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    v1.0.28
    OpenPayerBilling CodesAdministrative, Miscellaneous and InvestigationalHCPCS hcpcs-a9555-rubidium-rb82-diagnostic-per-study-dose
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    HCPCS A9555: Rubidium Rb-82 Diagnostic Per-Study Dose

    HCPCS Level II code A9555 describes a diagnostic radiopharmaceutical service for Rubidium-82 (Rb-82) used in myocardial perfusion imaging, billed per study dose (up to 60 millicuries); the service typically represents administration of the Rb-82 tracer for cardiac PET imaging and is most often performed in an outpatient hospital imaging department or freestanding PET/ nuclear medicine facility for diagnostic evaluation of myocardial perfusion and viability.

    For related coverage guidance, see recent payer policy updates: Interferential Stimulation Devices (for home use), Prior Authorization for Durable Medical Equipment (DME), Breast Pumps.

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    Table of contents

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    • Billing CodesCPT, HCPCS, DRG & more
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    Clinical & Coding Specifications

    Clinical Context

    A 68-year-old patient with a history of ischemic heart disease and exertional chest pain is referred for myocardial perfusion imaging using rubidium-82 PET to evaluate for reversible myocardial ischemia. The clinical workflow begins with referral by a cardiologist or primary care physician, review of indications and contraindications, and verification of prior imaging and renal function. On the day of service the patient arrives to an outpatient nuclear medicine or PET/CT suite (typical site of service: hospital outpatient department or independent diagnostic testing facility). Intravenous access is obtained and baseline vital signs are recorded. A rest perfusion PET study may be performed first with administration of A9555 (rubidium rb-82, diagnostic, per study dose, up to 60 millicuries) followed by gated PET acquisition. If stress imaging is indicated, pharmacologic (regadenoson or adenosine) or exercise stress is performed and a second dose of A9555 is administered during peak stress with repeat gated perfusion acquisition. Image reconstruction, attenuation correction (often using low-dose CT), and quantitative perfusion analysis are performed by nuclear medicine physicians or cardiologists trained in cardiac PET. The professional component includes image interpretation and report generation; the technical component includes radiopharmaceutical supply, infusion system, PET scanner time, and technologist services. Relevant documentation includes indication, administered dose in mCi, lot and expiration for the radiopharmaceutical, stress protocol and agent, any adverse events, and the interpreting physician’s structured report with findings and impression.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    78459Myocardial perfusion imaging, PET, with pharmacologic stress or exercise, including interpretationCommon CPT code for PET myocardial perfusion studies paired with tracer administration A9555; covers imaging acquisition and interpretation when billed as a global PET study.
    78452Myocardial perfusion imaging, tomographic (SPECT) (list separately in contexts where SPECT is performed instead of PET)Alternative modality; included in workflow when comparing PET results to prior SPECT studies or when SPECT is used if PET unavailable.
    71010Radiologic exam, chest, single viewMay be performed as a pre-procedure chest radiograph in select patients to evaluate lines or devices prior to PET imaging.
    76700Ultrasound, abdominal aorta for aneurysm, screeningNot directly related; include only if concurrent vascular imaging is performed (rare).
    96365Intravenous infusion, therapeutic, prophylactic, diagnostic injectionMay be used for billing infusion of pharmacologic stress agents such as adenosine when administered separately from imaging codes.

    Related Modifiers

    9 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    77Modifier 77 indicates that a previously performed procedure or service was legitimately repeated by a different physician or other qualified health care professional. The AMA’s CPT definition…- Use modifier 77 when a basic procedure or service already performed is repeated by a different physician or other qualified health care professional (for example, a second provider independently…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    90Modifier ‑90 (Reference/Outside Laboratory) indicates that a laboratory test was performed by an entity other than the treating or reporting provider. The American Medical Association defines…- Use CPT modifier -90 when a laboratory test is performed by an outside/reference laboratory (an entity other than the treating or reporting physician or qualified professional) and the claim needs…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    82Modifier 82 is appended to a surgical CPT code to indicate that an attending physician acted as an assistant because a qualified resident surgeon was unavailable. In teaching hospitals it documents…- When to use: Append modifier 82 in teaching-hospital settings to indicate a physician served as an assistant surgeon because a qualified resident surgeon was unavailable (includes situations where…

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    207RC0000XCardiovascular Disease PhysicianAn internist who specializes in diseases of the heart and blood vessels and manages complex cardiac conditions such as heart attacks and life-threaten…
    208600000XSurgery PhysicianA general surgeon has expertise related to the diagnosis - preoperative, operative and postoperative management - and management of complications of s…
    363L00000XNurse Practitioner(1) A registered nurse provider with a graduate degree in nursing prepared for advanced practice involving independent and interdependent decision mak…
    163WX0106XOccupational Health Registered NurseNursing Service Providers · Registered Nurse
    146M00000XIntermediate Emergency Medical TechnicianAn Intermediate EMT is an individual trained and certified to perform intermediate life support treatment in medical emergencies based on individual s…
    207QA0000XAdolescent Medicine (Family Medicine) PhysicianA family medicine physician with multidisciplinary training in the unique physical, psychological and social characteristics of adolescents and their …
    273R00000XPsychiatric Hospital UnitIn general, a distinct unit of a hospital that provides acute or long-term care to emotionally disturbed patients, including patients admitted for dia…
    287300000XDeactivated - Christian Science SanitoriumInactive, use 282J00000X

    Related ICD-10-CM Codes

    27 rows

    ICD-10-CM CodeDescription
    E11.9Type 2 diabetes mellitus without complications
    E78.5Hyperlipidemia, unspecified
    I20.0Unstable angina
    I20.9Angina pectoris, unspecified
    I21.3ST elevation (STEMI) myocardial infarction of unspecified site
    I21.4Non-ST elevation (NSTEMI) myocardial infarction
    I21.9Acute myocardial infarction, unspecified
    I22.9Subsequent ST elevation (STEMI) myocardial infarction of unspecified site
    I25.10Atherosclerotic heart disease of native coronary artery without angina pectoris
    I25.110Atherosclerotic heart disease of native coronary artery with unstable angina pectoris

    Showing 1–10 of 27

    Related Payer Policy Updates

    Specialty: Durable Medical Equipment (DME)1 / 3

    10 rows

    PolicyPayerEffective Date
    Interferential Stimulation Devices (for home use)Moda Health2026-10-01
    Prior Authorization for Durable Medical Equipment (DME)Blue Cross Blue Shield - Rhode Island2026-10-01
    Breast PumpsModa Health2026-09-01
    Personal Emergency Response SystemsCareSource Georgia2026-09-01
    Continuous Passive Motion (CPM) DevicesCigna2026-08-15
    Push-Rim Activated Power-Assist Device (E0986) — Manual Wheelchair Accessorymoda_health_plan_inc2026-08-13
    Beds and Mattresses (for Ohio Only)Colorado Rocky Mountain Health Plans2026-08-01
    Beds and Mattresses (for Kentucky Only)UnitedHealthcare2026-08-01
    Pneumatic Compression Devices (for Nebraska Only)UnitedHealthcare2026-08-01
    Indications for Coverage — Hospital beds, support surfaces, and safety enclosure beds (DME)Colorado Rocky Mountain Health Plans2026-08-01

    Related Codes

    HCPCS-A9150-NON-PRESCRIPTION-DRUGS

    HCPCS Level II A9150: Non-prescription Drugs

    HCPCS-A9152-SINGLE-ORAL-VITAMIN-MINERAL-DOSE

    HCPCS A9152: Single Oral Vitamin/Mineral/Trace Element

    HCPCS-A9153-MULTIVITAMIN-ORAL-PER-DOSE

    HCPCS A9153: Multiple Vitamins, Oral, Per Dose

    HCPCS-A9154-ARTIFICIAL-SALIVA-1ML

    HCPCS Level II A9154: Artificial saliva, 1 ml

    HCPCS-A9155-ARTIFICIAL-SALIVA-30ML

    HCPCS Level II A9155: Artificial Saliva, 30 mL

    HCPCS-A9156-ORAL-MUCOADHESIVE-PER-1ML

    HCPCS Level II A9156: Oral Mucoadhesive, Per 1 ml

    HCPCS-A9180-PEDICULOSIS-TOPICAL-TREATMENT-PATIENT-ADMINISTRATION

    HCPCS Level II A9180: Pediculosis Topical Treatment for Patient/Caretaker

    HCPCS-A9268-PROGRAMMER-TRANSIENT-INGESTED-CAPSULE

    HCPCS Level II A9268: Programmer for Transient Orally Ingested Capsule

    HCPCS-A9269-PROGRAMMABLE-TRANSIENT-ORAL-CAPSULE

    HCPCS Level II A9269: Programmable Orally Ingested Capsule, Per Month

    HCPCS-A9270-NON-COVERED-ITEM-OR-SERVICE

    HCPCS A9270: Non-covered Item or Service

    Showing 1–10 of 138

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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