREP-INDIVIDUAL-COUNSELING-HIV-RISK-REDUCTION

HCPCS G0013: Individual PrEP Counseling and HIV Risk Assessment

HCPCS-G0017-PSYCHOTHERAPY-CRISIS-FIRST-60-MINUTES-NON-OFFICE

HCPCS G0017: Psychotherapy for Crisis, First 60 Minutes

HCPCS-G0018-PSYCHOTHERAPY-CRISIS-ADDITIONAL-30-MINUTES-NON-OFFICE

HCPCS G0018: Psychotherapy for Crisis, Additional 30 Minutes

HCPCS-G0019-COMMUNITY-HEALTH-INTEGRATION-SDOH-CARE-COORDINATION

HCPCS G0019: Community Health Integration for Social Determinants of Health

Showing 1–10 of 1996

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

OpenPayer

HCPCS G0680: Coronary Artery and Aortic Valve Calcification Quantification

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Billing Code Overview

OpenPayer

HCPCS G0680: Coronary Artery and Aortic Valve Calcification Quantification

Sign up for hcpcs G0680 policy alerts

Billing Code Overview

Clinical & Coding Specifications

Clinical Context

Coding Specifications

Related Diagnoses

Related CPT Codes

Related Codes

References

Clinical & Coding Specifications

Clinical Context

Coding Specifications

Related Diagnoses

Related CPT Codes

Related Codes

References