HCPCS Level II code A9291 identifies an FDA-cleared, prescription digital therapeutic that delivers cognitive and/or behavioral therapy per course of treatment. As digital therapeutics expand, this code formalizes billing for prescribed software-based interventions that can be delivered in ambulatory or home settings and supports payer coverage and clinical adoption nationally.

Key payers in scope include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Coverage policies vary across commercial plans and Medicare; the presence of a distinct HCPCS Level II code facilitates policy development, prior authorization workflows, and claims processing.

Readers will find a concise overview of what the code represents, typical sites of service, and the clinical context for digital cognitive and behavioral treatment. The publication also covers payer coverage patterns, common modifiers used with the code, and implications for coding workflows and reimbursement administration. Where input data are incomplete, the report notes: "Data not available in the input." The goal is to clarify the purpose of A9291 and provide a practical reference for coding, billing, and policy teams navigating coverage of prescription digital therapeutics.